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The map label for this gene is yleD

Identifier: 15673113

GI number: 15673113

Start: 1145519

End: 1146883

Strand: Direct

Name: yleD

Synonym: L145238

Alternate gene names: 15673113

Gene position: 1145519-1146883 (Clockwise)

Preceding gene: 15673112

Following gene: 15673114

Centisome position: 48.42

GC content: 39.85

Gene sequence:

>1365_bases
ATGGCAGAAGAAAAAATAGCTCGTATTGCACGTGAGATTTATGAAAATGTTGGTGGAACACAAAATGTAAAAAAATTGAT
TCTTTGCATGACTCGTGTTCGGATGACCATTATTGATGATTCAAAAGTTAACTTAGCTGGTTTAAAGGCAATTGATGGAG
TGATGGGTGTCGTTGAAGATGAAACACTACAAGTTGTCATCGGACCTGGAACTGTAAATAAAGTTGCTCAAGCAATGGTT
GAGACAGTTGGGGTAAGGTTAGGAGAAACTTTCCCAAGTGCTGAAGGTCAATCAATTGATGATTTAATGGCAAAAACAAA
ATCGGAAGCTAAAGAAAAGTATAATAAGCCTTCAAAATTTAAAGCGGTTCTTAATACGATTTCTAAAATATTCGTTCCAT
TGATTCCTGCTTTTGTTGGTGCCGGTTTGATTGGTGGGCTGGCCTCTGTTTTAGGAAACTTAGTCACTGCTGGTACCTTA
GATGCCGCAACATGGACCCAGTTTATTACCGTCTTAAAAATTATTCAATCCGGAATATTTTCTTACTTAGCCATCTATGT
CGGAATTAATTCAGCTCAAGAATTTGGAGCGACACCTTCGCTTGGTGGTGTTATCGGTGCGGTTTCCTTGCTCACAGGAA
TGAACCCAGAAGCACCATTGAAAAATATCTTTAATGGAAGTGCACTTTCGGCAGGACAAGGTGGAATTATTGGCGTAATT
TTCGCTGTTTGGTTACTATCGATTTTAGAAAAACAACTACGTAAATTTATTCCTGACTCAATTGATATTATTGTGACACC
AACCATTGGTTTATTGGTCATTGGTTTTGCGGAAATTTTTGCCATTATGCCGGTAGCGGGAGTTATTTCTTCAAGTTTAG
TCGGGGCAATTAACTTTATTCTTCAAGTTGGTGGTGGTTTCTCTGGCTTTGTTTTGGGTGTACTTTTCTTACCAATGGTT
ATGTTTGGTTTACACCAAATCTTAACCCCTATTCATTTAGAAATGATTGCTAAAACGTGCTCAACACAATTATTGCCAAT
CCTTGCAATGGCTGGAGCTGGTCAAGTTGGTGCTGCGATTGCGCTTTGGCTTCGTTTGAGAAAAGATAAAGAATTTGTCG
AACTTGTTAAAGGTGCTCTTCCAGTAGGAATTTTAGGAATTGGAGAACCTTTAATTTATGGGATTACCCTACCTCTTGGT
CGTCCATTCATCACGGCCTGTATCGGTGGGGGGATTGGTGGTGCAATCATCGGTTCATTAGGTCAAGCTGGAGCCATTGC
TATTGGCCCTTCAGGCCTTGCTCTCCTTCCACTTATTGCTAATGGCAAATGGTGGGTTTATCTTCTTGGACTATTGGGTG
CTTAA

Upstream 100 bases:

>100_bases
GCAGCAGAAGAAGGAAAAACCAAGCTTGTTAGAGCAAATGGTTTTGTGAAAAATACTCTGAATTAAGAATTTACCTTTTA
AGGTAGGAGAAGGAGCAAAA

Downstream 100 bases:

>100_bases
ATTGGTGGATTTATTGCTACTTATCTCTTTGGTATTCCTAAAGATGCAAAAGAAAAAGCAGATAATTATGGAAAATCAGT
CCAAATGGAAACTATTCAAC

Product: sucrose-specific PTS system IIBC component

Products: NA

Alternate protein names: Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAEEKIARIAREIYENVGGTQNVKKLILCMTRVRMTIIDDSKVNLAGLKAIDGVMGVVEDETLQVVIGPGTVNKVAQAMV
ETVGVRLGETFPSAEGQSIDDLMAKTKSEAKEKYNKPSKFKAVLNTISKIFVPLIPAFVGAGLIGGLASVLGNLVTAGTL
DAATWTQFITVLKIIQSGIFSYLAIYVGINSAQEFGATPSLGGVIGAVSLLTGMNPEAPLKNIFNGSALSAGQGGIIGVI
FAVWLLSILEKQLRKFIPDSIDIIVTPTIGLLVIGFAEIFAIMPVAGVISSSLVGAINFILQVGGGFSGFVLGVLFLPMV
MFGLHQILTPIHLEMIAKTCSTQLLPILAMAGAGQVGAAIALWLRLRKDKEFVELVKGALPVGILGIGEPLIYGITLPLG
RPFITACIGGGIGGAIIGSLGQAGAIAIGPSGLALLPLIANGKWWVYLLGLLGA

Sequences:

>Translated_454_residues
MAEEKIARIAREIYENVGGTQNVKKLILCMTRVRMTIIDDSKVNLAGLKAIDGVMGVVEDETLQVVIGPGTVNKVAQAMV
ETVGVRLGETFPSAEGQSIDDLMAKTKSEAKEKYNKPSKFKAVLNTISKIFVPLIPAFVGAGLIGGLASVLGNLVTAGTL
DAATWTQFITVLKIIQSGIFSYLAIYVGINSAQEFGATPSLGGVIGAVSLLTGMNPEAPLKNIFNGSALSAGQGGIIGVI
FAVWLLSILEKQLRKFIPDSIDIIVTPTIGLLVIGFAEIFAIMPVAGVISSSLVGAINFILQVGGGFSGFVLGVLFLPMV
MFGLHQILTPIHLEMIAKTCSTQLLPILAMAGAGQVGAAIALWLRLRKDKEFVELVKGALPVGILGIGEPLIYGITLPLG
RPFITACIGGGIGGAIIGSLGQAGAIAIGPSGLALLPLIANGKWWVYLLGLLGA
>Mature_453_residues
AEEKIARIAREIYENVGGTQNVKKLILCMTRVRMTIIDDSKVNLAGLKAIDGVMGVVEDETLQVVIGPGTVNKVAQAMVE
TVGVRLGETFPSAEGQSIDDLMAKTKSEAKEKYNKPSKFKAVLNTISKIFVPLIPAFVGAGLIGGLASVLGNLVTAGTLD
AATWTQFITVLKIIQSGIFSYLAIYVGINSAQEFGATPSLGGVIGAVSLLTGMNPEAPLKNIFNGSALSAGQGGIIGVIF
AVWLLSILEKQLRKFIPDSIDIIVTPTIGLLVIGFAEIFAIMPVAGVISSSLVGAINFILQVGGGFSGFVLGVLFLPMVM
FGLHQILTPIHLEMIAKTCSTQLLPILAMAGAGQVGAAIALWLRLRKDKEFVELVKGALPVGILGIGEPLIYGITLPLGR
PFITACIGGGIGGAIIGSLGQAGAIAIGPSGLALLPLIANGKWWVYLLGLLGA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788769, Length=454, Percent_Identity=36.5638766519824, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1790159, Length=424, Percent_Identity=30.4245283018868, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI2367362, Length=453, Percent_Identity=26.9315673289183, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI48994906, Length=436, Percent_Identity=27.2935779816514, Blast_Score=118, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 47211; Mature: 47080

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEEEECCCCCEEEHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AEEKIARIAREIYENVGGTQNVKKLILCMTRVRMTIIDDSKVNLAGLKAIDGVMGVVED
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCC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CCCCEEEECCCCCEEEHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA