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The map label for this gene is ftsW [H]

Identifier: 15602006

GI number: 15602006

Start: 166885

End: 168075

Strand: Direct

Name: ftsW [H]

Synonym: PM0141

Alternate gene names: 15602006

Gene position: 166885-168075 (Clockwise)

Preceding gene: 15602005

Following gene: 15602007

Centisome position: 7.39

GC content: 40.72

Gene sequence:

>1191_bases
ATGCCATTTTTAGATAAAGTAAAGCAGCAATATGAGGATTGGACGCGTATTACACCGAGTAATTTGTTATACGATCGTGC
CTTGCTGTTGCTCTTTTTTGTTTTACTTTTAATTGGCTTATTGGCCGTTTCTTCTGCGTCTATTCCAGTGGGAACCCGCT
TATTTAAAGATCCGTTTTACTTCGCCAAGCGTGATGCGATTTATGTATTTCTTTCCTGTGTGACCTGTTATCTGTGTGTG
CAAGTGCCAATGGAGAAATGGGAACAATGGCATGTCCGCTTATTTGCTTTTGCTATTTTTCTGTTGATTCTAGTACTCAT
TCCTGGCATTGGCTTATCCGTAAATGGGGCGCGTCGTTGGATTCCGATGGTGTTATTTAACTTCCAGCCAGCAGAATTTG
CGAAATTGGCGCTGACGTGTTTTTTAGCCAGCTATTTTACGCGTAAATATGATGAGGTGAGAAGTCGTAAACTCAGTGCA
TTTAAACCCTTTGCGTTGATGGGATTGATGGGACTCTTTTTATTATCACAGCCTGATCTCGGCAGTACCGTCGTTCTTTT
TGTGATTACTTTCGGACTATTATTTATTGTTGGGGCTAACTTTTGGCAGTTTGTTGGGTTAATGGCGTTTGGTGGACTTT
TGTTTGTGTGGTTAGTTTTATCTTCCGCTTATCGTTTAAAACGTTTCACGGGTTTTCTTGATCCTTTCAAAGATCCCTAC
GGTACCGGTTTCCAACTCTCTAACTCTTTAATGGCATTTGGGCGTGGTGAATGGGTAGGAGAAGGACTCGGGAATTCCAT
TCAAAAATTAGAATATTTACCTGAAGCGCATACTGACTTCGTGATGGCAGTAGTGGGCGAGGAGTTCGGTTTTTTAGGCA
TTTTAGTGATTGTGATATTACTCGGGTTGTTAATTTTCCGTGCCATGAAAATTGGGCGGGAATCCTTATTATTAGAACAA
CGCTTTAAAGGTTTCTTTGCCTTTGGTATCAGCTTTTGGATTTTCTTCCAAGGTTTTGTCAATTTAGGGATGTCTCTCGG
CTTGTTACCTACTAAAGGTTTAACCTTTCCGCTCATCAGTTATGGTGGCTCCAGTTTAATTATTATGTCTATGACCATTG
GCTTGTTACTGCGAATTGATCATGAAAATCGATTAATGCGAATTGGGCAAGCACGTTTACGGGATGATTAA

Upstream 100 bases:

>100_bases
TACTTTCTCCTGCTTGTGCCAGTTTAGATCAGTTTAGCAGTTTCGAACAACGTGGTGATGAATTTACACGTTTAGCAAAA
TTAAGTTAGGTGAAAGCAGT

Downstream 100 bases:

>100_bases
AATTTACAAAAAATGACCGCACTTTGAAGGCAAAAATCACGTGGTTTTTGTGGGTGCATAAAGCAAAGGGACGGGATGTG
AGCGAACAAAAGAAAAGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPFLDKVKQQYEDWTRITPSNLLYDRALLLLFFVLLLIGLLAVSSASIPVGTRLFKDPFYFAKRDAIYVFLSCVTCYLCV
QVPMEKWEQWHVRLFAFAIFLLILVLIPGIGLSVNGARRWIPMVLFNFQPAEFAKLALTCFLASYFTRKYDEVRSRKLSA
FKPFALMGLMGLFLLSQPDLGSTVVLFVITFGLLFIVGANFWQFVGLMAFGGLLFVWLVLSSAYRLKRFTGFLDPFKDPY
GTGFQLSNSLMAFGRGEWVGEGLGNSIQKLEYLPEAHTDFVMAVVGEEFGFLGILVIVILLGLLIFRAMKIGRESLLLEQ
RFKGFFAFGISFWIFFQGFVNLGMSLGLLPTKGLTFPLISYGGSSLIIMSMTIGLLLRIDHENRLMRIGQARLRDD

Sequences:

>Translated_396_residues
MPFLDKVKQQYEDWTRITPSNLLYDRALLLLFFVLLLIGLLAVSSASIPVGTRLFKDPFYFAKRDAIYVFLSCVTCYLCV
QVPMEKWEQWHVRLFAFAIFLLILVLIPGIGLSVNGARRWIPMVLFNFQPAEFAKLALTCFLASYFTRKYDEVRSRKLSA
FKPFALMGLMGLFLLSQPDLGSTVVLFVITFGLLFIVGANFWQFVGLMAFGGLLFVWLVLSSAYRLKRFTGFLDPFKDPY
GTGFQLSNSLMAFGRGEWVGEGLGNSIQKLEYLPEAHTDFVMAVVGEEFGFLGILVIVILLGLLIFRAMKIGRESLLLEQ
RFKGFFAFGISFWIFFQGFVNLGMSLGLLPTKGLTFPLISYGGSSLIIMSMTIGLLLRIDHENRLMRIGQARLRDD
>Mature_395_residues
PFLDKVKQQYEDWTRITPSNLLYDRALLLLFFVLLLIGLLAVSSASIPVGTRLFKDPFYFAKRDAIYVFLSCVTCYLCVQ
VPMEKWEQWHVRLFAFAIFLLILVLIPGIGLSVNGARRWIPMVLFNFQPAEFAKLALTCFLASYFTRKYDEVRSRKLSAF
KPFALMGLMGLFLLSQPDLGSTVVLFVITFGLLFIVGANFWQFVGLMAFGGLLFVWLVLSSAYRLKRFTGFLDPFKDPYG
TGFQLSNSLMAFGRGEWVGEGLGNSIQKLEYLPEAHTDFVMAVVGEEFGFLGILVIVILLGLLIFRAMKIGRESLLLEQR
FKGFFAFGISFWIFFQGFVNLGMSLGLLPTKGLTFPLISYGGSSLIIMSMTIGLLLRIDHENRLMRIGQARLRDD

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=377, Percent_Identity=50.132625994695, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI1786853, Length=328, Percent_Identity=32.6219512195122, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44882; Mature: 44751

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFLDKVKQQYEDWTRITPSNLLYDRALLLLFFVLLLIGLLAVSSASIPVGTRLFKDPFY
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHH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CCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]