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The map label for this gene is rhtC [C]

Identifier: 15602592

GI number: 15602592

Start: 857343

End: 857987

Strand: Reverse

Name: rhtC [C]

Synonym: PM0727

Alternate gene names: 15602592

Gene position: 857987-857343 (Counterclockwise)

Preceding gene: 15602593

Following gene: 15602591

Centisome position: 38.01

GC content: 36.74

Gene sequence:

>645_bases
GTGATGTTAAATCTTATTATTGTACATTTTTTCGGTTTAATCACGCCAGGACCCGACTTTTTTTATGTCAGTCGATTAGC
TGCCAGTAATTCACGTCGTAATGCACTTTGTGCCGTGATTGGTATTACCTTAGGGGTGTTGTTTTGGGCATTAGCCTCTA
TTTTAGGTTTAGCCATATTATTTAATACGGTTCCTGTTTTACAGGGATTAGTCATGACTTTAGGCGGTGGGTATTTAGCC
TACTTGGGTTACCTTATGTTAAAAAGTCAACAAAATGTGGTTTTCGAGCCAGTTTCTGAACAAGAACAAAATAAACAGAC
CAGCATCAAAAAAGAAATCACCAAAGGGCTTTTAGTGAATTTATCTAATGCTAAAGCGGTGATTTACTTTGCTAGTGTGA
TGTCTTTGGTTTTAGTTAATTTAACCCAAACATGGCAGATCTGGAGCGCACTTTTGATCATTGTATTGGAAACTTTCCTG
TATTTTTATGCCATTTCAATTGTTTTTTCACGTCAACAGGCAAAGCAGTTTTATAGTCAATATAGCCGATATATTGATCA
TCTTTCAGGCGTGATTTTTCTGCTGTTTGGTGTGTATTTAATGTATAGTGGTATCGGGGAAATGACCCCACTTATCTCGA
AATGA

Upstream 100 bases:

>100_bases
ATAAATTAGAAAGCGGGTTTGGCATTATGTTAGATGATATACTTGCGGCAATTTATGCAGTATTGGTGATTTTTATTTTA
CGTCTCTGGTTTTAGGATAA

Downstream 100 bases:

>100_bases
TGCCATTGTGGTGGTCATTTCATATAGCGCGATATAGCAAAAGGGGATAATAATATGACATTACGTGTGGCAATCGTCGG
TGCTGGCGGCAGAATGGGGC

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MMLNLIIVHFFGLITPGPDFFYVSRLAASNSRRNALCAVIGITLGVLFWALASILGLAILFNTVPVLQGLVMTLGGGYLA
YLGYLMLKSQQNVVFEPVSEQEQNKQTSIKKEITKGLLVNLSNAKAVIYFASVMSLVLVNLTQTWQIWSALLIIVLETFL
YFYAISIVFSRQQAKQFYSQYSRYIDHLSGVIFLLFGVYLMYSGIGEMTPLISK

Sequences:

>Translated_214_residues
MMLNLIIVHFFGLITPGPDFFYVSRLAASNSRRNALCAVIGITLGVLFWALASILGLAILFNTVPVLQGLVMTLGGGYLA
YLGYLMLKSQQNVVFEPVSEQEQNKQTSIKKEITKGLLVNLSNAKAVIYFASVMSLVLVNLTQTWQIWSALLIIVLETFL
YFYAISIVFSRQQAKQFYSQYSRYIDHLSGVIFLLFGVYLMYSGIGEMTPLISK
>Mature_214_residues
MMLNLIIVHFFGLITPGPDFFYVSRLAASNSRRNALCAVIGITLGVLFWALASILGLAILFNTVPVLQGLVMTLGGGYLA
YLGYLMLKSQQNVVFEPVSEQEQNKQTSIKKEITKGLLVNLSNAKAVIYFASVMSLVLVNLTQTWQIWSALLIIVLETFL
YFYAISIVFSRQQAKQFYSQYSRYIDHLSGVIFLLFGVYLMYSGIGEMTPLISK

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=205, Percent_Identity=37.0731707317073, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786522, Length=207, Percent_Identity=25.6038647342995, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23950; Mature: 23950

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLNLIIVHFFGLITPGPDFFYVSRLAASNSRRNALCAVIGITLGVLFWALASILGLAIL
CHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNTVPVLQGLVMTLGGGYLAYLGYLMLKSQQNVVFEPVSEQEQNKQTSIKKEITKGLLVN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHC
LSNAKAVIYFASVMSLVLVNLTQTWQIWSALLIIVLETFLYFYAISIVFSRQQAKQFYSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSRYIDHLSGVIFLLFGVYLMYSGIGEMTPLISK
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHCCC
>Mature Secondary Structure
MMLNLIIVHFFGLITPGPDFFYVSRLAASNSRRNALCAVIGITLGVLFWALASILGLAIL
CHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNTVPVLQGLVMTLGGGYLAYLGYLMLKSQQNVVFEPVSEQEQNKQTSIKKEITKGLLVN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHC
LSNAKAVIYFASVMSLVLVNLTQTWQIWSALLIIVLETFLYFYAISIVFSRQQAKQFYSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSRYIDHLSGVIFLLFGVYLMYSGIGEMTPLISK
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]