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The map label for this gene is clpC

Identifier: 15835176

GI number: 15835176

Start: 668059

End: 670671

Strand: Direct

Name: clpC

Synonym: TC0559

Alternate gene names: 15835176

Gene position: 668059-670671 (Clockwise)

Preceding gene: 15835171

Following gene: 15835178

Centisome position: 62.26

GC content: 40.91

Gene sequence:

>2613_bases
ATGTCGTATATGCTGAAGAGTATTCCACCTCGCCATATTCAGGTTTTTATGTTTGAGAAGTTTACCAATCGCGCAAAGCA
AGTGATTAAGTTGGCGAAAAAAGAAGCTCAACGACTCAATCACAACTATCTAGGAACCGAGCACATCTTATTGGGATTAC
TAAAACTAGGCCAAGGAGTGGCTGTTAATGTATTACGCACTCTTGGCGTTGACTTCGACACAGCAAAAAACGAAGTAGAA
AGACTCATTGGGTATGGACCGGAGATCCAAGTGTATGGAGATCCAGCTCTAACAGGTAGAGTGAAAAAATCTTTTGAATC
AGCTAATGAAGAAGCCTCTATTTTAGAACACAACTATGTCGGAACAGAACATCTTTTACTCGGAATTCTCAATCAAGCTG
ATGGTGTGGCTCTGCAAGTTTTAGAAAACTTGCATATAGATCCTAAAGAAATCCGAAAGGAAATTTTAAAAGAGCTAGAA
ACGTTTAATTTGCAGCTCCCTCCTTCTTCCTCTATTACCCCAAGAAACACGAATAGTTCTTCGTCTTCCTCTTCAAAATC
TTCTTCTTTAGGAGGACATTCTTTAGGTGGGGATAAACCTGAAAAGCTTTCCGCTCTCAAAGCGTATGGATATGACCTAA
CAGAAATGTTCAAAGAGGCTCGTCTAGATCCCGTTATTGGTCGATCTGCAGAAGTCGAACGATTAATTTTGATCCTTTGT
CGTCGTAGAAAAAACAACCCAGTTTTAATTGGAGAAGCTGGTGTAGGTAAAACAGCTATCGTTGAAGGATTAGCCCAAAA
AATTGTCTCTGGAGAAGTTCCTGAAGCTCTTCGTAAAAAACGATTGATCACCTTAGATTTGGCTCTGATGATAGCTGGAA
CCAAATATCGAGGTCAATTTGAAGAACGAATCAAAGCAGTTATGGATGAAGTCCGTAAGCATGGCAATATTCTTCTTTTC
ATTGATGAGCTTCACACCATTGTTGGCGCAGGGGCTGCTGAAGGAGCGATAGATGCTTCCCATATTTTGAAACCAGCCTT
AGCTCGTGGAGAAATTCAGTGCATAGGGGCTACAACTCTAGATGAATATCGAAAACACATTGAAAAAGATGCTGCTTTGG
AACGTCGATTCCAAAAAATTGTTGTTCAACCACCCAGTGTTGATGAGACTGTAGAAATTCTTAGAGGCCTGAAGAAAAAA
TATGAAGAGCATCATAATGTCTTCATCACCGATGAAGCTCTCGTTGCTGCTGCTAAACTATCCGACCAATACGTTCACGG
TCGCTTTCTTCCCGACAAAGCTATTGACCTTTTAGATGAAGCTGGAGCTCGTGTACGTGTCAATACAATGGGGCAACCTT
CGGAGCTTTTACGTTTAGAAGCTGAAATAGAAAGCACCAAACAGGCTAAAGAACAGGCTATAGGAACTCAAGAATATGAG
AAAGCTGCCAGCCTTCGTGATGAAGAGAAAAAGCTTAGAGAAAAACTAAGCAACATGAAACAACAGTGGGAATCAAATAA
AGAAGAACATCAAGTTCCTGTTGATGAGGAAGCTGTTGCTCAAGTGGTTTCAGTACAAACTGGTATTCCTGCGGCTCGCT
TAACAGAAGCAGAAAGCGAAAAATTATTAATGCTAGAGAATACTCTACAAAAGAAAGTAATTGGCCAAGATCAAGCTGTT
GCTAGTATTTGTCGAGCTATTCGTCGTTCAAGAACTGGCATTAAAGATCCTAATAGACCTATGGGATCCTTCCTATTTCT
AGGTCCTACTGGAGTTGGGAAAACTTTGCTAGCTCAACAAATTGCTGTTGAAATGTTTGGAGGAGAAGATTCTCTTATCC
AAGTAGATATGTCCGAATATATGGAGAAGTTTGCTGCGACCAAAATGATGGGATCTCCTCCAGGATATGTAGGTCACGAA
GAAGGCGGACATTTGACAGAACAGGTTCGCCGTCGCCCTTATTGTGTTGTTCTCTTTGATGAAATTGAGAAAGCTCATCC
AGATATTATGGATCTTATGTTGCAGATTCTTGAACAGGGCCGTCTAACGGATTCCTTTGGACGCAAGATTGATTTCCGTA
ATACCATTATTATTATGACTTCCAATTTGGGAGCTGATTTAATTCGGAAGACTGGAGAGATAGGTTTTGGTCTTCGTTCC
CATATGGATTATGGAGTGATCAAAGAGAAAATAGATGCTGCAGTCAAAAAGCATCTAAAACCAGAATTTATCAACCGTCT
AGATGAAAGTGTTATCTTTAAACCTCTTGAGAAGGAAGCCCTTTCTGAAATTATTCATCTAGAAATTAATAAACTGGGAT
CTCGTCTACAAAACCACCAAATGGCTCTTAATATTCCTGATTCGGTGGTCTCATTCTTGGTAGATAAAGGACATTCTCCA
GAAATGGGCGCCCGACCATTAAGACGTGTAGTGGAGCAGTACTTGGAAGATCCTTTAGCAGAGATGCTATTGAAAGAGTC
GTGCCGACAAGAAGCAAGAAAATTATGCGCTCGCCTAATAGAAGAGCGTGTTATTTTCGAGCGGGAAGACGAAATTTCTG
CTTTAGCTGTAGAGGGGGATGGCCCCGCCTCTGTTACAGCTGATGAATCATAG

Upstream 100 bases:

>100_bases
CTAGTCCCCTAGCAAAGATACCCAAACATCAAAAAAAATTTATTACAAAAAAACGCTACGCCACACCCCCTCTTTACGAA
AAGTTGCATCATTATCATAA

Downstream 100 bases:

>100_bases
GCACGGCAATTACTCCTCCTCCTAAACAAACGTCCCCCTGGTAAAAGGCTACTGTCTGTCCAGGGGTGACGGCTTTCACG
GGGATATCGAATACCACTTG

Product: ATP-dependent Clp protease, ATP-binding subunit ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 870; Mature: 869

Protein sequence:

>870_residues
MSYMLKSIPPRHIQVFMFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRTLGVDFDTAKNEVE
RLIGYGPEIQVYGDPALTGRVKKSFESANEEASILEHNYVGTEHLLLGILNQADGVALQVLENLHIDPKEIRKEILKELE
TFNLQLPPSSSITPRNTNSSSSSSSKSSSLGGHSLGGDKPEKLSALKAYGYDLTEMFKEARLDPVIGRSAEVERLILILC
RRRKNNPVLIGEAGVGKTAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLF
IDELHTIVGAGAAEGAIDASHILKPALARGEIQCIGATTLDEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKK
YEEHHNVFITDEALVAAAKLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSELLRLEAEIESTKQAKEQAIGTQEYE
KAASLRDEEKKLREKLSNMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESEKLLMLENTLQKKVIGQDQAV
ASICRAIRRSRTGIKDPNRPMGSFLFLGPTGVGKTLLAQQIAVEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHE
EGGHLTEQVRRRPYCVVLFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKTGEIGFGLRS
HMDYGVIKEKIDAAVKKHLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNHQMALNIPDSVVSFLVDKGHSP
EMGARPLRRVVEQYLEDPLAEMLLKESCRQEARKLCARLIEERVIFEREDEISALAVEGDGPASVTADES

Sequences:

>Translated_870_residues
MSYMLKSIPPRHIQVFMFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRTLGVDFDTAKNEVE
RLIGYGPEIQVYGDPALTGRVKKSFESANEEASILEHNYVGTEHLLLGILNQADGVALQVLENLHIDPKEIRKEILKELE
TFNLQLPPSSSITPRNTNSSSSSSSKSSSLGGHSLGGDKPEKLSALKAYGYDLTEMFKEARLDPVIGRSAEVERLILILC
RRRKNNPVLIGEAGVGKTAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLF
IDELHTIVGAGAAEGAIDASHILKPALARGEIQCIGATTLDEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKK
YEEHHNVFITDEALVAAAKLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSELLRLEAEIESTKQAKEQAIGTQEYE
KAASLRDEEKKLREKLSNMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESEKLLMLENTLQKKVIGQDQAV
ASICRAIRRSRTGIKDPNRPMGSFLFLGPTGVGKTLLAQQIAVEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHE
EGGHLTEQVRRRPYCVVLFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKTGEIGFGLRS
HMDYGVIKEKIDAAVKKHLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNHQMALNIPDSVVSFLVDKGHSP
EMGARPLRRVVEQYLEDPLAEMLLKESCRQEARKLCARLIEERVIFEREDEISALAVEGDGPASVTADES
>Mature_869_residues
SYMLKSIPPRHIQVFMFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRTLGVDFDTAKNEVER
LIGYGPEIQVYGDPALTGRVKKSFESANEEASILEHNYVGTEHLLLGILNQADGVALQVLENLHIDPKEIRKEILKELET
FNLQLPPSSSITPRNTNSSSSSSSKSSSLGGHSLGGDKPEKLSALKAYGYDLTEMFKEARLDPVIGRSAEVERLILILCR
RRKNNPVLIGEAGVGKTAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFI
DELHTIVGAGAAEGAIDASHILKPALARGEIQCIGATTLDEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKKY
EEHHNVFITDEALVAAAKLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSELLRLEAEIESTKQAKEQAIGTQEYEK
AASLRDEEKKLREKLSNMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESEKLLMLENTLQKKVIGQDQAVA
SICRAIRRSRTGIKDPNRPMGSFLFLGPTGVGKTLLAQQIAVEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHEE
GGHLTEQVRRRPYCVVLFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKTGEIGFGLRSH
MDYGVIKEKIDAAVKKHLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNHQMALNIPDSVVSFLVDKGHSPE
MGARPLRRVVEQYLEDPLAEMLLKESCRQEARKLCARLIEERVIFEREDEISALAVEGDGPASVTADES

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain

Homologues:

Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=37.4581939799331, Blast_Score=193, Evalue=6e-49,
Organism=Escherichia coli, GI1788943, Length=699, Percent_Identity=47.7825464949928, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=803, Percent_Identity=36.1145703611457, Blast_Score=470, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6320464, Length=702, Percent_Identity=44.3019943019943, Blast_Score=573, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6323002, Length=889, Percent_Identity=35.9955005624297, Blast_Score=510, Evalue=1e-145,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CLPC_CHLMU (Q9PKA8)

Other databases:

- EMBL:   AE002160
- PIR:   B81689
- RefSeq:   NP_296935.1
- ProteinModelPortal:   Q9PKA8
- SMR:   Q9PKA8
- GeneID:   1245918
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0559
- TIGR:   TC_0559
- HOGENOM:   HBG413133
- OMA:   VSRILFD
- ProtClustDB:   CLSK871304
- BioCyc:   CMUR243161:TC_0559-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943
- Gene3D:   G3DSA:1.10.1780.10
- PRINTS:   PR00300
- SMART:   SM00382

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR

EC number: NA

Molecular weight: Translated: 97009; Mature: 96878

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50151 UVR; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYMLKSIPPRHIQVFMFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGV
CCCCHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCH
AVNVLRTLGVDFDTAKNEVERLIGYGPEIQVYGDPALTGRVKKSFESANEEASILEHNYV
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHCCC
GTEHLLLGILNQADGVALQVLENLHIDPKEIRKEILKELETFNLQLPPSSSITPRNTNSS
CHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCC
SSSSSKSSSLGGHSLGGDKPEKLSALKAYGYDLTEMFKEARLDPVIGRSAEVERLILILC
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RRRKNNPVLIGEAGVGKTAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQF
HCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHEEHHHHHHCCCCCCHH
EERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAIDASHILKPALARGEIQCIGATTL
HHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCHH
DEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKKYEEHHNVFITDEALVAAAKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHH
SDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSELLRLEAEIESTKQAKEQAIGTQEYE
HHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KAASLRDEEKKLREKLSNMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESE
HHHHCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCC
KLLMLENTLQKKVIGQDQAVASICRAIRRSRTGIKDPNRPMGSFLFLGPTGVGKTLLAQQ
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHH
IAVEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLFD
HHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEEH
EIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKTGEIGFGLRS
HHHHHCCHHHHHHHHHHHCCCCCHHHCCEEECCCEEEEEECCCCHHHHHHCCCCCCCHHH
HMDYGVIKEKIDAAVKKHLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNHQ
HCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
MALNIPDSVVSFLVDKGHSPEMGARPLRRVVEQYLEDPLAEMLLKESCRQEARKLCARLI
EEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
EERVIFEREDEISALAVEGDGPASVTADES
HHHHHHCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SYMLKSIPPRHIQVFMFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGV
CCCHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCH
AVNVLRTLGVDFDTAKNEVERLIGYGPEIQVYGDPALTGRVKKSFESANEEASILEHNYV
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHCCC
GTEHLLLGILNQADGVALQVLENLHIDPKEIRKEILKELETFNLQLPPSSSITPRNTNSS
CHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCC
SSSSSKSSSLGGHSLGGDKPEKLSALKAYGYDLTEMFKEARLDPVIGRSAEVERLILILC
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RRRKNNPVLIGEAGVGKTAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQF
HCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHEEHHHHHHCCCCCCHH
EERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAIDASHILKPALARGEIQCIGATTL
HHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCHH
DEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKKYEEHHNVFITDEALVAAAKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHH
SDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSELLRLEAEIESTKQAKEQAIGTQEYE
HHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KAASLRDEEKKLREKLSNMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESE
HHHHCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCC
KLLMLENTLQKKVIGQDQAVASICRAIRRSRTGIKDPNRPMGSFLFLGPTGVGKTLLAQQ
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHH
IAVEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLFD
HHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEEH
EIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKTGEIGFGLRS
HHHHHCCHHHHHHHHHHHCCCCCHHHCCEEECCCEEEEEECCCCHHHHHHCCCCCCCHHH
HMDYGVIKEKIDAAVKKHLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNHQ
HCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
MALNIPDSVVSFLVDKGHSPEMGARPLRRVVEQYLEDPLAEMLLKESCRQEARKLCARLI
EEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
EERVIFEREDEISALAVEGDGPASVTADES
HHHHHHCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935