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The map label for this gene is aroC [H]

Identifier: 15602224

GI number: 15602224

Start: 421047

End: 422120

Strand: Direct

Name: aroC [H]

Synonym: PM0359

Alternate gene names: 15602224

Gene position: 421047-422120 (Clockwise)

Preceding gene: 15602223

Following gene: 15602225

Centisome position: 18.65

GC content: 47.3

Gene sequence:

>1074_bases
ATGGCAGGAAATACAATTGGGCAACTTTTTCAGGTAACAACATTTGGTGAATCACATGGGATTGCGCTCGGCTGTATTGT
GGATGGTGTGCCACCCGGGCTGAGTTTATCTGAGGCAGACATTCAACCTGATTTAGATCGCCGTAAACCTGGTACATCGC
GTTATACCACACCGCGTCGTGAAGATGACGAAGTGCAGATTTTATCGGGTGTGTTTGAAGGTAAAACCACGGGGACGAGT
ATCGGGATGATCATCAAAAATGCGGATCAACGTTCGCAAGATTATGGTGACATTAAAGATCGTTTTCGTCCCGGACACGC
TGATTTTACCTACCAACAAAAATACGGGATACGCGATTATCGTGGCGGTGGGCGTTCTTCCGCACGAGAAACAGCCATGC
GAGTTGCCGCAGGTGCCATCGCGAAAAAATATTTGCGTGAGCATTTTGGCGTAGAGGTGAGAGGCTTTTTGGCTCAAATT
GGTGATGTGGCGATTGCCCCGCAAGTGATTGAGCAAATTGATTGGCAACAAGTCAACAGTAATCCGTTCTTTTGTCCGGA
TCCGAGTGCGGTGGAAAAATTTGATGAATTAATTCGTCAGCTGAAAAAAGAGGGTGATTCGATTGGGGCAAAATTAACGG
TAGTGGCAGAAAATGTGCCAGTTGGCTTGGGTGAACCCGTGTTTGATCGTTTAGATGCGGATCTGGCTCACGCCTTGATG
GGCATTAATGCGGTGAAAGCAGTGGAGATTGGTGATGGCTTTGCGGTGGTTAATCAGCGTGGTTCAGCACATCGCGATGA
AATGACACCGGAAGGCTTTTTGTCTAATCATGCGGGTGGTATTCTGGGCGGTATTAGCTCAGGTCAACCGATTGTCGCGA
CAATTGCTTTAAAACCAACTTCAAGCATCACAATTCCGGGGCGTTCAGTCAATCTTGCCAATGAGCCTGTCGAGGTGATT
ACGAAAGGACGTCATGATCCTTGTGTGGGGATTCGTGCCGTACCGATTGCTGAAGCGATGGTTGCGATTGTCTTACTCGA
TCACTTATTAAGACATAAAGCGCAAAATAGATAA

Upstream 100 bases:

>100_bases
ATTTAACCAGTTGGATGTCTTCATTAAAAATCAGGTAACCAACGAAGAAATTAAACTGAATCAACAATGTTTTCCAACGC
AAAAACAGGAAGGATAAAAG

Downstream 100 bases:

>100_bases
TGATGAAGTCATGTGCAAAGGATGGCACCAACACGAGGTTTAATTGAGGATGACATCCACGAATATGATGAAAAAAAGCG
TTAATATCGCGGTTATGTTG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MAGNTIGQLFQVTTFGESHGIALGCIVDGVPPGLSLSEADIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTS
IGMIIKNADQRSQDYGDIKDRFRPGHADFTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREHFGVEVRGFLAQI
GDVAIAPQVIEQIDWQQVNSNPFFCPDPSAVEKFDELIRQLKKEGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAHALM
GINAVKAVEIGDGFAVVNQRGSAHRDEMTPEGFLSNHAGGILGGISSGQPIVATIALKPTSSITIPGRSVNLANEPVEVI
TKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRHKAQNR

Sequences:

>Translated_357_residues
MAGNTIGQLFQVTTFGESHGIALGCIVDGVPPGLSLSEADIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTS
IGMIIKNADQRSQDYGDIKDRFRPGHADFTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREHFGVEVRGFLAQI
GDVAIAPQVIEQIDWQQVNSNPFFCPDPSAVEKFDELIRQLKKEGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAHALM
GINAVKAVEIGDGFAVVNQRGSAHRDEMTPEGFLSNHAGGILGGISSGQPIVATIALKPTSSITIPGRSVNLANEPVEVI
TKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRHKAQNR
>Mature_356_residues
AGNTIGQLFQVTTFGESHGIALGCIVDGVPPGLSLSEADIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTSI
GMIIKNADQRSQDYGDIKDRFRPGHADFTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREHFGVEVRGFLAQIG
DVAIAPQVIEQIDWQQVNSNPFFCPDPSAVEKFDELIRQLKKEGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAHALMG
INAVKAVEIGDGFAVVNQRGSAHRDEMTPEGFLSNHAGGILGGISSGQPIVATIALKPTSSITIPGRSVNLANEPVEVIT
KGRHDPCVGIRAVPIAEAMVAIVLLDHLLRHKAQNR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=356, Percent_Identity=76.4044943820225, Blast_Score=541, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=47.2826086956522, Blast_Score=323, Evalue=3e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 38425; Mature: 38294

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNTIGQLFQVTTFGESHGIALGCIVDGVPPGLSLSEADIQPDLDRRKPGTSRYTTPRR
CCCCHHHHHEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
EDDEVQILSGVFEGKTTGTSIGMIIKNADQRSQDYGDIKDRFRPGHADFTYQQKYGIRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHCCCCCCCCEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLREHFGVEVRGFLAQIGDVAIAPQVIEQIDWQQVNS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCHHHCCC
NPFFCPDPSAVEKFDELIRQLKKEGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAHALM
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
GINAVKAVEIGDGFAVVNQRGSAHRDEMTPEGFLSNHAGGILGGISSGQPIVATIALKPT
CCCCEEEEEECCCEEEECCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEEEECCC
SSITIPGRSVNLANEPVEVITKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRHKAQNR
CEEEECCCCCCCCCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGNTIGQLFQVTTFGESHGIALGCIVDGVPPGLSLSEADIQPDLDRRKPGTSRYTTPRR
CCCHHHHHEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
EDDEVQILSGVFEGKTTGTSIGMIIKNADQRSQDYGDIKDRFRPGHADFTYQQKYGIRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHCCCCCCCCEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLREHFGVEVRGFLAQIGDVAIAPQVIEQIDWQQVNS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCHHHCCC
NPFFCPDPSAVEKFDELIRQLKKEGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAHALM
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
GINAVKAVEIGDGFAVVNQRGSAHRDEMTPEGFLSNHAGGILGGISSGQPIVATIALKPT
CCCCEEEEEECCCEEEECCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEEEECCC
SSITIPGRSVNLANEPVEVITKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRHKAQNR
CEEEECCCCCCCCCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA