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Identifier: 15835170

GI number: 15835170

Start: 661645

End: 662286

Strand: Direct

Name: Not Available

Synonym: TC0552

Alternate gene names: 15835170

Gene position: 661645-662286 (Clockwise)

Preceding gene: 15835169

Following gene: 15835171

Centisome position: 61.67

GC content: 38.94

Gene sequence:

>642_bases
ATGACAACCAATAAATCCTCTTTAAGCTACTTTACTGATGCTTTGTGGATCAATAACCAGCCTCTCGTCGCTATTCTAGG
GATCTGTTCAGCTCTTGCTGTTACCACCACAGTAACAACGGCTTTAACAATGGGATTAGCCGTTAGCTTTGTTACCGGAT
TCGCTTCTTTTGTTGTATCTTTACTAAGAAAAATTACTCCAGAAAGCGTTCGAATGATCGCTCAGCTTATCATCATTAGC
CTTTTTGTGATCCTTATCGACCAATTTTTAAAAGCCTTTTTTTTCAATATTTCCAAAACGCTTTCTGTTTTTGTTGGTCT
AATCATTACTAACTGTATTGTCATGGGACGAGCAGAAAGTATGGCTAGACATATTTCTCCTATTCCTGCGTTTTTAGATG
GTCTGGGATCGGGACTTGGATATGGGTGGGTTCTTGTTTGCATCAGTATCATTAGAGAGTTATTCGGGTTTGGAACCATT
TTAGGCTTCCACATCATTCCTAAGATTTTTTATGCTTCAGCAGCTCACCCCGATGGATATGAAAACTTAGGGTTGATGGT
TTTAGCTCCATCAGCATTTTTCCTATTAGGAATCATGGTTTGGCTGGTGAATATTGTTAGAGCTTCAAAGACAAAGAGGT
AA

Upstream 100 bases:

>100_bases
CTGACCTGTAATGGAGTTACTGAAGCTTTTGCTAATTCGCTAGCTCCTTACCGCCCCTTATTGACTTTCTTCGCCAATCT
TAACTCTAGTGGAGAATCTC

Downstream 100 bases:

>100_bases
CATATGTGGTTAGGAGACTATTCTTTAATAAATCTCTTAGGCATCTTTTTGCAAGCCACCTTTATCCAAAATATTTTGCT
TTCCACATTTTTAGGGATGT

Product: Na(+)-translocating NADH-quinone reductase subunit D

Products: NA

Alternate protein names: Na(+)-NQR subunit D; Na(+)-translocating NQR subunit D; NQR complex subunit D; NQR-1 subunit D

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTTNKSSLSYFTDALWINNQPLVAILGICSALAVTTTVTTALTMGLAVSFVTGFASFVVSLLRKITPESVRMIAQLIIIS
LFVILIDQFLKAFFFNISKTLSVFVGLIITNCIVMGRAESMARHISPIPAFLDGLGSGLGYGWVLVCISIIRELFGFGTI
LGFHIIPKIFYASAAHPDGYENLGLMVLAPSAFFLLGIMVWLVNIVRASKTKR

Sequences:

>Translated_213_residues
MTTNKSSLSYFTDALWINNQPLVAILGICSALAVTTTVTTALTMGLAVSFVTGFASFVVSLLRKITPESVRMIAQLIIIS
LFVILIDQFLKAFFFNISKTLSVFVGLIITNCIVMGRAESMARHISPIPAFLDGLGSGLGYGWVLVCISIIRELFGFGTI
LGFHIIPKIFYASAAHPDGYENLGLMVLAPSAFFLLGIMVWLVNIVRASKTKR
>Mature_212_residues
TTNKSSLSYFTDALWINNQPLVAILGICSALAVTTTVTTALTMGLAVSFVTGFASFVVSLLRKITPESVRMIAQLIIISL
FVILIDQFLKAFFFNISKTLSVFVGLIITNCIVMGRAESMARHISPIPAFLDGLGSGLGYGWVLVCISIIRELFGFGTIL
GFHIIPKIFYASAAHPDGYENLGLMVLAPSAFFLLGIMVWLVNIVRASKTKR

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1347

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787919, Length=193, Percent_Identity=35.7512953367876, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRD_CHLMU (Q9PKB4)

Other databases:

- EMBL:   AE002160
- PIR:   D81690
- RefSeq:   NP_296929.1
- GeneID:   1245912
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0552
- TIGR:   TC_0552
- HOGENOM:   HBG624915
- OMA:   GGWYVPN
- PhylomeDB:   Q9PKB4
- ProtClustDB:   PRK09292
- BioCyc:   CMUR243161:TC_0552-MONOMER
- HAMAP:   MF_00428
- InterPro:   IPR003667
- InterPro:   IPR011292
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01939

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 23146; Mature: 23015

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc5f8dec)-; HASH(0xd0a0824)-; HASH(0xcd820e0)-; HASH(0xc13ead8)-; HASH(0xca8dabc)-; HASH(0xcc07c40)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNKSSLSYFTDALWINNQPLVAILGICSALAVTTTVTTALTMGLAVSFVTGFASFVVS
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRKITPESVRMIAQLIIISLFVILIDQFLKAFFFNISKTLSVFVGLIITNCIVMGRAES
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
MARHISPIPAFLDGLGSGLGYGWVLVCISIIRELFGFGTILGFHIIPKIFYASAAHPDGY
HHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ENLGLMVLAPSAFFLLGIMVWLVNIVRASKTKR
CCCCHHEEHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
TTNKSSLSYFTDALWINNQPLVAILGICSALAVTTTVTTALTMGLAVSFVTGFASFVVS
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRKITPESVRMIAQLIIISLFVILIDQFLKAFFFNISKTLSVFVGLIITNCIVMGRAES
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
MARHISPIPAFLDGLGSGLGYGWVLVCISIIRELFGFGTILGFHIIPKIFYASAAHPDGY
HHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ENLGLMVLAPSAFFLLGIMVWLVNIVRASKTKR
CCCCHHEEHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10684935