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The map label for this gene is ptsH

Identifier: 15835231

GI number: 15835231

Start: 738793

End: 739107

Strand: Reverse

Name: ptsH

Synonym: TC0614

Alternate gene names: 15835231

Gene position: 739107-738793 (Counterclockwise)

Preceding gene: 15835233

Following gene: 15835230

Centisome position: 68.89

GC content: 39.05

Gene sequence:

>315_bases
ATGAGCGGTGGGGATGATTTAGTTCTTCATAATCCTGTAGAGGATGGAGAACTCTCTGCTATTTTCATGATACGAAACCC
TTCAGGAATACATGTACGTCCGGCAGGAACTATTGTTAAATTATTTGATGGCGAAGATTGTGAAGCAACTTTCACTTATT
TAGGAAAAACAGTGAATGCTAGGAGTGTCATGAGTATTCTTATGTTAGGAGCTTCTTATAATGGAGAGATCACTGTGCGA
ATAAAAGGCCCTTCGGCTTCTCGTGTAATGCAAAAACTAGCAGAGGTTTTTAATTCTGGATTCGGAGAGTTATAA

Upstream 100 bases:

>100_bases
TAAGGCTATTGAAAATAGACTCTAAGTACTGATTATCATATCTTTTTGATTGGATTTATCTTACTATCGTTTTGTTTTTA
TAAGCACAGGGAAGAATGCT

Downstream 100 bases:

>100_bases
ATGGGCGCTACGAGTCAAAAGGAATTGCAGCAAGAGTTTGTGATTGTAGGAGAGCCTGTTGTTCCTGGAATAGGATTGGG
TAAATCTTTATTGCTAGGAA

Product: phosphocarrier protein HPr

Products: fructose-6-phosphate [Cytoplasm]; pyruvate; fructose-1-phosphate [Cytoplasm] [C]

Alternate protein names: Histidine-containing protein

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MSGGDDLVLHNPVEDGELSAIFMIRNPSGIHVRPAGTIVKLFDGEDCEATFTYLGKTVNARSVMSILMLGASYNGEITVR
IKGPSASRVMQKLAEVFNSGFGEL

Sequences:

>Translated_104_residues
MSGGDDLVLHNPVEDGELSAIFMIRNPSGIHVRPAGTIVKLFDGEDCEATFTYLGKTVNARSVMSILMLGASYNGEITVR
IKGPSASRVMQKLAEVFNSGFGEL
>Mature_103_residues
SGGDDLVLHNPVEDGELSAIFMIRNPSGIHVRPAGTIVKLFDGEDCEATFTYLGKTVNARSVMSILMLGASYNGEITVRI
KGPSASRVMQKLAEVFNSGFGEL

Specific function: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their tr

COG id: COG1925

COG function: function code G; Phosphotransferase system, HPr-related proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPr domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTHP_CHLMU (Q9PK56)

Other databases:

- EMBL:   AE002160
- PIR:   G81682
- RefSeq:   NP_296990.1
- ProteinModelPortal:   Q9PK56
- SMR:   Q9PK56
- GeneID:   1245976
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0614
- TIGR:   TC_0614
- HOGENOM:   HBG653254
- OMA:   APQNGEI
- ProtClustDB:   CLSK871321
- BioCyc:   CMUR243161:TC_0614-MONOMER
- GO:   GO:0005737
- InterPro:   IPR005698
- InterPro:   IPR000032
- InterPro:   IPR002114
- Gene3D:   G3DSA:3.30.1340.10
- PRINTS:   PR00107
- TIGRFAMs:   TIGR01003

Pfam domain/function: PF00381 PTS-HPr; SSF55594 HPr_protein

EC number: 2.7.1.69 [C]

Molecular weight: Translated: 11148; Mature: 11017

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS51350 PTS_HPR_DOM; PS00369 PTS_HPR_HIS; PS00589 PTS_HPR_SER

Important sites: ACT_SITE 31-31

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGDDLVLHNPVEDGELSAIFMIRNPSGIHVRPAGTIVKLFDGEDCEATFTYLGKTVNA
CCCCCCEEEECCCCCCCEEEEEEEECCCCEEEECCCCEEEEECCCCCCEEEEECCCCCCH
RSVMSILMLGASYNGEITVRIKGPSASRVMQKLAEVFNSGFGEL
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SGGDDLVLHNPVEDGELSAIFMIRNPSGIHVRPAGTIVKLFDGEDCEATFTYLGKTVNA
CCCCCEEEECCCCCCCEEEEEEEECCCCEEEECCCCEEEEECCCCCCEEEEECCCCCCH
RSVMSILMLGASYNGEITVRIKGPSASRVMQKLAEVFNSGFGEL
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fructose [Periplasm]; phosphoenolpyruvate [C]

Specific reaction: phosphoenolpyruvate + fructose [Periplasm] = fructose-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + fructose [Periplasm] = fructose-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935