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The map label for this gene is lolE [H]

Identifier: 15602427

GI number: 15602427

Start: 645513

End: 646766

Strand: Direct

Name: lolE [H]

Synonym: PM0562

Alternate gene names: 15602427

Gene position: 645513-646766 (Clockwise)

Preceding gene: 15602426

Following gene: 15602428

Centisome position: 28.59

GC content: 40.19

Gene sequence:

>1254_bases
ATGAATACACCGTTTTTTATTAGCTGGCGTTATCAGCGGAGTAAGCAAAAAAATCGCTTAGTTTCTTTGATTTCTGCGTT
TTCTAGCATTGGTATTGCACTGGGCGTTGCTGTGCTAATTGTGGGACTGAGCGCCATGAATGGATTTGAACGAGAGTTGA
ATCAACGCATTTTAGCGGTGGTTCCGCATGTTGAAATAATGGCTTATCCCAATGAAAAAGGTACCAGTAGTATTAAACCT
TGGCAACCCTTGGTTAAAACATTAGCGCAGCATGAGCAAATCGACGGCATTTCGCCCTATGTGACTTTTACTGCTTTAGT
TGAAAATGGCACTAAACTCAAAGTGGTGCAAGTCAAAGGGGTAGAAAAGTCCGCACAAGATCAAGTCAGCGCGTTAGGGC
AATTTGTATTAGATGAAGGGTGGAAGGTTTTTGAACAGCAGTCTGGTTTGATTTTAGGTTATGGCATTGCTCGTGATCTG
GACGTAGTAGCTGGGGATTGGGTGAGTTTACTGATTTCGCCACCCAATGAGCAAAATCAATTGGCTCAGCCCATTCGTCA
TCGCATCCAAGTCAGTGGCATTTTACGTTTAGAAGGTCAATTAGATCACAGCTATGCTTTATTACCGCTTACACAAGCTC
AGACACTATTAGGTATAAGCACAGACGAAGTACATGGTGTGGAACTGAAAGTGAAACAGCCATTTCAAGTACAAACATTA
ACGTTTCCGATGTTACAGGACTACCCGCAAGCCCTTTATGCACAACATTGGATTCATAAATTTGGTTATATGTATCGTGA
TATCCAATTAATTCGTAGCGTAATGTATATCGCTATGGTATTGGTCATCGGTGTAGCTTGCTTTAATATTATTTCGACCT
TGATTATGGCGGTGAAAGATAAACAAGGTGATATTGCGATTATGCGTACTTTAGGGGCAAATAATCGCTTTATTAAGCAA
ATTTTTATTTGGTATGGCTTGCAAGCGGGCATGAAAGGGTGTTTAATTGGCATCTTTTTAGGCATTATTTTGGCGTTAAA
CTTAACCTCAATCATACAGGGGGTTGAATATTTACTAGGGCGGAAACTGCTATCTGATGGGATTTATTTTGTGGATTTCT
TACCAAGTGAATTACATTGGCAAGATATTTTGCTCGTATTCTGTTCAGCATTAATTTTGAGTTTACTTGCTAGCCTATAT
CCCGCAAATCGTGCCGCCAAATTACAACCTGCACAAGTTTTGAGTCATTATTAG

Upstream 100 bases:

>100_bases
AAATATTGCGTTTTTATTAGTCACACATGATTTAACGCTAGCCGAAAAACTATCGCGTCGTTTAGTGATGCAAGATGGTG
TATTACGTGAGGAGCATTAA

Downstream 100 bases:

>100_bases
ATGAATTATTATAAATGAAACCGAAAACTAGTTTACTAGTGTATTTATTGGTGCTAGATTGGCAGTATCAATGATTTTGA
TAAAATAACCTATTGAAAAA

Product: outer membrane-specific lipoprotein transporter subunit LolE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNTPFFISWRYQRSKQKNRLVSLISAFSSIGIALGVAVLIVGLSAMNGFERELNQRILAVVPHVEIMAYPNEKGTSSIKP
WQPLVKTLAQHEQIDGISPYVTFTALVENGTKLKVVQVKGVEKSAQDQVSALGQFVLDEGWKVFEQQSGLILGYGIARDL
DVVAGDWVSLLISPPNEQNQLAQPIRHRIQVSGILRLEGQLDHSYALLPLTQAQTLLGISTDEVHGVELKVKQPFQVQTL
TFPMLQDYPQALYAQHWIHKFGYMYRDIQLIRSVMYIAMVLVIGVACFNIISTLIMAVKDKQGDIAIMRTLGANNRFIKQ
IFIWYGLQAGMKGCLIGIFLGIILALNLTSIIQGVEYLLGRKLLSDGIYFVDFLPSELHWQDILLVFCSALILSLLASLY
PANRAAKLQPAQVLSHY

Sequences:

>Translated_417_residues
MNTPFFISWRYQRSKQKNRLVSLISAFSSIGIALGVAVLIVGLSAMNGFERELNQRILAVVPHVEIMAYPNEKGTSSIKP
WQPLVKTLAQHEQIDGISPYVTFTALVENGTKLKVVQVKGVEKSAQDQVSALGQFVLDEGWKVFEQQSGLILGYGIARDL
DVVAGDWVSLLISPPNEQNQLAQPIRHRIQVSGILRLEGQLDHSYALLPLTQAQTLLGISTDEVHGVELKVKQPFQVQTL
TFPMLQDYPQALYAQHWIHKFGYMYRDIQLIRSVMYIAMVLVIGVACFNIISTLIMAVKDKQGDIAIMRTLGANNRFIKQ
IFIWYGLQAGMKGCLIGIFLGIILALNLTSIIQGVEYLLGRKLLSDGIYFVDFLPSELHWQDILLVFCSALILSLLASLY
PANRAAKLQPAQVLSHY
>Mature_417_residues
MNTPFFISWRYQRSKQKNRLVSLISAFSSIGIALGVAVLIVGLSAMNGFERELNQRILAVVPHVEIMAYPNEKGTSSIKP
WQPLVKTLAQHEQIDGISPYVTFTALVENGTKLKVVQVKGVEKSAQDQVSALGQFVLDEGWKVFEQQSGLILGYGIARDL
DVVAGDWVSLLISPPNEQNQLAQPIRHRIQVSGILRLEGQLDHSYALLPLTQAQTLLGISTDEVHGVELKVKQPFQVQTL
TFPMLQDYPQALYAQHWIHKFGYMYRDIQLIRSVMYIAMVLVIGVACFNIISTLIMAVKDKQGDIAIMRTLGANNRFIKQ
IFIWYGLQAGMKGCLIGIFLGIILALNLTSIIQGVEYLLGRKLLSDGIYFVDFLPSELHWQDILLVFCSALILSLLASLY
PANRAAKLQPAQVLSHY

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=421, Percent_Identity=51.5439429928741, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1787360, Length=417, Percent_Identity=28.0575539568345, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46565; Mature: 46565

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPFFISWRYQRSKQKNRLVSLISAFSSIGIALGVAVLIVGLSAMNGFERELNQRILAV
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VPHVEIMAYPNEKGTSSIKPWQPLVKTLAQHEQIDGISPYVTFTALVENGTKLKVVQVKG
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEEC
VEKSAQDQVSALGQFVLDEGWKVFEQQSGLILGYGIARDLDVVAGDWVSLLISPPNEQNQ
CCHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCHHHHHCCHHEEEECCCCCHHH
LAQPIRHRIQVSGILRLEGQLDHSYALLPLTQAQTLLGISTDEVHGVELKVKQPFQVQTL
HHHHHHHHHHHHHEEEEECCCCCCEEEEEEHHHHHHHCCCCCCCCCEEEEECCCCEEEEE
TFPMLQDYPQALYAQHWIHKFGYMYRDIQLIRSVMYIAMVLVIGVACFNIISTLIMAVKD
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KQGDIAIMRTLGANNRFIKQIFIWYGLQAGMKGCLIGIFLGIILALNLTSIIQGVEYLLG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLLSDGIYFVDFLPSELHWQDILLVFCSALILSLLASLYPANRAAKLQPAQVLSHY
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MNTPFFISWRYQRSKQKNRLVSLISAFSSIGIALGVAVLIVGLSAMNGFERELNQRILAV
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VPHVEIMAYPNEKGTSSIKPWQPLVKTLAQHEQIDGISPYVTFTALVENGTKLKVVQVKG
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEEC
VEKSAQDQVSALGQFVLDEGWKVFEQQSGLILGYGIARDLDVVAGDWVSLLISPPNEQNQ
CCHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCHHHHHCCHHEEEECCCCCHHH
LAQPIRHRIQVSGILRLEGQLDHSYALLPLTQAQTLLGISTDEVHGVELKVKQPFQVQTL
HHHHHHHHHHHHHEEEEECCCCCCEEEEEEHHHHHHHCCCCCCCCCEEEEECCCCEEEEE
TFPMLQDYPQALYAQHWIHKFGYMYRDIQLIRSVMYIAMVLVIGVACFNIISTLIMAVKD
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KQGDIAIMRTLGANNRFIKQIFIWYGLQAGMKGCLIGIFLGIILALNLTSIIQGVEYLLG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLLSDGIYFVDFLPSELHWQDILLVFCSALILSLLASLYPANRAAKLQPAQVLSHY
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]