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The map label for this gene is sdhB

Identifier: 15836323

GI number: 15836323

Start: 888651

End: 889427

Strand: Direct

Name: sdhB

Synonym: CPj0790

Alternate gene names: 15836323

Gene position: 888651-889427 (Clockwise)

Preceding gene: 15836322

Following gene: 15836327

Centisome position: 72.45

GC content: 42.86

Gene sequence:

>777_bases
ATGATGGAGAATCTAGAGACTTTTATTTTAAAAATTTACAGAGGCGTTCCAGGGAAGCAATACTGGGAAAGCTTTGAACT
TCCTTTACATCCTGGGGAAAATGTTATCAGCGCTCTTATGGAAATCGAAAAGCGACCGGTAAATATCTTAGGGGAAAAGG
TCAATCCTGTAGTTTGGGAGCAGGGTTGCTTAGAAGAGGTCTGCGGATCCTGTTCTATTCTTGTGAATGGAGTTCCTCGT
CAGGCATGTACTGCTCTGATCCAAGAATATATCGATGCAACGCAATCCCGAGAGATTGTCCTTGCTCCTCTTACTAAGTT
CCCGTTAATCCGAGATTTAATTGTAGATAGATCGATTATGTTTGATAATCTCGAAAGGATTCAGGGTTGGGTTGCTGCGG
ATATTGAAGGAGAGACGTTTGGTCCTCAAGTCACTCAGGAACAGCAAGAGCTTCTCTATGCATTGTCGCAGTGTATGACG
TGTGGCTGCTGTACAGAAGCATGTCCCCAAATTGATAATAAAAGCGATTTCATAGGTCCTGCAGCAATTTCCCAAGCGCG
TTATTTTAATACGTATCCTGGAGATAAGCAGTCTAAGAAAAGATGGCGGGCTCTTATGGGTAAAGGAGGGATTGAGGGTT
GTGGTCAAGCGCATAACTGTGTCCGTGTCTGCCCTAAGAAACTTCCCCTTACGGAGAGCATCTCGGCCGTGGGACGTGAA
ATTTCAAAGTTCTCTTTAAGAAGTTTATTTTCAGCTCTTTTTAAAAAGAAAAAATAA

Upstream 100 bases:

>100_bases
GTAGCCCCGACTCTCCGGGATTACACAAAATCTTCAACAGGAAAAATAGAACTCACGAATATTCCTGATAATATCCGTCT
ACCCATATAGAAAAAGAGAG

Downstream 100 bases:

>100_bases
TCTAGAAAAATTCTTTAGGGAGGCGGCTGCGGTAGCCTGGAGGCGGTGGCATGCCATAATCTATAGGATTTGCATAGAGG
GTCCAGGGTCTTGACGTTGC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MMENLETFILKIYRGVPGKQYWESFELPLHPGENVISALMEIEKRPVNILGEKVNPVVWEQGCLEEVCGSCSILVNGVPR
QACTALIQEYIDATQSREIVLAPLTKFPLIRDLIVDRSIMFDNLERIQGWVAADIEGETFGPQVTQEQQELLYALSQCMT
CGCCTEACPQIDNKSDFIGPAAISQARYFNTYPGDKQSKKRWRALMGKGGIEGCGQAHNCVRVCPKKLPLTESISAVGRE
ISKFSLRSLFSALFKKKK

Sequences:

>Translated_258_residues
MMENLETFILKIYRGVPGKQYWESFELPLHPGENVISALMEIEKRPVNILGEKVNPVVWEQGCLEEVCGSCSILVNGVPR
QACTALIQEYIDATQSREIVLAPLTKFPLIRDLIVDRSIMFDNLERIQGWVAADIEGETFGPQVTQEQQELLYALSQCMT
CGCCTEACPQIDNKSDFIGPAAISQARYFNTYPGDKQSKKRWRALMGKGGIEGCGQAHNCVRVCPKKLPLTESISAVGRE
ISKFSLRSLFSALFKKKK
>Mature_258_residues
MMENLETFILKIYRGVPGKQYWESFELPLHPGENVISALMEIEKRPVNILGEKVNPVVWEQGCLEEVCGSCSILVNGVPR
QACTALIQEYIDATQSREIVLAPLTKFPLIRDLIVDRSIMFDNLERIQGWVAADIEGETFGPQVTQEQQELLYALSQCMT
CGCCTEACPQIDNKSDFIGPAAISQARYFNTYPGDKQSKKRWRALMGKGGIEGCGQAHNCVRVCPKKLPLTESISAVGRE
ISKFSLRSLFSALFKKKK

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=241, Percent_Identity=26.9709543568465, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1790596, Length=243, Percent_Identity=29.2181069958848, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786943, Length=190, Percent_Identity=31.5789473684211, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17533915, Length=250, Percent_Identity=24.8, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322987, Length=249, Percent_Identity=26.9076305220884, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24643156, Length=260, Percent_Identity=29.2307692307692, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17137106, Length=246, Percent_Identity=28.4552845528455, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28870; Mature: 28870

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMENLETFILKIYRGVPGKQYWESFELPLHPGENVISALMEIEKRPVNILGEKVNPVVWE
CCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHH
QGCLEEVCGSCSILVNGVPRQACTALIQEYIDATQSREIVLAPLTKFPLIRDLIVDRSIM
HHHHHHHCCCCEEHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
FDNLERIQGWVAADIEGETFGPQVTQEQQELLYALSQCMTCGCCTEACPQIDNKSDFIGP
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AAISQARYFNTYPGDKQSKKRWRALMGKGGIEGCGQAHNCVRVCPKKLPLTESISAVGRE
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
ISKFSLRSLFSALFKKKK
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMENLETFILKIYRGVPGKQYWESFELPLHPGENVISALMEIEKRPVNILGEKVNPVVWE
CCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHH
QGCLEEVCGSCSILVNGVPRQACTALIQEYIDATQSREIVLAPLTKFPLIRDLIVDRSIM
HHHHHHHCCCCEEHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
FDNLERIQGWVAADIEGETFGPQVTQEQQELLYALSQCMTCGCCTEACPQIDNKSDFIGP
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AAISQARYFNTYPGDKQSKKRWRALMGKGGIEGCGQAHNCVRVCPKKLPLTESISAVGRE
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
ISKFSLRSLFSALFKKKK
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]