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The map label for this gene is tpn39b [H]

Identifier: 15594454

GI number: 15594454

Start: 105884

End: 106894

Strand: Reverse

Name: tpn39b [H]

Synonym: BB0108

Alternate gene names: 15594454

Gene position: 106894-105884 (Counterclockwise)

Preceding gene: 15594455

Following gene: 15594453

Centisome position: 11.74

GC content: 30.46

Gene sequence:

>1011_bases
ATGAAGAGTTTTTTATTTTGGGTAATATTGGGAACTGTAGGGATTAGCTCTTTTGCTCAAAATACTCCTGTTGCTATTAT
TAATTTATATAAGAATGAAATTATTACTAAAACTGGTTTTGATTCTAAGGTTGATATATTTAAAAAGACCCAAGGTAGAG
ACTTAACTGATGCTGAGAAAAAGCAAGTTCTGCAAGTTTTAATAGCAGATGTTCTTTTTAGTCAAGAGGCTTCAAAGCAA
GGAATTAAAATCTCAGATGATGAGGTTATGCAAACAATTAGAACTCAATTTGGGCTTGTGAATTTTACTGATGAACAAAT
CAAGCAAATGATAGAAAAACAAGGTACAAATTGGGGCGAGCTTTTGTCTTCAATGAAAAGATCTCTGTCTTCTCAAAAGC
TTGTTTTAAAGCAAGCTCAGCCTAAGTTTTCTGAAATTAAAACTCCTAGTGAGAAAGAAATTGTTGAGTATTATGAGGCT
AATAAAACTAAGTTTGTAAATCCCGATATTTCAAGAGTTAGTCATATCTTTTTTTCTACTAAAGATAAAAAAAGATCAGA
TGTTTTAGATCAAGCAAAAAATATTTTAAGCCAAATAAGATCAAAAAAAATTACTTTTGAAGAAGCTGTAAGAAAATATT
CAAATGACGAATCTTCTAAGGCTAAAAATGGTGATCTTGGGTTTTTATCAAGAGGTGATCAAAATGCTCAAAATCTTCTT
GGAGCCGATTTTGTGAAAGAGGTTTTTAATTTTAATAAGGGTGATATATCTTCGCCTATTGCTTCAAAGGAAGGGTTTCA
TATTGTTAAAGTTACAGAAAAATATGCTCAGAGATTTTTAGGTTTGAATGATAAAGTGTCTCCTACTGCAGATTTGATTG
TCAAAGATGCAATAAGAAATAACATGATTAATGTTCAACAACAGCAAATTGTTGTTCAAGTACAGCAAGATATGTATGGT
AAGCTTAACAAGTCTGCAAATATACAAATCTTGGATTCTAGTCTAAAATAA

Upstream 100 bases:

>100_bases
TCTAGTTTTTTGTATAGATGAAAATGTTTTATTAACTAGATTTAAATGTAAAATTTTGTTAAATTAGTGGGTAAGTGATT
CTTTAATAAGAGGTTATGTT

Downstream 100 bases:

>100_bases
AACATATTTTTATTTATATAATTTTATTATGGATTTAATGCATGAAGTTAGAGTTTTAGCTTTTCAAAAGATTTATAGCA
TTGATATTAATCAAAGCGCA

Product: basic membrane protein

Products: Isomerized Proline [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKSFLFWVILGTVGISSFAQNTPVAIINLYKNEIITKTGFDSKVDIFKKTQGRDLTDAEKKQVLQVLIADVLFSQEASKQ
GIKISDDEVMQTIRTQFGLVNFTDEQIKQMIEKQGTNWGELLSSMKRSLSSQKLVLKQAQPKFSEIKTPSEKEIVEYYEA
NKTKFVNPDISRVSHIFFSTKDKKRSDVLDQAKNILSQIRSKKITFEEAVRKYSNDESSKAKNGDLGFLSRGDQNAQNLL
GADFVKEVFNFNKGDISSPIASKEGFHIVKVTEKYAQRFLGLNDKVSPTADLIVKDAIRNNMINVQQQQIVVQVQQDMYG
KLNKSANIQILDSSLK

Sequences:

>Translated_336_residues
MKSFLFWVILGTVGISSFAQNTPVAIINLYKNEIITKTGFDSKVDIFKKTQGRDLTDAEKKQVLQVLIADVLFSQEASKQ
GIKISDDEVMQTIRTQFGLVNFTDEQIKQMIEKQGTNWGELLSSMKRSLSSQKLVLKQAQPKFSEIKTPSEKEIVEYYEA
NKTKFVNPDISRVSHIFFSTKDKKRSDVLDQAKNILSQIRSKKITFEEAVRKYSNDESSKAKNGDLGFLSRGDQNAQNLL
GADFVKEVFNFNKGDISSPIASKEGFHIVKVTEKYAQRFLGLNDKVSPTADLIVKDAIRNNMINVQQQQIVVQVQQDMYG
KLNKSANIQILDSSLK
>Mature_336_residues
MKSFLFWVILGTVGISSFAQNTPVAIINLYKNEIITKTGFDSKVDIFKKTQGRDLTDAEKKQVLQVLIADVLFSQEASKQ
GIKISDDEVMQTIRTQFGLVNFTDEQIKQMIEKQGTNWGELLSSMKRSLSSQKLVLKQAQPKFSEIKTPSEKEIVEYYEA
NKTKFVNPDISRVSHIFFSTKDKKRSDVLDQAKNILSQIRSKKITFEEAVRKYSNDESSKAKNGDLGFLSRGDQNAQNLL
GADFVKEVFNFNKGDISSPIASKEGFHIVKVTEKYAQRFLGLNDKVSPTADLIVKDAIRNNMINVQQQQIVVQVQQDMYG
KLNKSANIQILDSSLK

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008880 [H]

Pfam domain/function: NA

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 37996; Mature: 37996

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFLFWVILGTVGISSFAQNTPVAIINLYKNEIITKTGFDSKVDIFKKTQGRDLTDAEK
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHH
KQVLQVLIADVLFSQEASKQGIKISDDEVMQTIRTQFGLVNFTDEQIKQMIEKQGTNWGE
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHH
LLSSMKRSLSSQKLVLKQAQPKFSEIKTPSEKEIVEYYEANKTKFVNPDISRVSHIFFST
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHCC
KDKKRSDVLDQAKNILSQIRSKKITFEEAVRKYSNDESSKAKNGDLGFLSRGDQNAQNLL
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
GADFVKEVFNFNKGDISSPIASKEGFHIVKVTEKYAQRFLGLNDKVSPTADLIVKDAIRN
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
NMINVQQQQIVVQVQQDMYGKLNKSANIQILDSSLK
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
>Mature Secondary Structure
MKSFLFWVILGTVGISSFAQNTPVAIINLYKNEIITKTGFDSKVDIFKKTQGRDLTDAEK
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHH
KQVLQVLIADVLFSQEASKQGIKISDDEVMQTIRTQFGLVNFTDEQIKQMIEKQGTNWGE
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHH
LLSSMKRSLSSQKLVLKQAQPKFSEIKTPSEKEIVEYYEANKTKFVNPDISRVSHIFFST
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHCC
KDKKRSDVLDQAKNILSQIRSKKITFEEAVRKYSNDESSKAKNGDLGFLSRGDQNAQNLL
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
GADFVKEVFNFNKGDISSPIASKEGFHIVKVTEKYAQRFLGLNDKVSPTADLIVKDAIRN
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
NMINVQQQQIVVQVQQDMYGKLNKSANIQILDSSLK
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proline Imidic Peptide Bonds In Oligopeptides [C]

Specific reaction: Cis-Trans Isomerization Of Proline Imidic Peptide Bonds In Oligopeptides. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3552988; 9665876 [H]