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The map label for this gene is clpX

Identifier: 15834703

GI number: 15834703

Start: 90884

End: 92143

Strand: Reverse

Name: clpX

Synonym: TC0078

Alternate gene names: 15834703

Gene position: 92143-90884 (Counterclockwise)

Preceding gene: 15834704

Following gene: 15834702

Centisome position: 8.59

GC content: 41.51

Gene sequence:

>1260_bases
ATGACAAAAAAAAATCTTGCGATCTGTTCTTTTTGTGGGCGATCTGAGAAGGATGTTGAGAAACTCATCGCTGGTCCATC
GGTCTACATTTGTGACTATTGTATTAAACTGTGCTCCGGGATTTTGGATAAAACTCCAACTCCCGCAGCACAAGAGGTCT
CAACATCTCAAACAGCACCTCAGACAAGTCTGAAAGTGTTAACTCCTAAAGAGATCAAACGCCACATAGACTCCTATGTT
GTTGGGCAAGAACGTGCCAAAAAAACGATTTCGGTCGCTGTCTATAATCACTATAAGCGGATCCGAGCCCTCATGCAGGA
TAAGCAGGTCAGTTATGGGAAATCCAATGTATTGTTGCTAGGCCCAACGGGATCAGGGAAGACTCTGATTGCCAAAACGT
TAGCAAAAATTTTGGATGTCCCATTTACGATCGCGGATGCAACAACCTTAACAGAAGCTGGTTATGTAGGAGAAGACGTA
GAAAATATTGTCTTACGCCTCCTGCAAGCAGCGGATTATGATGTAGCCCGCGCAGAGCGTGGAATTATTTACATCGATGA
GATCGATAAAATTGGTCGCACAACAGCTAATGTTTCTATCACTCGAGATGTTTCTGGAGAAGGAGTCCAACAGGCTCTTT
TGAAAATCATAGAAGGCACCGTTGCTAACATCCCGCCTAAAGGGGGAAGAAAGCACCCTAACCAGGAATATATTCGTGTA
AATACGGAAAATATTCTTTTCATTGTGGGAGGAGCTTTCGTTAATTTGGATAAAATTATTGCTAAAAGACTAGGCAGAAC
GACCATAGGATTTTCCGAAGAAACAGATCTTGCTGTCACTGATCGCGATCGTCTTCTCGCAAAAGTAGAAACAGAAGATT
TAATCGCATTTGGAATGATCCCAGAATTTATTGGCCGATTTAACTGTATTGTCAATTGCGAGGAGCTTACCCTAGATGAG
CTCGTTGAAATTCTTACTGAGCCAGCTAACGCTATTGTTAAGCAATATACAGAGTTATTCGCAGAAGAAAACGTAAAGTT
AATTTTCGAAAAAGAAGCTCTTTATGCTATAGCGCAAAAAGCGAAGCAAGCAAAGACAGGAGCCCGTGCTTTAGGAATGA
TTCTAGAGAATCTTCTTCGAGATCTTATGTTCGAAATACCATCTGATCCTACGGTGGAATCTATTCGCATAGAGGAAGAC
ACTATTACGCAAAACAAATCTCCTGTAATTATTCAAAGATCTCCAGAGGCTATTGCTTAA

Upstream 100 bases:

>100_bases
TATGGGAGCGGAAGAGGCTATTGCTTACGGGCTAATCGACAAGGTTGTCTCTTCAGCAAAAGAGACAAAAGATAAGAACA
TTGTGTCTTAGAGAAGTATT

Downstream 100 bases:

>100_bases
CTTTTAGGAATTGCATGACCCAGTCCACTTTGGAAACTGCGAAAAAAATTGTTCAAAAATTACGCAATGCTGGGTATCAG
GCGTATTTTGTTGGTGGGAG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTKKNLAICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKTPTPAAQEVSTSQTAPQTSLKVLTPKEIKRHIDSYV
VGQERAKKTISVAVYNHYKRIRALMQDKQVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDV
ENIVLRLLQAADYDVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIIEGTVANIPPKGGRKHPNQEYIRV
NTENILFIVGGAFVNLDKIIAKRLGRTTIGFSEETDLAVTDRDRLLAKVETEDLIAFGMIPEFIGRFNCIVNCEELTLDE
LVEILTEPANAIVKQYTELFAEENVKLIFEKEALYAIAQKAKQAKTGARALGMILENLLRDLMFEIPSDPTVESIRIEED
TITQNKSPVIIQRSPEAIA

Sequences:

>Translated_419_residues
MTKKNLAICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKTPTPAAQEVSTSQTAPQTSLKVLTPKEIKRHIDSYV
VGQERAKKTISVAVYNHYKRIRALMQDKQVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDV
ENIVLRLLQAADYDVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIIEGTVANIPPKGGRKHPNQEYIRV
NTENILFIVGGAFVNLDKIIAKRLGRTTIGFSEETDLAVTDRDRLLAKVETEDLIAFGMIPEFIGRFNCIVNCEELTLDE
LVEILTEPANAIVKQYTELFAEENVKLIFEKEALYAIAQKAKQAKTGARALGMILENLLRDLMFEIPSDPTVESIRIEED
TITQNKSPVIIQRSPEAIA
>Mature_418_residues
TKKNLAICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKTPTPAAQEVSTSQTAPQTSLKVLTPKEIKRHIDSYVV
GQERAKKTISVAVYNHYKRIRALMQDKQVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDVE
NIVLRLLQAADYDVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIIEGTVANIPPKGGRKHPNQEYIRVN
TENILFIVGGAFVNLDKIIAKRLGRTTIGFSEETDLAVTDRDRLLAKVETEDLIAFGMIPEFIGRFNCIVNCEELTLDEL
VEILTEPANAIVKQYTELFAEENVKLIFEKEALYAIAQKAKQAKTGARALGMILENLLRDLMFEIPSDPTVESIRIEEDT
ITQNKSPVIIQRSPEAIA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=325, Percent_Identity=46.7692307692308, Blast_Score=286, Evalue=4e-77,
Organism=Escherichia coli, GI1786642, Length=417, Percent_Identity=57.0743405275779, Blast_Score=460, Evalue=1e-131,
Organism=Escherichia coli, GI1790366, Length=105, Percent_Identity=40, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=321, Percent_Identity=43.9252336448598, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71982905, Length=321, Percent_Identity=43.9252336448598, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=36.5728900255754, Blast_Score=241, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=254, Percent_Identity=37.7952755905512, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=422, Percent_Identity=40.2843601895735, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24648291, Length=319, Percent_Identity=46.0815047021944, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24648289, Length=319, Percent_Identity=46.0815047021944, Blast_Score=285, Evalue=6e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_CHLMU (Q9PLM1)

Other databases:

- EMBL:   AE002160
- PIR:   C81744
- RefSeq:   NP_296462.1
- ProteinModelPortal:   Q9PLM1
- GeneID:   1245607
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0078
- TIGR:   TC_0078
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   CMUR243161:TC_0078-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46190; Mature: 46059

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKNLAICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKTPTPAAQEVSTSQTAP
CCCCCCCHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCC
QTSLKVLTPKEIKRHIDSYVVGQERAKKTISVAVYNHYKRIRALMQDKQVSYGKSNVLLL
CCCEEEECHHHHHHHHHHHHHCHHHHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDVENIVLRLLQAADYDVARAER
CCCCCCCHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHCC
GIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIIEGTVANIPPKGGRKHPNQEYIRV
CEEEEECHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEE
NTENILFIVGGAFVNLDKIIAKRLGRTTIGFSEETDLAVTDRDRLLAKVETEDLIAFGMI
ECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHCCHHHHHHHHHH
PEFIGRFNCIVNCEELTLDELVEILTEPANAIVKQYTELFAEENVKLIFEKEALYAIAQK
HHHHHHHHEEEEHHHCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
AKQAKTGARALGMILENLLRDLMFEIPSDPTVESIRIEEDTITQNKSPVIIQRSPEAIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TKKNLAICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKTPTPAAQEVSTSQTAP
CCCCCCHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCC
QTSLKVLTPKEIKRHIDSYVVGQERAKKTISVAVYNHYKRIRALMQDKQVSYGKSNVLLL
CCCEEEECHHHHHHHHHHHHHCHHHHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDVENIVLRLLQAADYDVARAER
CCCCCCCHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHCC
GIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIIEGTVANIPPKGGRKHPNQEYIRV
CEEEEECHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEE
NTENILFIVGGAFVNLDKIIAKRLGRTTIGFSEETDLAVTDRDRLLAKVETEDLIAFGMI
ECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHCCHHHHHHHHHH
PEFIGRFNCIVNCEELTLDELVEILTEPANAIVKQYTELFAEENVKLIFEKEALYAIAQK
HHHHHHHHEEEEHHHCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
AKQAKTGARALGMILENLLRDLMFEIPSDPTVESIRIEEDTITQNKSPVIIQRSPEAIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935