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The map label for this gene is kdgK

Identifier: 15673609

GI number: 15673609

Start: 1672057

End: 1673007

Strand: Reverse

Name: kdgK

Synonym: L0021

Alternate gene names: 15673609

Gene position: 1673007-1672057 (Counterclockwise)

Preceding gene: 15673610

Following gene: 15673608

Centisome position: 70.72

GC content: 36.38

Gene sequence:

>951_bases
ATGACTGAATTTATAACACTTGGCGAACCTTTAGTCGTTCTTGCCTCAGAAAATCAAGATATAAGTTTAGATGTAGCTGA
GCATTTCAGCAAATATTTAGCTGGTGCGGAGCTAAATGTTGCGATTGGTTTGAGTCGTCTAGGACATAAAGGAATTTACC
TTTCTAAAGTCGGAGAGGATTCATTTGGGAATTTTATTATTGAATCAGTCAAAAAAGCGGAGATTGAAACGACCTATCTC
ACCAAAGATAAAAACTATTCAACAGGCTTTTATTTAAAACAAAAAGTAAGTGAGGGCGACCCAAAAGTTGATTATTATCG
CAAAAATTCTGCAGCGGCCAATTTATCCATTGCTGAACTAAAAGCTCTAGATTTATCAGGGATAAAAATTGCGCATCTCT
CAGGAATTTTTCCAGCCCTTTCAGAAACTAGTTTAAAAACTTTTCAAGCATTCAATCAAAAATTAAATGAAGCAGATATT
TTAACCATTTTCGATCCAAATTTACGACCTGTACTTTGGGATAATCAAGAAAAAATGATAAGAACAATCAATGATTTAGC
AAAGCAAAGTCAAATCATTCTGCCAGGAATAAATGAAGGTGAAATCTTGACCGGTTCATCCGAACCAGAAAAAATCGCTA
ATTTTTACCTTGAGCAAAGCCCTCTCACAAAGATTGTAGTTGTCAAATTAGGTGCTGACGGTGCTTTTGTAAAATTAAAA
AATGGTGAACAATATTTTGTTTCTGGATTTAAAGTAGCAAAAGTTGTTGATACGGTTGGAGCAGGAGACGGATTCGCCGT
TGGTCTTGAGTCTGCCTTACTTGAAGGAAAAACCTTAAAAGAAGCCGTCAAGCGTGCCTGTGCCGTTGGAGCATTAGCAG
TTCAAAGCTCAGGAGATAGTGAAGGTTATCCCACAAAAGAAGAATTAAAAGCATTTTACAAGGAGATGTAG

Upstream 100 bases:

>100_bases
TCCCTGATAATGAAGCACTTGTTGGAAAAATGATTGAAGATATTAGTTATAATAATGTGCATGATTATTTTGGATTTTTC
AAAGATGAGGACTCTAATCA

Downstream 100 bases:

>100_bases
TCATGCAAAGAGCAGAATTATTAAATAAAGTGATTCAATCAGGAGTCGTCTCGGTCGTCCGAGCTGAGAGTGGCGAAAAA
GCATTAAAAATCGTAGAAGC

Product: 2-dehydro-3-deoxygluconokinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTEFITLGEPLVVLASENQDISLDVAEHFSKYLAGAELNVAIGLSRLGHKGIYLSKVGEDSFGNFIIESVKKAEIETTYL
TKDKNYSTGFYLKQKVSEGDPKVDYYRKNSAAANLSIAELKALDLSGIKIAHLSGIFPALSETSLKTFQAFNQKLNEADI
LTIFDPNLRPVLWDNQEKMIRTINDLAKQSQIILPGINEGEILTGSSEPEKIANFYLEQSPLTKIVVVKLGADGAFVKLK
NGEQYFVSGFKVAKVVDTVGAGDGFAVGLESALLEGKTLKEAVKRACAVGALAVQSSGDSEGYPTKEELKAFYKEM

Sequences:

>Translated_316_residues
MTEFITLGEPLVVLASENQDISLDVAEHFSKYLAGAELNVAIGLSRLGHKGIYLSKVGEDSFGNFIIESVKKAEIETTYL
TKDKNYSTGFYLKQKVSEGDPKVDYYRKNSAAANLSIAELKALDLSGIKIAHLSGIFPALSETSLKTFQAFNQKLNEADI
LTIFDPNLRPVLWDNQEKMIRTINDLAKQSQIILPGINEGEILTGSSEPEKIANFYLEQSPLTKIVVVKLGADGAFVKLK
NGEQYFVSGFKVAKVVDTVGAGDGFAVGLESALLEGKTLKEAVKRACAVGALAVQSSGDSEGYPTKEELKAFYKEM
>Mature_315_residues
TEFITLGEPLVVLASENQDISLDVAEHFSKYLAGAELNVAIGLSRLGHKGIYLSKVGEDSFGNFIIESVKKAEIETTYLT
KDKNYSTGFYLKQKVSEGDPKVDYYRKNSAAANLSIAELKALDLSGIKIAHLSGIFPALSETSLKTFQAFNQKLNEADIL
TIFDPNLRPVLWDNQEKMIRTINDLAKQSQIILPGINEGEILTGSSEPEKIANFYLEQSPLTKIVVVKLGADGAFVKLKN
GEQYFVSGFKVAKVVDTVGAGDGFAVGLESALLEGKTLKEAVKRACAVGALAVQSSGDSEGYPTKEELKAFYKEM

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=289, Percent_Identity=27.681660899654, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87081971, Length=294, Percent_Identity=28.2312925170068, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082281, Length=303, Percent_Identity=24.7524752475248, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790193, Length=318, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 34376; Mature: 34244

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFITLGEPLVVLASENQDISLDVAEHFSKYLAGAELNVAIGLSRLGHKGIYLSKVGED
CCCEEECCCCEEEEECCCCCEEEHHHHHHHHHHCCCCEEEEEEHHHCCCCCEEEEECCCC
SFGNFIIESVKKAEIETTYLTKDKNYSTGFYLKQKVSEGDPKVDYYRKNSAAANLSIAEL
CHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCHHHH
KALDLSGIKIAHLSGIFPALSETSLKTFQAFNQKLNEADILTIFDPNLRPVLWDNQEKMI
EEECCCCEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCHHHHH
RTINDLAKQSQIILPGINEGEILTGSSEPEKIANFYLEQSPLTKIVVVKLGADGAFVKLK
HHHHHHHHCCEEEECCCCCCCEEECCCCHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEE
NGEQYFVSGFKVAKVVDTVGAGDGFAVGLESALLEGKTLKEAVKRACAVGALAVQSSGDS
CCCEEECCCCHHHHHHHHCCCCCCEEECHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCC
EGYPTKEELKAFYKEM
CCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TEFITLGEPLVVLASENQDISLDVAEHFSKYLAGAELNVAIGLSRLGHKGIYLSKVGED
CCEEECCCCEEEEECCCCCEEEHHHHHHHHHHCCCCEEEEEEHHHCCCCCEEEEECCCC
SFGNFIIESVKKAEIETTYLTKDKNYSTGFYLKQKVSEGDPKVDYYRKNSAAANLSIAEL
CHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCHHHH
KALDLSGIKIAHLSGIFPALSETSLKTFQAFNQKLNEADILTIFDPNLRPVLWDNQEKMI
EEECCCCEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCHHHHH
RTINDLAKQSQIILPGINEGEILTGSSEPEKIANFYLEQSPLTKIVVVKLGADGAFVKLK
HHHHHHHHCCEEEECCCCCCCEEECCCCHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEE
NGEQYFVSGFKVAKVVDTVGAGDGFAVGLESALLEGKTLKEAVKRACAVGALAVQSSGDS
CCCEEECCCCHHHHHHHHCCCCCCEEECHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCC
EGYPTKEELKAFYKEM
CCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]