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The map label for this gene is aroG [H]

Identifier: 15602428

GI number: 15602428

Start: 646913

End: 647998

Strand: Direct

Name: aroG [H]

Synonym: PM0563

Alternate gene names: 15602428

Gene position: 646913-647998 (Clockwise)

Preceding gene: 15602427

Following gene: 15602429

Centisome position: 28.66

GC content: 41.71

Gene sequence:

>1086_bases
ATGACAGAATATAAAAATGAAATTTATATCGAAAATGATGACACCAGAATTGATAAAATTGAGCAAGTTTTACCGCCTGT
GGCGTTATTAGAAAAATTTCCTGCCAGTGATGTGGCAGTAGAAACCGTCAGACAAACACGAAAAAAAGCACATAATATTA
TTCATCGAAAAGATGACCGTTTATTAGTTGTCATGGGACCTTGTTCCATTCATGATCCTGTTTCTGCGCTGGAGTATGCG
AAACGGATTAAAATGATGCGCGAAAAATACCAAGATAGCTTGGAGATTATTATGCGTGTCTATTTTGAAAAACCGCGAAC
CACGGTAGGGTGGAAAGGCTTGATTAATGATCCTCACCTAAATGGTACCTTTGAGCTGAATGAAGGGTTGCGTCTTGCGC
GTAAATTATTATCGGACGTTAATGATTTAGGGGTACCGGCTGCGGGTGAATTTTTGGACATGATTACACCACAATATCTG
GCTGATTTCATGAGTTGGGGTGCGATTGGTGCCAGAACCACAGAATCACAGGTGCACCGTGAACTTGCCTCTGGTCTATC
TTGTGCAGTTGGCTTTAAAAATGGCACGAATGGTGGGGTCAGAATCGCGTTAGATGCGATTGGGGCAGCAGAAGCACCAC
ATTATTTTCTTTCTGTCACGAAATTTGGTCATTCTGCGATTGTATCTACAAAAGGGAATGAAGACTGCCACATTATTTTA
CGAGGCGGTGATAAAGGTCCTAATTATGATGCAGAGCATATTGCTATGGTTTGTGCAGAGATCGAAAAAACAGGGCGTAT
TCCACATGTGATGGTCGATTTCAGCCATGCTAACAGTTGTAAACAATTTAAAAAACAATTAGAGGTTTGTGACAGTGTTT
GCCAGCAAATCGCTATGGGTTCTACTCAAATCTTTGGTGTGATGGTAGAAAGCCATCTTGTTGAAGGGCGACAAGATTTA
GTAGATGGAAAAGCGGTCACTTATGGGCAGAGTATCACGGACGCCTGTATTGGGTGGGAAGATAGCGAGAAAGTTTTGGA
ATCGCTTTCAAAAGCTGTCATCCAACGCCGAAATTTGCAGCAATAA

Upstream 100 bases:

>100_bases
ATTGGTGCTAGATTGGCAGTATCAATGATTTTGATAAAATAACCTATTGAAAAATAAGATTAAAAAATGAACCGTTTTAT
AAGAAGTAAGTGAGCGCAGT

Downstream 100 bases:

>100_bases
ATACAAGTTAAAGCGTCAGTGAATCTGGCGCTTTTTCTTTTCCTCCAGTCAGATAGCATAATTCTCTTTTATCCTCCCTT
TATTTTCCTCTTTAACCTTG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTEYKNEIYIENDDTRIDKIEQVLPPVALLEKFPASDVAVETVRQTRKKAHNIIHRKDDRLLVVMGPCSIHDPVSALEYA
KRIKMMREKYQDSLEIIMRVYFEKPRTTVGWKGLINDPHLNGTFELNEGLRLARKLLSDVNDLGVPAAGEFLDMITPQYL
ADFMSWGAIGARTTESQVHRELASGLSCAVGFKNGTNGGVRIALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIIL
RGGDKGPNYDAEHIAMVCAEIEKTGRIPHVMVDFSHANSCKQFKKQLEVCDSVCQQIAMGSTQIFGVMVESHLVEGRQDL
VDGKAVTYGQSITDACIGWEDSEKVLESLSKAVIQRRNLQQ

Sequences:

>Translated_361_residues
MTEYKNEIYIENDDTRIDKIEQVLPPVALLEKFPASDVAVETVRQTRKKAHNIIHRKDDRLLVVMGPCSIHDPVSALEYA
KRIKMMREKYQDSLEIIMRVYFEKPRTTVGWKGLINDPHLNGTFELNEGLRLARKLLSDVNDLGVPAAGEFLDMITPQYL
ADFMSWGAIGARTTESQVHRELASGLSCAVGFKNGTNGGVRIALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIIL
RGGDKGPNYDAEHIAMVCAEIEKTGRIPHVMVDFSHANSCKQFKKQLEVCDSVCQQIAMGSTQIFGVMVESHLVEGRQDL
VDGKAVTYGQSITDACIGWEDSEKVLESLSKAVIQRRNLQQ
>Mature_360_residues
TEYKNEIYIENDDTRIDKIEQVLPPVALLEKFPASDVAVETVRQTRKKAHNIIHRKDDRLLVVMGPCSIHDPVSALEYAK
RIKMMREKYQDSLEIIMRVYFEKPRTTVGWKGLINDPHLNGTFELNEGLRLARKLLSDVNDLGVPAAGEFLDMITPQYLA
DFMSWGAIGARTTESQVHRELASGLSCAVGFKNGTNGGVRIALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIILR
GGDKGPNYDAEHIAMVCAEIEKTGRIPHVMVDFSHANSCKQFKKQLEVCDSVCQQIAMGSTQIFGVMVESHLVEGRQDLV
DGKAVTYGQSITDACIGWEDSEKVLESLSKAVIQRRNLQQ

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=347, Percent_Identity=68.8760806916427, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI1787996, Length=345, Percent_Identity=55.3623188405797, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1788953, Length=331, Percent_Identity=51.0574018126888, Blast_Score=340, Evalue=6e-95,
Organism=Saccharomyces cerevisiae, GI6319726, Length=351, Percent_Identity=52.991452991453, Blast_Score=374, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6320240, Length=366, Percent_Identity=48.6338797814208, Blast_Score=350, Evalue=1e-97,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 40132; Mature: 40001

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYKNEIYIENDDTRIDKIEQVLPPVALLEKFPASDVAVETVRQTRKKAHNIIHRKDDR
CCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LLVVMGPCSIHDPVSALEYAKRIKMMREKYQDSLEIIMRVYFEKPRTTVGWKGLINDPHL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NGTFELNEGLRLARKLLSDVNDLGVPAAGEFLDMITPQYLADFMSWGAIGARTTESQVHR
CCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHH
ELASGLSCAVGFKNGTNGGVRIALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIIL
HHHCCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEE
RGGDKGPNYDAEHIAMVCAEIEKTGRIPHVMVDFSHANSCKQFKKQLEVCDSVCQQIAMG
ECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
STQIFGVMVESHLVEGRQDLVDGKAVTYGQSITDACIGWEDSEKVLESLSKAVIQRRNLQ
CHHHHHHHHHHHHHHCHHHHHCCCCEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
Q
C
>Mature Secondary Structure 
TEYKNEIYIENDDTRIDKIEQVLPPVALLEKFPASDVAVETVRQTRKKAHNIIHRKDDR
CCCCCEEEEECCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LLVVMGPCSIHDPVSALEYAKRIKMMREKYQDSLEIIMRVYFEKPRTTVGWKGLINDPHL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NGTFELNEGLRLARKLLSDVNDLGVPAAGEFLDMITPQYLADFMSWGAIGARTTESQVHR
CCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHH
ELASGLSCAVGFKNGTNGGVRIALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIIL
HHHCCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEE
RGGDKGPNYDAEHIAMVCAEIEKTGRIPHVMVDFSHANSCKQFKKQLEVCDSVCQQIAMG
ECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
STQIFGVMVESHLVEGRQDLVDGKAVTYGQSITDACIGWEDSEKVLESLSKAVIQRRNLQ
CHHHHHHHHHHHHHHCHHHHHCCCCEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]