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The map label for this gene is dsbD

Identifier: 15836319

GI number: 15836319

Start: 882506

End: 884617

Strand: Direct

Name: dsbD

Synonym: CPj0786

Alternate gene names: 15836319

Gene position: 882506-884617 (Clockwise)

Preceding gene: 15836311

Following gene: 15836320

Centisome position: 71.95

GC content: 43.99

Gene sequence:

>2112_bases
TTGATAGCACCTTTCTTTTCTTTCCCAGCGTTATCTGGAAGTTTTTCCTCTATCCAGGCGGAAGAAATTACACAACAAGT
GAATCATCCAGGTGCAGAACTCCTTTCTGAGGGTAGCTACATCCCTGGACTACAGACATTCCGATTGGGGATCAAGATTA
CAGCTTCCAAAGGGAGCCATATCTACTGGAAGAATCCCGGAGAAATTGGAAGTCCTCTCAAAATTTCTTGGCAGTTGCCG
AAAGGTTTCGTGGTTGAAGAAGAGCATTGGCCTACCCCCAAAGTATTTGAGGAAGAGGGCACTACATTTTTTGGATATGA
AGATTCCGCTCTTATTGTCGCAGATGTCCGTGCTCCTGAAGGATACACTCCTGGTCAGGAGGTCGAATTACGAGCTCAGG
TCGAATGGCTAGCTTGTGGAGATAGTTGCTTGCCCGGGAACGTCGATCTAAAATTGACACTGCCCTACGAAGAGAAGGAG
CCTTCTCTTTATCCTGATACACACGCAGAATTTACTAAAACGCTGCATGCGCAACCTCGTGTTTTAGAAAATGATCACTC
TGTTCAAGTGGCGCAAGGAAAAGGAAATGAGATCATTTTAAATATCTCTAAGAAGATCAACGCTACGAAAGCATGGTTTG
TTTCTGAAAAAGCCGATAAGCTTTTTGCTTATGCAGAGACCTCTTATAGCGGGGGAACAGGAACTGCATGGAGATTAAAA
GTAAAAAATCTCTCCGGAGTTCAGAAGAATGAGAAGCTTCATGGGATACTGCTGTTAGCCGACCACACAGGTCGTCCCGT
AGAATCACTCACCATTCATAGTGAAGTTCTTGGTCAAACAGGATCTGCTGTAGCAGGACTGTCACAATATATCACAATTT
TGATCATGGCCTTTCTCGGCGGGGTCTTGTTGAATATTATGCCTTGTGTGCTTCCTTTAGTGACCCTGAAGGTCTACGGT
TTAATAAAATCTGCTGGAGAGCACCGCTCTTCTGTAATTGCCAATGGCTTATGGTTTACTTTAGGGGTTGTAGGATGTTT
CTGGGGATTGGCAGGTGTTGCCTTTATACTTAAGGTTTTAGGTCACAATATCGGCTGGGGCTTCCAACTCCAAGAGCCTA
TGTTTGTTGCCACATTGATCATAGTATTCTTCTTATTTGCTTTAAGTTCTCTAGGGCTTTTTGAAATGGGGACCATGTTT
GCAAACCTAGGAGGGAAGTTACAATCTTCAGAGATGAAGAGCTCTAATAATAAAGCTGTAGGGGCCTTTTTTAATGGTAT
TTTAGCTACGCTAGTCACGACTCCTTGTACAGGACCCTTCTTAGGTTCCGTATTGGGATTAGTCATGTCTTTATCTTTCC
TGCAGCAGCTCTTGATTTTTACTGCGATAGGCCTGGGGATGGCTTCACCTTACCTAGTCTTTTCTGTATTTCCAAAAATG
TTGTCCGTACTTCCTAAGCCTGGGGGATGGATGAGCACCTTCAAACAGCTAACAGGATTTATGTTGTTAGTAACGGTAAC
TTGGTTGGTATGGATTTTTGGTTCTGAAACAAGTACAACTTCTGTTGTTGTTCTCCTTGGAGGACTGTGGCTTGCAGGAT
TAGGAGCTTGGATTTTAGGACGTTGGGGAACCCCCGTCTCTCCTAAAAAACAACGTGTTTGTGCTTCTTTATTGTTCTTT
GCATTCCTAGGTGGAGCCATCTCTGTAAGTGGTTTAGCTTCTCATTACTTTGCTGAACCTCAGCAGACAGTCAGTGTGAA
CGAAGATAGTTTATGGCAGCCTTTTTCCTTAGAGAAGCTTGCCCAATTGCGAGCCCAAGGTCGTCCTGTTTTTGTGAACT
TCACGGCTAAGTGGTGCTTGACTTGTCAGATGAACAAGCCTGTTTTGTATGGTGATGCTGTGCAAAAGATGTTCGAAACT
CATGGAATTGTGACTTTAGAGGCAGATTGGACCCGTAAGGATCCAGGGATTACAGAGGAGCTTGCTCGGTTAGGTCGCGC
AAGTGTCCCTTCGTATGTCTACTATCCTGGAGATAACTCTGCACCTGTCGTACTTCCAGAAAAGATTACACAAAATCTTT
TAGAAGACGTCGTAAGTCGATTTGTAAGGTAG

Upstream 100 bases:

>100_bases
TTTATAAAATGGAATATAAAAATTAATGTATAATTAGTAACTTGATTTATAAAATCACGGTGTTATTTTGAATAAATTCA
AAACATATTTACAAACCGCA

Downstream 100 bases:

>100_bases
CTGTTAAGTGTAGAACCAACACAAGCATTCGTAGGTGGAATCATCCACGAGGTACCTTAAAAATTGTTAGGGCAGCATAT
GCTGCCCTTTTTATTTGTAA

Product: thio:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MIAPFFSFPALSGSFSSIQAEEITQQVNHPGAELLSEGSYIPGLQTFRLGIKITASKGSHIYWKNPGEIGSPLKISWQLP
KGFVVEEEHWPTPKVFEEEGTTFFGYEDSALIVADVRAPEGYTPGQEVELRAQVEWLACGDSCLPGNVDLKLTLPYEEKE
PSLYPDTHAEFTKTLHAQPRVLENDHSVQVAQGKGNEIILNISKKINATKAWFVSEKADKLFAYAETSYSGGTGTAWRLK
VKNLSGVQKNEKLHGILLLADHTGRPVESLTIHSEVLGQTGSAVAGLSQYITILIMAFLGGVLLNIMPCVLPLVTLKVYG
LIKSAGEHRSSVIANGLWFTLGVVGCFWGLAGVAFILKVLGHNIGWGFQLQEPMFVATLIIVFFLFALSSLGLFEMGTMF
ANLGGKLQSSEMKSSNNKAVGAFFNGILATLVTTPCTGPFLGSVLGLVMSLSFLQQLLIFTAIGLGMASPYLVFSVFPKM
LSVLPKPGGWMSTFKQLTGFMLLVTVTWLVWIFGSETSTTSVVVLLGGLWLAGLGAWILGRWGTPVSPKKQRVCASLLFF
AFLGGAISVSGLASHYFAEPQQTVSVNEDSLWQPFSLEKLAQLRAQGRPVFVNFTAKWCLTCQMNKPVLYGDAVQKMFET
HGIVTLEADWTRKDPGITEELARLGRASVPSYVYYPGDNSAPVVLPEKITQNLLEDVVSRFVR

Sequences:

>Translated_703_residues
MIAPFFSFPALSGSFSSIQAEEITQQVNHPGAELLSEGSYIPGLQTFRLGIKITASKGSHIYWKNPGEIGSPLKISWQLP
KGFVVEEEHWPTPKVFEEEGTTFFGYEDSALIVADVRAPEGYTPGQEVELRAQVEWLACGDSCLPGNVDLKLTLPYEEKE
PSLYPDTHAEFTKTLHAQPRVLENDHSVQVAQGKGNEIILNISKKINATKAWFVSEKADKLFAYAETSYSGGTGTAWRLK
VKNLSGVQKNEKLHGILLLADHTGRPVESLTIHSEVLGQTGSAVAGLSQYITILIMAFLGGVLLNIMPCVLPLVTLKVYG
LIKSAGEHRSSVIANGLWFTLGVVGCFWGLAGVAFILKVLGHNIGWGFQLQEPMFVATLIIVFFLFALSSLGLFEMGTMF
ANLGGKLQSSEMKSSNNKAVGAFFNGILATLVTTPCTGPFLGSVLGLVMSLSFLQQLLIFTAIGLGMASPYLVFSVFPKM
LSVLPKPGGWMSTFKQLTGFMLLVTVTWLVWIFGSETSTTSVVVLLGGLWLAGLGAWILGRWGTPVSPKKQRVCASLLFF
AFLGGAISVSGLASHYFAEPQQTVSVNEDSLWQPFSLEKLAQLRAQGRPVFVNFTAKWCLTCQMNKPVLYGDAVQKMFET
HGIVTLEADWTRKDPGITEELARLGRASVPSYVYYPGDNSAPVVLPEKITQNLLEDVVSRFVR
>Mature_703_residues
MIAPFFSFPALSGSFSSIQAEEITQQVNHPGAELLSEGSYIPGLQTFRLGIKITASKGSHIYWKNPGEIGSPLKISWQLP
KGFVVEEEHWPTPKVFEEEGTTFFGYEDSALIVADVRAPEGYTPGQEVELRAQVEWLACGDSCLPGNVDLKLTLPYEEKE
PSLYPDTHAEFTKTLHAQPRVLENDHSVQVAQGKGNEIILNISKKINATKAWFVSEKADKLFAYAETSYSGGTGTAWRLK
VKNLSGVQKNEKLHGILLLADHTGRPVESLTIHSEVLGQTGSAVAGLSQYITILIMAFLGGVLLNIMPCVLPLVTLKVYG
LIKSAGEHRSSVIANGLWFTLGVVGCFWGLAGVAFILKVLGHNIGWGFQLQEPMFVATLIIVFFLFALSSLGLFEMGTMF
ANLGGKLQSSEMKSSNNKAVGAFFNGILATLVTTPCTGPFLGSVLGLVMSLSFLQQLLIFTAIGLGMASPYLVFSVFPKM
LSVLPKPGGWMSTFKQLTGFMLLVTVTWLVWIFGSETSTTSVVVLLGGLWLAGLGAWILGRWGTPVSPKKQRVCASLLFF
AFLGGAISVSGLASHYFAEPQQTVSVNEDSLWQPFSLEKLAQLRAQGRPVFVNFTAKWCLTCQMNKPVLYGDAVQKMFET
HGIVTLEADWTRKDPGITEELARLGRASVPSYVYYPGDNSAPVVLPEKITQNLLEDVVSRFVR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=396, Percent_Identity=28.030303030303, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 76642; Mature: 76642

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPFFSFPALSGSFSSIQAEEITQQVNHPGAELLSEGSYIPGLQTFRLGIKITASKGSH
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEEEEECCCCE
IYWKNPGEIGSPLKISWQLPKGFVVEEEHWPTPKVFEEEGTTFFGYEDSALIVADVRAPE
EEECCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCC
GYTPGQEVELRAQVEWLACGDSCLPGNVDLKLTLPYEEKEPSLYPDTHAEFTKTLHAQPR
CCCCCCCEEEEEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCC
VLENDHSVQVAQGKGNEIILNISKKINATKAWFVSEKADKLFAYAETSYSGGTGTAWRLK
EECCCCCEEEECCCCCEEEEEECCCCCCCHHEEECCHHHHEEEEEECCCCCCCCCEEEEE
VKNLSGVQKNEKLHGILLLADHTGRPVESLTIHSEVLGQTGSAVAGLSQYITILIMAFLG
ECCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GVLLNIMPCVLPLVTLKVYGLIKSAGEHRSSVIANGLWFTLGVVGCFWGLAGVAFILKVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHNIGWGFQLQEPMFVATLIIVFFLFALSSLGLFEMGTMFANLGGKLQSSEMKSSNNKAV
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCCCH
GAFFNGILATLVTTPCTGPFLGSVLGLVMSLSFLQQLLIFTAIGLGMASPYLVFSVFPKM
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LSVLPKPGGWMSTFKQLTGFMLLVTVTWLVWIFGSETSTTSVVVLLGGLWLAGLGAWILG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RWGTPVSPKKQRVCASLLFFAFLGGAISVSGLASHYFAEPQQTVSVNEDSLWQPFSLEKL
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHH
AQLRAQGRPVFVNFTAKWCLTCQMNKPVLYGDAVQKMFETHGIVTLEADWTRKDPGITEE
HHHHHCCCCEEEEEEEEEEEEEECCCCEEEHHHHHHHHHHCCEEEEECCCCCCCCCHHHH
LARLGRASVPSYVYYPGDNSAPVVLPEKITQNLLEDVVSRFVR
HHHCCCCCCCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAPFFSFPALSGSFSSIQAEEITQQVNHPGAELLSEGSYIPGLQTFRLGIKITASKGSH
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEEEEECCCCE
IYWKNPGEIGSPLKISWQLPKGFVVEEEHWPTPKVFEEEGTTFFGYEDSALIVADVRAPE
EEECCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCC
GYTPGQEVELRAQVEWLACGDSCLPGNVDLKLTLPYEEKEPSLYPDTHAEFTKTLHAQPR
CCCCCCCEEEEEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCC
VLENDHSVQVAQGKGNEIILNISKKINATKAWFVSEKADKLFAYAETSYSGGTGTAWRLK
EECCCCCEEEECCCCCEEEEEECCCCCCCHHEEECCHHHHEEEEEECCCCCCCCCEEEEE
VKNLSGVQKNEKLHGILLLADHTGRPVESLTIHSEVLGQTGSAVAGLSQYITILIMAFLG
ECCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GVLLNIMPCVLPLVTLKVYGLIKSAGEHRSSVIANGLWFTLGVVGCFWGLAGVAFILKVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHNIGWGFQLQEPMFVATLIIVFFLFALSSLGLFEMGTMFANLGGKLQSSEMKSSNNKAV
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCCCH
GAFFNGILATLVTTPCTGPFLGSVLGLVMSLSFLQQLLIFTAIGLGMASPYLVFSVFPKM
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LSVLPKPGGWMSTFKQLTGFMLLVTVTWLVWIFGSETSTTSVVVLLGGLWLAGLGAWILG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RWGTPVSPKKQRVCASLLFFAFLGGAISVSGLASHYFAEPQQTVSVNEDSLWQPFSLEKL
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHH
AQLRAQGRPVFVNFTAKWCLTCQMNKPVLYGDAVQKMFETHGIVTLEADWTRKDPGITEE
HHHHHCCCCEEEEEEEEEEEEEECCCCEEEHHHHHHHHHHCCEEEEECCCCCCCCCHHHH
LARLGRASVPSYVYYPGDNSAPVVLPEKITQNLLEDVVSRFVR
HHHCCCCCCCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]