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The map label for this gene is mrdB [H]

Identifier: 15595064

GI number: 15595064

Start: 756291

End: 757670

Strand: Direct

Name: mrdB [H]

Synonym: BB0719

Alternate gene names: 15595064

Gene position: 756291-757670 (Clockwise)

Preceding gene: 15595063

Following gene: 15595065

Centisome position: 83.04

GC content: 27.46

Gene sequence:

>1380_bases
TTGCAAATCAAAGTTATGAAGATATTCTTAAAGGTTATAGGCCGTGGTATATTAGGTAGATTAATGGTTTTTAGAAAAAA
TTATGATTATTTGGCTTTGATAAGCTTACTTATAGTTTCTTTTGTTGGTATATTGTTGATTTATTCTAGCGATTATAATA
TTAGTGGATCTTTAACCAAGAATGAATATATAAAACAAACCTTTTGGGTAATTATTGGATTTTTTCTAATTTTTATAGTG
GGCAAATATGATTTAAAATTTGTTTATAGCATGGTATATCCTTTATATTTTTTATTAATATTGGCTTTAATTTTTACTGC
ATTTTTTGGAATGACAGTAAATGGAGCAAGATCTTGGATTGGCATATGGAAACTTGGAGGACAGCCTTCTGAATTTGGTA
AAGTTGTTATTATTTTAACCCTTTCAAAATTTTACACTGAAAAAAAGGGTTATAATGAATTTTTTACCTTTATTACTGCA
TTTTTATTAATTTTTCCATCGGTAATTCTTATATTATTGCAACCTGATTTTGGTACAGCAATAGTATATTTAACCATTTT
TATATTTATTTCTTTTTTTGCAGGAATAGATTTGCACTATGTTTTAGCATTTGCGTTGATAGGGTTTTTTTCTTTTGTTT
TTGCAATTTTACCGGTTTGGTATGAATATAAGGTGAATATGGGTAATGTATTTTATCTTATTTTCTCAAATCCTTTTTAT
TTTAGAGTAATAATGGGAGTGCTGCTTTTAATTCTTTTGATTTCTGTTTTAGGATTTTTCATTTCTAAATATGGTTTGAG
TATTAAAATAATTTATTTTTATGTATTTTTTGCAAGTTCTATTTTATTAGTTTCAATAGTGTTTTCAAAGGTTCTTTCAA
AGTTAATGAAGACTTATCAGATTAAACGGTTTTTGGTATTCTTAGATCCGGCTATTGATGCTAAGGGTGCTGGTTGGAAT
TTAAATCAGGTTAAAATAGCAATTGGTTCTGGCGGTCTTTTGGGCAAAGGATTTTTAAAGGGACCTTATACCCACGCTAA
TTATGTGCCATCTCAAAGCACAGATTTTATTTTTTCTATTCTTGCCGAAGAGTTTGGGTTTTTGGGTGTTAGCACTATTT
TAATATTATTTTTTTTCCTTTTTTTTAAATTTTTGATAATAATGAATAAAAGTCAAGATAGATATATGGCCTTAGTAATA
TCTGGAATTTTGGGACTTTTATTTTTTCATACTTCTTTTAATGTTGGAATGTCTTTAGGAGTTCTTCCTATTACCGGGAT
TCCCTTTCCTTTTCTCTCTTATGGAGGTTCTTCTACTATTACATTTTTTTTAGCAATGTCTTTTTATTTTAATATTGAAT
CAATAGTTGCTATGGATTGA

Upstream 100 bases:

>100_bases
TCAGCTGATAATCAAATTATTGTTTTTAGTTTGGTTGAGGCAAAAAGTAATGTGGATTGGTGGCCTGCAAAATCTACAGA
TTTAATAATGCAAGGCATTT

Downstream 100 bases:

>100_bases
AAATTTATTTTCAGGTTTTTGTTTTCTTATCTCTATTTTTTTAGAAAATTTTTTTGTATATTTTAATTTAGTAATTATAA
ATATTTGAGGTGCGTATTTT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MQIKVMKIFLKVIGRGILGRLMVFRKNYDYLALISLLIVSFVGILLIYSSDYNISGSLTKNEYIKQTFWVIIGFFLIFIV
GKYDLKFVYSMVYPLYFLLILALIFTAFFGMTVNGARSWIGIWKLGGQPSEFGKVVIILTLSKFYTEKKGYNEFFTFITA
FLLIFPSVILILLQPDFGTAIVYLTIFIFISFFAGIDLHYVLAFALIGFFSFVFAILPVWYEYKVNMGNVFYLIFSNPFY
FRVIMGVLLLILLISVLGFFISKYGLSIKIIYFYVFFASSILLVSIVFSKVLSKLMKTYQIKRFLVFLDPAIDAKGAGWN
LNQVKIAIGSGGLLGKGFLKGPYTHANYVPSQSTDFIFSILAEEFGFLGVSTILILFFFLFFKFLIIMNKSQDRYMALVI
SGILGLLFFHTSFNVGMSLGVLPITGIPFPFLSYGGSSTITFFLAMSFYFNIESIVAMD

Sequences:

>Translated_459_residues
MQIKVMKIFLKVIGRGILGRLMVFRKNYDYLALISLLIVSFVGILLIYSSDYNISGSLTKNEYIKQTFWVIIGFFLIFIV
GKYDLKFVYSMVYPLYFLLILALIFTAFFGMTVNGARSWIGIWKLGGQPSEFGKVVIILTLSKFYTEKKGYNEFFTFITA
FLLIFPSVILILLQPDFGTAIVYLTIFIFISFFAGIDLHYVLAFALIGFFSFVFAILPVWYEYKVNMGNVFYLIFSNPFY
FRVIMGVLLLILLISVLGFFISKYGLSIKIIYFYVFFASSILLVSIVFSKVLSKLMKTYQIKRFLVFLDPAIDAKGAGWN
LNQVKIAIGSGGLLGKGFLKGPYTHANYVPSQSTDFIFSILAEEFGFLGVSTILILFFFLFFKFLIIMNKSQDRYMALVI
SGILGLLFFHTSFNVGMSLGVLPITGIPFPFLSYGGSSTITFFLAMSFYFNIESIVAMD
>Mature_459_residues
MQIKVMKIFLKVIGRGILGRLMVFRKNYDYLALISLLIVSFVGILLIYSSDYNISGSLTKNEYIKQTFWVIIGFFLIFIV
GKYDLKFVYSMVYPLYFLLILALIFTAFFGMTVNGARSWIGIWKLGGQPSEFGKVVIILTLSKFYTEKKGYNEFFTFITA
FLLIFPSVILILLQPDFGTAIVYLTIFIFISFFAGIDLHYVLAFALIGFFSFVFAILPVWYEYKVNMGNVFYLIFSNPFY
FRVIMGVLLLILLISVLGFFISKYGLSIKIIYFYVFFASSILLVSIVFSKVLSKLMKTYQIKRFLVFLDPAIDAKGAGWN
LNQVKIAIGSGGLLGKGFLKGPYTHANYVPSQSTDFIFSILAEEFGFLGVSTILILFFFLFFKFLIIMNKSQDRYMALVI
SGILGLLFFHTSFNVGMSLGVLPITGIPFPFLSYGGSSTITFFLAMSFYFNIESIVAMD

Specific function: This is one of the proteins responsible for the rod shape of the cell [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=160, Percent_Identity=40, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786277, Length=162, Percent_Identity=35.1851851851852, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 52179; Mature: 52179

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKVMKIFLKVIGRGILGRLMVFRKNYDYLALISLLIVSFVGILLIYSSDYNISGSLTK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
NEYIKQTFWVIIGFFLIFIVGKYDLKFVYSMVYPLYFLLILALIFTAFFGMTVNGARSWI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEE
GIWKLGGQPSEFGKVVIILTLSKFYTEKKGYNEFFTFITAFLLIFPSVILILLQPDFGTA
EEEECCCCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IVYLTIFIFISFFAGIDLHYVLAFALIGFFSFVFAILPVWYEYKVNMGNVFYLIFSNPFY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCHH
FRVIMGVLLLILLISVLGFFISKYGLSIKIIYFYVFFASSILLVSIVFSKVLSKLMKTYQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKRFLVFLDPAIDAKGAGWNLNQVKIAIGSGGLLGKGFLKGPYTHANYVPSQSTDFIFSI
HHHHHHEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAEEFGFLGVSTILILFFFLFFKFLIIMNKSQDRYMALVISGILGLLFFHTSFNVGMSLG
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEC
VLPITGIPFPFLSYGGSSTITFFLAMSFYFNIESIVAMD
CEEECCCCCHHHHCCCCHHHHHHHHHHHHHCHHHHEECC
>Mature Secondary Structure
MQIKVMKIFLKVIGRGILGRLMVFRKNYDYLALISLLIVSFVGILLIYSSDYNISGSLTK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
NEYIKQTFWVIIGFFLIFIVGKYDLKFVYSMVYPLYFLLILALIFTAFFGMTVNGARSWI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEE
GIWKLGGQPSEFGKVVIILTLSKFYTEKKGYNEFFTFITAFLLIFPSVILILLQPDFGTA
EEEECCCCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IVYLTIFIFISFFAGIDLHYVLAFALIGFFSFVFAILPVWYEYKVNMGNVFYLIFSNPFY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCHH
FRVIMGVLLLILLISVLGFFISKYGLSIKIIYFYVFFASSILLVSIVFSKVLSKLMKTYQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKRFLVFLDPAIDAKGAGWNLNQVKIAIGSGGLLGKGFLKGPYTHANYVPSQSTDFIFSI
HHHHHHEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAEEFGFLGVSTILILFFFLFFKFLIIMNKSQDRYMALVISGILGLLFFHTSFNVGMSLG
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEC
VLPITGIPFPFLSYGGSSTITFFLAMSFYFNIESIVAMD
CEEECCCCCHHHHCCCCHHHHHHHHHHHHHCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]