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Identifier: 15835171

GI number: 15835171

Start: 662290

End: 663024

Strand: Direct

Name: Not Available

Synonym: TC0553

Alternate gene names: 15835171

Gene position: 662290-663024 (Clockwise)

Preceding gene: 15835170

Following gene: 15835176

Centisome position: 61.73

GC content: 39.05

Gene sequence:

>735_bases
ATGTGGTTAGGAGACTATTCTTTAATAAATCTCTTAGGCATCTTTTTGCAAGCCACCTTTATCCAAAATATTTTGCTTTC
CACATTTTTAGGGATGTGCAGCTATTTAGCCTGTTCTTCTCGCTTGTCAACAGCCAACGGCTTAGGGATGTCTGTAGCTC
TCGTACTTACCATTACAGGAAGTATTAACTGGTTGATCCACCATTTTGTCACAGGGCCTCATGCCTTATCCTGGCTATCT
CCTGCATTAGCAAATATAGATCTCAGCTTTTTAGAATTGATTACATTTATTGTTGTTATCGCAGCATTCACACAAATTTT
AGAGCTCCTTCTGGAGCGATTTTCAAGAAACCTCTATTTAGCTTTAGGAATCTTTCTACCCCTTATTGCAGTAAACTGTG
CTATTTTAGGCGGAGTATTATTTGGAATTACCCGAAACTATCCTTTTCTTCCTATGGTTGTATTTTCTTTAGGATCAGGA
TGTGGTTGGTGGTTAGCTATTGTTCTCTTTGCAACCATTAGAGAAAAGTTAGCCTATTCCGATATCCCTCAACATTTACA
AGGAATGGGGATCTCCTTCATTACAACAGGCCTTATAGCTATGGCATTCATGGGATTAACAGGAATTGACATCTCAAAAC
CTACAGCTAAATCTGTAGTGATTTCAGACACTTCCACCAATAAATCAAAAACAACCTCCGCGCAAGAACGCCTCAGCTCA
AACCACAAAGCTTAA

Upstream 100 bases:

>100_bases
CTTAGGGTTGATGGTTTTAGCTCCATCAGCATTTTTCCTATTAGGAATCATGGTTTGGCTGGTGAATATTGTTAGAGCTT
CAAAGACAAAGAGGTAACAT

Downstream 100 bases:

>100_bases
ACTACAGGGCAAAGCGTAAACAAACCCTAAGGATCTAGGGAAAAGCGCTCTCCATCGAAATCTTCTGACAATTGCAGAAC
AACGAACCAGCCCTCGGATT

Product: Na(+)-translocating NADH-quinone reductase subunit E

Products: NA

Alternate protein names: Na(+)-NQR subunit E; Na(+)-translocating NQR subunit E; NQR complex subunit E; NQR-1 subunit E

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MWLGDYSLINLLGIFLQATFIQNILLSTFLGMCSYLACSSRLSTANGLGMSVALVLTITGSINWLIHHFVTGPHALSWLS
PALANIDLSFLELITFIVVIAAFTQILELLLERFSRNLYLALGIFLPLIAVNCAILGGVLFGITRNYPFLPMVVFSLGSG
CGWWLAIVLFATIREKLAYSDIPQHLQGMGISFITTGLIAMAFMGLTGIDISKPTAKSVVISDTSTNKSKTTSAQERLSS
NHKA

Sequences:

>Translated_244_residues
MWLGDYSLINLLGIFLQATFIQNILLSTFLGMCSYLACSSRLSTANGLGMSVALVLTITGSINWLIHHFVTGPHALSWLS
PALANIDLSFLELITFIVVIAAFTQILELLLERFSRNLYLALGIFLPLIAVNCAILGGVLFGITRNYPFLPMVVFSLGSG
CGWWLAIVLFATIREKLAYSDIPQHLQGMGISFITTGLIAMAFMGLTGIDISKPTAKSVVISDTSTNKSKTTSAQERLSS
NHKA
>Mature_244_residues
MWLGDYSLINLLGIFLQATFIQNILLSTFLGMCSYLACSSRLSTANGLGMSVALVLTITGSINWLIHHFVTGPHALSWLS
PALANIDLSFLELITFIVVIAAFTQILELLLERFSRNLYLALGIFLPLIAVNCAILGGVLFGITRNYPFLPMVVFSLGSG
CGWWLAIVLFATIREKLAYSDIPQHLQGMGISFITTGLIAMAFMGLTGIDISKPTAKSVVISDTSTNKSKTTSAQERLSS
NHKA

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG2209

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787914, Length=205, Percent_Identity=36.5853658536585, Blast_Score=133, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRE_CHLMU (Q9PKB3)

Other databases:

- EMBL:   AE002160
- PIR:   E81690
- RefSeq:   NP_296930.1
- GeneID:   1245913
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0553
- TIGR:   TC_0553
- HOGENOM:   HBG624915
- OMA:   FLGMCSF
- PhylomeDB:   Q9PKB3
- ProtClustDB:   PRK01061
- BioCyc:   CMUR243161:TC_0553-MONOMER
- HAMAP:   MF_00429
- InterPro:   IPR003667
- InterPro:   IPR010967
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01940

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 26467; Mature: 26467

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcd4e20c)-; HASH(0xc6095dc)-; HASH(0xc57a504)-; HASH(0xcba23d8)-; HASH(0xca057d8)-; HASH(0xbce6e18)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLGDYSLINLLGIFLQATFIQNILLSTFLGMCSYLACSSRLSTANGLGMSVALVLTITG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
SINWLIHHFVTGPHALSWLSPALANIDLSFLELITFIVVIAAFTQILELLLERFSRNLYL
HHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ALGIFLPLIAVNCAILGGVLFGITRNYPFLPMVVFSLGSGCGWWLAIVLFATIREKLAYS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DIPQHLQGMGISFITTGLIAMAFMGLTGIDISKPTAKSVVISDTSTNKSKTTSAQERLSS
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
NHKA
CCCH
>Mature Secondary Structure
MWLGDYSLINLLGIFLQATFIQNILLSTFLGMCSYLACSSRLSTANGLGMSVALVLTITG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
SINWLIHHFVTGPHALSWLSPALANIDLSFLELITFIVVIAAFTQILELLLERFSRNLYL
HHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ALGIFLPLIAVNCAILGGVLFGITRNYPFLPMVVFSLGSGCGWWLAIVLFATIREKLAYS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DIPQHLQGMGISFITTGLIAMAFMGLTGIDISKPTAKSVVISDTSTNKSKTTSAQERLSS
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
NHKA
CCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10684935