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The map label for this gene is ahpC

Identifier: 15836311

GI number: 15836311

Start: 876826

End: 877416

Strand: Direct

Name: ahpC

Synonym: CPj0778

Alternate gene names: 15836311

Gene position: 876826-877416 (Clockwise)

Preceding gene: 15836310

Following gene: 15836319

Centisome position: 71.49

GC content: 40.78

Gene sequence:

>591_bases
ATGACACTCTCCCTAGTTGGAAAGGAAGCCCCTGATTTTGTTGCGCAAGCTGTTGTTAATGGCGAAACGTGTACCGTATC
TTTAAAAGATTATTTAGGAAAGTATGTTGTGCTTTTCTTCTATCCTAAAGATTTTACTTACGTGTGTCCTACGGAATTGC
ACGCATTTCAAGATGCTTTAGGAGAATTCCACACCCGAGGAGCTGAAGTCATAGGCTGTTCCGTGGATGACATTGCCACC
CATCAACAGTGGTTAGCTACTAAGAAAAAGCAAGGTGGTATCGAAGGTATTACCTATCCTCTTCTCTCAGACGAAGATAA
AGTCATTTCAAGAAGTTATCATGTGTTAAAACCCGAAGAAGAATTATCTTTCAGAGGAGTTTTCCTGATTGATAAAGGTG
GAATCATCCGTCATCTTGTAGTGAATGATCTTCCTCTAGGCCGTTCTATAGAAGAAGAACTTAGAACCCTAGATGCTTTA
ATCTTCTTTGAAACTAATGGCTTAGTCTGTCCTGCAAATTGGCATGAAGGAGAGCGAGCGATGGCTCCAAATGAAGAAGG
ACTGCAAAATTATTTCGGGACTATAGACTAG

Upstream 100 bases:

>100_bases
AGTAGCTCAGTCGGATAGAGTACCTGGCTACGAACCAGGTGGTCAGAGGTTCGAGTCCTCTCTGGTGCGGAACAATAAAA
GAGTTGAAGAAGAGGTTTTT

Downstream 100 bases:

>100_bases
AAAGGCTGATTGAAAGTCAGCAAGTCATAAAGATCGTGATCAAAGAACAATAAAAGGCTATTGTGTTTTTGGCATAAAGA
CCGAGAAGCTTCAATGATGT

Product: thio-specific antioxidant (TSA) peroxidase

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTLSLVGKEAPDFVAQAVVNGETCTVSLKDYLGKYVVLFFYPKDFTYVCPTELHAFQDALGEFHTRGAEVIGCSVDDIAT
HQQWLATKKKQGGIEGITYPLLSDEDKVISRSYHVLKPEEELSFRGVFLIDKGGIIRHLVVNDLPLGRSIEEELRTLDAL
IFFETNGLVCPANWHEGERAMAPNEEGLQNYFGTID

Sequences:

>Translated_196_residues
MTLSLVGKEAPDFVAQAVVNGETCTVSLKDYLGKYVVLFFYPKDFTYVCPTELHAFQDALGEFHTRGAEVIGCSVDDIAT
HQQWLATKKKQGGIEGITYPLLSDEDKVISRSYHVLKPEEELSFRGVFLIDKGGIIRHLVVNDLPLGRSIEEELRTLDAL
IFFETNGLVCPANWHEGERAMAPNEEGLQNYFGTID
>Mature_195_residues
TLSLVGKEAPDFVAQAVVNGETCTVSLKDYLGKYVVLFFYPKDFTYVCPTELHAFQDALGEFHTRGAEVIGCSVDDIATH
QQWLATKKKQGGIEGITYPLLSDEDKVISRSYHVLKPEEELSFRGVFLIDKGGIIRHLVVNDLPLGRSIEEELRTLDALI
FFETNGLVCPANWHEGERAMAPNEEGLQNYFGTID

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=187, Percent_Identity=48.1283422459893, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI5802974, Length=191, Percent_Identity=48.6910994764398, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI4505591, Length=188, Percent_Identity=48.4042553191489, Blast_Score=188, Evalue=2e-48,
Organism=Homo sapiens, GI32455266, Length=188, Percent_Identity=48.4042553191489, Blast_Score=188, Evalue=2e-48,
Organism=Homo sapiens, GI32455264, Length=188, Percent_Identity=48.4042553191489, Blast_Score=188, Evalue=2e-48,
Organism=Homo sapiens, GI32483377, Length=189, Percent_Identity=48.6772486772487, Blast_Score=187, Evalue=3e-48,
Organism=Homo sapiens, GI5453549, Length=196, Percent_Identity=43.3673469387755, Blast_Score=177, Evalue=6e-45,
Organism=Homo sapiens, GI33188454, Length=107, Percent_Identity=48.5981308411215, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4758638, Length=197, Percent_Identity=25.8883248730964, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786822, Length=183, Percent_Identity=34.9726775956284, Blast_Score=120, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI193204376, Length=192, Percent_Identity=46.875, Blast_Score=190, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI32565831, Length=192, Percent_Identity=46.875, Blast_Score=189, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17554494, Length=186, Percent_Identity=46.2365591397849, Blast_Score=184, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25153706, Length=188, Percent_Identity=25, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=43.6842105263158, Blast_Score=167, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6320661, Length=187, Percent_Identity=41.7112299465241, Blast_Score=159, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6319407, Length=187, Percent_Identity=31.0160427807487, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17157991, Length=187, Percent_Identity=47.5935828877005, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24641739, Length=187, Percent_Identity=47.5935828877005, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24656348, Length=192, Percent_Identity=46.3541666666667, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17864676, Length=192, Percent_Identity=46.3541666666667, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17738015, Length=190, Percent_Identity=47.8947368421053, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21357347, Length=192, Percent_Identity=42.7083333333333, Blast_Score=174, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24581278, Length=183, Percent_Identity=27.8688524590164, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17975518, Length=186, Percent_Identity=29.5698924731183, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652434, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24652436, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21900; Mature: 21769

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSLVGKEAPDFVAQAVVNGETCTVSLKDYLGKYVVLFFYPKDFTYVCPTELHAFQDAL
CEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHCCEEEEEEECCCCEEECCHHHHHHHHHH
GEFHTRGAEVIGCSVDDIATHQQWLATKKKQGGIEGITYPLLSDEDKVISRSYHVLKPEE
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHCCEEEECCHH
ELSFRGVFLIDKGGIIRHLVVNDLPLGRSIEEELRTLDALIFFETNGLVCPANWHEGERA
HCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHEEEEEECCCEEECCCCCCCCCC
MAPNEEGLQNYFGTID
CCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TLSLVGKEAPDFVAQAVVNGETCTVSLKDYLGKYVVLFFYPKDFTYVCPTELHAFQDAL
EEEECCCCCHHHHHHHHCCCCEEEEEHHHHHCCEEEEEEECCCCEEECCHHHHHHHHHH
GEFHTRGAEVIGCSVDDIATHQQWLATKKKQGGIEGITYPLLSDEDKVISRSYHVLKPEE
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHCCEEEECCHH
ELSFRGVFLIDKGGIIRHLVVNDLPLGRSIEEELRTLDALIFFETNGLVCPANWHEGERA
HCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHEEEEEECCCEEECCCCCCCCCC
MAPNEEGLQNYFGTID
CCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]