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The map label for this gene is udk

Identifier: 15673642

GI number: 15673642

Start: 1709245

End: 1709865

Strand: Reverse

Name: udk

Synonym: L108994

Alternate gene names: 15673642

Gene position: 1709865-1709245 (Counterclockwise)

Preceding gene: 15673644

Following gene: 15673641

Centisome position: 72.28

GC content: 35.1

Gene sequence:

>621_bases
TTGAAGAAAACGTTGATTATTGGTGTCACTGGTGGGTCAGCAAGTGGAAAGACAAGTGTTTCACATGCTATTTTAGAAAC
TTTTTCAAATGAACGAATTGCAATGATTGAACATGATAGTTACTATAAAGATCAATCGCATTTGACTTTTGAAGAACGGA
CAAAAACGAACTACGACCATCCATTAGCCTTTGATACAGATTATTTAATTGCTCAATTAAAAGAGCTTCAGTATGGACGA
GCGGTTGATATTCCGATTTATGATTATGCAAAACATACGCGTTCACAAGAAACTTACCGTCAAGAACCTGTTGATGTTTT
AATCGTTGAGGGAATTTTGGTTTTAGAAGATGAACGTTTGCGTGATTTAATGGATATCAAAATATTTGTTGATACAGATG
ACGATGTGCGGATTATCCGTCGAATTCGCAGAGATATTGAAGAAAGAGGAAGAACTCTTGATTCAGTAATTACACAGTAT
TTAGATGCTGTTAAGCCAATGTATCATCAATTTATTGAACCAACAAAGAGATATGCAGATGTGATTATTCCTGAAGGGGT
CTCAAATACTGTTGGGGTTGATATTATTACGACGAAAATCGCTAGCATTTTAAACGACTAA

Upstream 100 bases:

>100_bases
TTTTGATGTGAACGCTTAAAAAGTAAAGAAATTGTCAGTTGATGACAAAAAGCTCAAAAATTGTGGTAGAATATATAGAA
GAAAATTTGGAGAATTAATT

Downstream 100 bases:

>100_bases
AAAAAGCTGTCTTTGACAGTTTTTTTGTTTTTGGCTAGTGAATCTCGTGAAAAATTGGAAAAATAAAAAAGCTAATTGTC
CTTAAATAGCAATAATGGTA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDHPLAFDTDYLIAQLKELQYGR
AVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERLRDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQY
LDAVKPMYHQFIEPTKRYADVIIPEGVSNTVGVDIITTKIASILND

Sequences:

>Translated_206_residues
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDHPLAFDTDYLIAQLKELQYGR
AVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERLRDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQY
LDAVKPMYHQFIEPTKRYADVIIPEGVSNTVGVDIITTKIASILND
>Mature_206_residues
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDHPLAFDTDYLIAQLKELQYGR
AVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERLRDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQY
LDAVKPMYHQFIEPTKRYADVIIPEGVSNTVGVDIITTKIASILND

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI301129207, Length=207, Percent_Identity=43.4782608695652, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI57863312, Length=207, Percent_Identity=43.4782608695652, Blast_Score=188, Evalue=2e-48,
Organism=Homo sapiens, GI18699734, Length=213, Percent_Identity=42.7230046948357, Blast_Score=188, Evalue=3e-48,
Organism=Homo sapiens, GI13899253, Length=216, Percent_Identity=42.5925925925926, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI209863022, Length=152, Percent_Identity=39.4736842105263, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI87082034, Length=206, Percent_Identity=49.5145631067961, Blast_Score=221, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=43.0622009569378, Blast_Score=179, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=43.0622009569378, Blast_Score=179, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI71981181, Length=210, Percent_Identity=36.6666666666667, Blast_Score=130, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6324339, Length=194, Percent_Identity=36.0824742268041, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320223, Length=206, Percent_Identity=27.6699029126214, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221458995, Length=219, Percent_Identity=41.5525114155251, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24649624, Length=217, Percent_Identity=41.9354838709677, Blast_Score=173, Evalue=8e-44,
Organism=Drosophila melanogaster, GI28573516, Length=202, Percent_Identity=40.5940594059406, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28573514, Length=202, Percent_Identity=40.5940594059406, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28573512, Length=202, Percent_Identity=40.5940594059406, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI45550449, Length=202, Percent_Identity=40.5940594059406, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_LACLA (Q9CF21)

Other databases:

- EMBL:   AE005176
- PIR:   D86832
- RefSeq:   NP_267816.1
- ProteinModelPortal:   Q9CF21
- SMR:   Q9CF21
- GeneID:   1115320
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L108994
- NMPDR:   fig|272623.1.peg.1702
- HOGENOM:   HBG527126
- OMA:   DQIGVIA
- ProtClustDB:   PRK05480
- BioCyc:   LLAC272623:L108994-MONOMER
- BRENDA:   2.7.1.48
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 23740; Mature: 23740

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDH
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEHHHHCCCCCC
PLAFDTDYLIAQLKELQYGRAVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERL
CCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHCCHHHHHHCCCEEEEECCEEEECCHHH
RDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQYLDAVKPMYHQFIEPTKRYAD
HHHEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIPEGVSNTVGVDIITTKIASILND
EECCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDH
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEHHHHCCCCCC
PLAFDTDYLIAQLKELQYGRAVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERL
CCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHCCHHHHHHCCCEEEEECCEEEECCHHH
RDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQYLDAVKPMYHQFIEPTKRYAD
HHHEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIPEGVSNTVGVDIITTKIASILND
EECCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471