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The map label for this gene is yleE

Identifier: 15673114

GI number: 15673114

Start: 1146884

End: 1147471

Strand: Direct

Name: yleE

Synonym: L146642

Alternate gene names: 15673114

Gene position: 1146884-1147471 (Clockwise)

Preceding gene: 15673113

Following gene: 15673115

Centisome position: 48.48

GC content: 36.05

Gene sequence:

>588_bases
ATTGGTGGATTTATTGCTACTTATCTCTTTGGTATTCCTAAAGATGCAAAAGAAAAAGCAGATAATTATGGAAAATCAGT
CCAAATGGAAACTATTCAACCTACTTTACGTGTTGTGACAACTCCAGAATTTTCTAGTTCAACAATCGCATCACCACTTG
AGGGGAATGTGAAAGAACTTTCTACAATTGAGGATGAAGTTTTCTCAAGCGGAATGTTGGGTAAAGGAGTAGCCATTGAA
CCAGATAATGGAGATGTCGTTTCGCCCGTCGCTGGAGTTGTTACTACAGTTTTTCCAACTAAGCACGCGATTGGTTTGAC
TAGTGATGACGGTGTTGAAATTCTTATTCATATTGGAATGGATACTGTTGGCTTAAATGGTGAAGCTTTTGAAAGTTTCG
TTAAGCAAAATGACCGTGTCAAAAAAGGAGATTTACTGGTAAGAGCAGATCTTTCAAAAATAAAAGCGGCAGGTTTATCT
ATAATTACACCTGTGGTTATCACAAATTCTGATACTTATCGAAAAATTATTATCAGTCATGGTGGGAAAATAAGTAAAGG
TCAAGAGATTATAACAGTAAAAGCATAA

Upstream 100 bases:

>100_bases
AGCTGGAGCCATTGCTATTGGCCCTTCAGGCCTTGCTCTCCTTCCACTTATTGCTAATGGCAAATGGTGGGTTTATCTTC
TTGGACTATTGGGTGCTTAA

Downstream 100 bases:

>100_bases
AAGTTAGAGGTTGGTTTATACCAACCTCTTTGTTATAATTAAAGAAGAACGGAGAGGTTAAATGGATACTTTACTTATCA
TTAGGCAAAATTATTCTAGC

Product: hypothetical protein

Products: NA

Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MGGFIATYLFGIPKDAKEKADNYGKSVQMETIQPTLRVVTTPEFSSSTIASPLEGNVKELSTIEDEVFSSGMLGKGVAIE
PDNGDVVSPVAGVVTTVFPTKHAIGLTSDDGVEILIHIGMDTVGLNGEAFESFVKQNDRVKKGDLLVRADLSKIKAAGLS
IITPVVITNSDTYRKIIISHGGKISKGQEIITVKA

Sequences:

>Translated_195_residues
MGGFIATYLFGIPKDAKEKADNYGKSVQMETIQPTLRVVTTPEFSSSTIASPLEGNVKELSTIEDEVFSSGMLGKGVAIE
PDNGDVVSPVAGVVTTVFPTKHAIGLTSDDGVEILIHIGMDTVGLNGEAFESFVKQNDRVKKGDLLVRADLSKIKAAGLS
IITPVVITNSDTYRKIIISHGGKISKGQEIITVKA
>Mature_194_residues
GGFIATYLFGIPKDAKEKADNYGKSVQMETIQPTLRVVTTPEFSSSTIASPLEGNVKELSTIEDEVFSSGMLGKGVAIEP
DNGDVVSPVAGVVTTVFPTKHAIGLTSDDGVEILIHIGMDTVGLNGEAFESFVKQNDRVKKGDLLVRADLSKIKAAGLSI
ITPVVITNSDTYRKIIISHGGKISKGQEIITVKA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=159, Percent_Identity=44.6540880503145, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1786894, Length=144, Percent_Identity=38.8888888888889, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1788757, Length=129, Percent_Identity=38.7596899224806, Blast_Score=104, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011297 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 20663; Mature: 20532

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGFIATYLFGIPKDAKEKADNYGKSVQMETIQPTLRVVTTPEFSSSTIASPLEGNVKEL
CCCHHEEHHHCCCCHHHHHHHHCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHH
STIEDEVFSSGMLGKGVAIEPDNGDVVSPVAGVVTTVFPTKHAIGLTSDDGVEILIHIGM
HHHHHHHHHCCCCCCCEEEECCCCCEECHHHHHHHHHCCCCCEECCCCCCCEEEEEEECC
DTVGLNGEAFESFVKQNDRVKKGDLLVRADLSKIKAAGLSIITPVVITNSDTYRKIIISH
CEECCCHHHHHHHHHCCCCCCCCCEEEEECHHHHHHCCCEEEEEEEEECCCCCEEEEEEC
GGKISKGQEIITVKA
CCCCCCCCEEEEEEC
>Mature Secondary Structure 
GGFIATYLFGIPKDAKEKADNYGKSVQMETIQPTLRVVTTPEFSSSTIASPLEGNVKEL
CCHHEEHHHCCCCHHHHHHHHCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHH
STIEDEVFSSGMLGKGVAIEPDNGDVVSPVAGVVTTVFPTKHAIGLTSDDGVEILIHIGM
HHHHHHHHHCCCCCCCEEEECCCCCEECHHHHHHHHHCCCCCEECCCCCCCEEEEEEECC
DTVGLNGEAFESFVKQNDRVKKGDLLVRADLSKIKAAGLSIITPVVITNSDTYRKIIISH
CEECCCHHHHHHHHHCCCCCCCCCEEEEECHHHHHHCCCEEEEEEEEECCCCCEEEEEEC
GGKISKGQEIITVKA
CCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377; 8628237 [H]