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Identifier: 16120217

GI number: 16120217

Start: 237209

End: 237661

Strand: Reverse

Name: Not Available

Synonym: VNG6306C

Alternate gene names: 16120217

Gene position: 237661-237209 (Counterclockwise)

Preceding gene: 16120218

Following gene: 16120216

Centisome position: 65.04

GC content: 67.33

Gene sequence:

>453_bases
ATGCGTTCAGCACAGTCCAAACGATCACAGTCCACAGCCACCGGGGAGCGGACGCTGCACATCGGGCGGGATCGCCCGAT
CCGGATCAGCGCCGGCCACCGACTGCAACACCACGACGGCAAGTGTAGCCGCCCACACGGCCACAACTACGAGATCAGCG
TCGAAATCACGGGGCAGCTCACGGACGAGGGGTGGGTTGTGGACAAGGGCACAGTCACGGCGGTGGTGTCCGACTGGGAC
CACCGGTTCCTGCTTGAGGACGGCGACCCGCTCGTTGACGCGTTCCGGGAGGCGGGCGACGGCGACGCGGTTGTCGTGCT
CGAACAGCCGCCGACCGCCGAGGTGATGGGCGTCGTGCTGGAGCGGAAGCTCCACGACGCGCTCCCTGAGACGGTGTCAG
CGGTCTCCGTCACGGTCGCGGAAACGCCGGCGCTTACTGCTGGCCCGAACTGA

Upstream 100 bases:

>100_bases
CGGCCGCCCGTGACGTGTCCCGGATCGTGGGTCGGCGACGGCAGAGCATCGTGGATATGACTTCGATATTCTTTACCGCA
TACTCGAAGAATAGGGAGAC

Downstream 100 bases:

>100_bases
TGCCGGTCAGCGAAACCACGGACCGGCAGGCGAGCAACGGTGGTGACGGGCCGGCGCTTCCGATCAACGAGCTGTTTTAC
TCCCTGCAGGGCGAGGGGAA

Product: hypothetical protein

Products: 6-pyruvoyl-5,6,7,8-tetrahydropterin; triphosphate

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRSAQSKRSQSTATGERTLHIGRDRPIRISAGHRLQHHDGKCSRPHGHNYEISVEITGQLTDEGWVVDKGTVTAVVSDWD
HRFLLEDGDPLVDAFREAGDGDAVVVLEQPPTAEVMGVVLERKLHDALPETVSAVSVTVAETPALTAGPN

Sequences:

>Translated_150_residues
MRSAQSKRSQSTATGERTLHIGRDRPIRISAGHRLQHHDGKCSRPHGHNYEISVEITGQLTDEGWVVDKGTVTAVVSDWD
HRFLLEDGDPLVDAFREAGDGDAVVVLEQPPTAEVMGVVLERKLHDALPETVSAVSVTVAETPALTAGPN
>Mature_150_residues
MRSAQSKRSQSTATGERTLHIGRDRPIRISAGHRLQHHDGKCSRPHGHNYEISVEITGQLTDEGWVVDKGTVTAVVSDWD
HRFLLEDGDPLVDAFREAGDGDAVVVLEQPPTAEVMGVVLERKLHDALPETVSAVSVTVAETPALTAGPN

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: 4.2.3.12

Molecular weight: Translated: 16234; Mature: 16234

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAQSKRSQSTATGERTLHIGRDRPIRISAGHRLQHHDGKCSRPHGHNYEISVEITGQL
CCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCEEECCCCCCCCCCCCCEEEEEEEEEEE
TDEGWVVDKGTVTAVVSDWDHRFLLEDGDPLVDAFREAGDGDAVVVLEQPPTAEVMGVVL
CCCCEEEECCEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
ERKLHDALPETVSAVSVTVAETPALTAGPN
HHHHHHHHHHHHHHEEEEEECCCEECCCCC
>Mature Secondary Structure
MRSAQSKRSQSTATGERTLHIGRDRPIRISAGHRLQHHDGKCSRPHGHNYEISVEITGQL
CCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCEEECCCCCCCCCCCCCEEEEEEEEEEE
TDEGWVVDKGTVTAVVSDWDHRFLLEDGDPLVDAFREAGDGDAVVVLEQPPTAEVMGVVL
CCCCEEEECCEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
ERKLHDALPETVSAVSVTVAETPALTAGPN
HHHHHHHHHHHHHHEEEEEECCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin

Specific reaction: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA