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The map label for this gene is murG

Identifier: 15602007

GI number: 15602007

Start: 168153

End: 169217

Strand: Direct

Name: murG

Synonym: PM0142

Alternate gene names: 15602007

Gene position: 168153-169217 (Clockwise)

Preceding gene: 15602006

Following gene: 15602008

Centisome position: 7.45

GC content: 44.69

Gene sequence:

>1065_bases
GTGAGCGAACAAAAGAAAAGATTATTAGTCATGGCAGGTGGGACTGGAGGGCATGTTTTCCCTGCGATTGCGGTGGCACA
ATATTTACAACAACAAGGGTGGGATATTTGTTGGTTAGGGACGGCGGATCGTATGGAAGCGCAATTAGTGCCAAAACATC
ATATCCCTATTCAATTTATCCAAATTTCAGGCTTACGCGGTAAAGGGATAAAAGCTTTACTGAGTGCGCCTTTTAGTATT
TTTAGAGCAATATTACAGGCACGTAAAATTATTAAAGCCTATCAACCACATGCTGTATTAGGCATGGGGGGCTATGTGTC
TGGTCCGGGTGGCATTGCGGCAAAATTATGTGGCATCCCTGTGATTTTACATGAGCAAAATGCGGTAGCAGGCTTAACCA
ATAGTTGGTTAGCAAAAATTGCCAGACGAGTTTTACAAGCCTTTCCAACTGCGTTTCCCAATGCGGAAGTAGTTGGTAAT
CCCGTACGACAAACATTATTTTCTCAACCTACGCCAGAACAACGTTTTGCAGGGCGAGAAGGGAAATTACGTGTACTCGT
GGTAGGCGGTAGTCAGGGCGCAAGAGTCCTTAATCAAACGTTGCCCAATGTTGTTGCACAATTATCCGACAAACTTGAAG
TTCGTCATCAAGTTGGGCAAGGTGCCGTTGAGCAAGTCACGACATTGTATCCAGAACATGCTTCGGTCACCATCACGGAA
TTTATTGATAATATGGCAGACGCCTATGCTTGGGCGGATATCGTCATTTGTCGTTCAGGGGCTTTAACCGTAAGTGAACT
TGCTGCAGTAGGCGCAGCAGCGATTTTTGTGCCATTTCAGCATAAAGATCAACAACAGTATTTAAATGCGAAATATTTAG
CGGATGCCGGTGCGGCAACCATTATTCCACAAGCAGAATTGACTGCGGAGAAATTAGTGAGTGTATTAACGCAATTCGAT
CGTGAAACCTTGCAACAAATGGCAATTAAAGCAAAAGCCATGGCAACCCCACTCGCCGCACAACGTGTCGCGGAAGTGAT
TATCGAAGAAGCGAATCAAGATTAG

Upstream 100 bases:

>100_bases
AAGCACGTTTACGGGATGATTAAAATTTACAAAAAATGACCGCACTTTGAAGGCAAAAATCACGTGGTTTTTGTGGGTGC
ATAAAGCAAAGGGACGGGAT

Downstream 100 bases:

>100_bases
GAACGTGTAAATGATGAATTCAAAATGTGGTAAAGCTTTTCAGCAACGGGTAAGAGATATGATCCCGGAAATGCGCCGTG
TTCGTCAGATCCATTTTGTT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSEQKKRLLVMAGGTGGHVFPAIAVAQYLQQQGWDICWLGTADRMEAQLVPKHHIPIQFIQISGLRGKGIKALLSAPFSI
FRAILQARKIIKAYQPHAVLGMGGYVSGPGGIAAKLCGIPVILHEQNAVAGLTNSWLAKIARRVLQAFPTAFPNAEVVGN
PVRQTLFSQPTPEQRFAGREGKLRVLVVGGSQGARVLNQTLPNVVAQLSDKLEVRHQVGQGAVEQVTTLYPEHASVTITE
FIDNMADAYAWADIVICRSGALTVSELAAVGAAAIFVPFQHKDQQQYLNAKYLADAGAATIIPQAELTAEKLVSVLTQFD
RETLQQMAIKAKAMATPLAAQRVAEVIIEEANQD

Sequences:

>Translated_354_residues
MSEQKKRLLVMAGGTGGHVFPAIAVAQYLQQQGWDICWLGTADRMEAQLVPKHHIPIQFIQISGLRGKGIKALLSAPFSI
FRAILQARKIIKAYQPHAVLGMGGYVSGPGGIAAKLCGIPVILHEQNAVAGLTNSWLAKIARRVLQAFPTAFPNAEVVGN
PVRQTLFSQPTPEQRFAGREGKLRVLVVGGSQGARVLNQTLPNVVAQLSDKLEVRHQVGQGAVEQVTTLYPEHASVTITE
FIDNMADAYAWADIVICRSGALTVSELAAVGAAAIFVPFQHKDQQQYLNAKYLADAGAATIIPQAELTAEKLVSVLTQFD
RETLQQMAIKAKAMATPLAAQRVAEVIIEEANQD
>Mature_353_residues
SEQKKRLLVMAGGTGGHVFPAIAVAQYLQQQGWDICWLGTADRMEAQLVPKHHIPIQFIQISGLRGKGIKALLSAPFSIF
RAILQARKIIKAYQPHAVLGMGGYVSGPGGIAAKLCGIPVILHEQNAVAGLTNSWLAKIARRVLQAFPTAFPNAEVVGNP
VRQTLFSQPTPEQRFAGREGKLRVLVVGGSQGARVLNQTLPNVVAQLSDKLEVRHQVGQGAVEQVTTLYPEHASVTITEF
IDNMADAYAWADIVICRSGALTVSELAAVGAAAIFVPFQHKDQQQYLNAKYLADAGAATIIPQAELTAEKLVSVLTQFDR
ETLQQMAIKAKAMATPLAAQRVAEVIIEEANQD

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=352, Percent_Identity=63.6363636363636, Blast_Score=453, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_PASMU (P57817)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245079.1
- ProteinModelPortal:   P57817
- SMR:   P57817
- GeneID:   1243489
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0142
- NMPDR:   fig|272843.1.peg.142
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   PMUL272843:PM0142-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38139; Mature: 38007

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQKKRLLVMAGGTGGHVFPAIAVAQYLQQQGWDICWLGTADRMEAQLVPKHHIPIQFI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCCCEEEE
QISGLRGKGIKALLSAPFSIFRAILQARKIIKAYQPHAVLGMGGYVSGPGGIAAKLCGIP
EEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCE
VILHEQNAVAGLTNSWLAKIARRVLQAFPTAFPNAEVVGNPVRQTLFSQPTPEQRFAGRE
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHCCCCCCHHHHCCCC
GKLRVLVVGGSQGARVLNQTLPNVVAQLSDKLEVRHQVGQGAVEQVTTLYPEHASVTITE
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEHHH
FIDNMADAYAWADIVICRSGALTVSELAAVGAAAIFVPFQHKDQQQYLNAKYLADAGAAT
HHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHEEEECCCCCHHHHHCHHHHHCCCCEE
IIPQAELTAEKLVSVLTQFDRETLQQMAIKAKAMATPLAAQRVAEVIIEEANQD
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEQKKRLLVMAGGTGGHVFPAIAVAQYLQQQGWDICWLGTADRMEAQLVPKHHIPIQFI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCCCEEEE
QISGLRGKGIKALLSAPFSIFRAILQARKIIKAYQPHAVLGMGGYVSGPGGIAAKLCGIP
EEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCE
VILHEQNAVAGLTNSWLAKIARRVLQAFPTAFPNAEVVGNPVRQTLFSQPTPEQRFAGRE
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHCCCCCCHHHHCCCC
GKLRVLVVGGSQGARVLNQTLPNVVAQLSDKLEVRHQVGQGAVEQVTTLYPEHASVTITE
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEHHH
FIDNMADAYAWADIVICRSGALTVSELAAVGAAAIFVPFQHKDQQQYLNAKYLADAGAAT
HHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHEEEECCCCCHHHHHCHHHHHCCCCEE
IIPQAELTAEKLVSVLTQFDRETLQQMAIKAKAMATPLAAQRVAEVIIEEANQD
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100