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The map label for this gene is yrpG

Identifier: 255767617

GI number: 255767617

Start: 2742909

End: 2743889

Strand: Direct

Name: yrpG

Synonym: BSU26850

Alternate gene names: 255767617

Gene position: 2742909-2743889 (Clockwise)

Preceding gene: 16079735

Following gene: 255767618

Centisome position: 65.07

GC content: 45.77

Gene sequence:

>981_bases
GTGGAGTATACCTATTTAGGGAGAACAGGATTGCGGGTGAGCCGTTTATGTTTAGGCACGATGAATTTTGGAGTTGATAC
AGACGAAAAGACTGCGTTCCGTATCATGGATGAAGCACTTGATAACGGCATTCAATTTTTTGATACTGCCAATATTTACG
GCTGGGGCAAAAACGCAGGATTGACAGAGAGCATCATTGGAAAATGGTTTGCACAAGGAGGACAGCGCCGCGAGAAAGTT
GTTCTGGCGACAAAAGTATATGAACCGATTTCTGATCCGAATGACGGACCAAATGATATGAGGGGCTTGTCTCTATACAA
AATCAGACGTCATCTGGAAGGATCACTGAAGCGGCTTCAGACAGATCATATCGAATTGTACCAAATGCATCATATCGATA
GGCGGACACCGTGGGATGAGATATGGGAAGCTTTTGAGACTCAGGTTCGCTCCGGCAAAGTAGACTATATTGGATCCAGT
AATTTTGCAGGCTGGCATTTAGTTAAAGCGCAAGCTGAAGCTGAAAAACGGCGATTCATGGGACTCGTCACTGAACAGCA
TAAGTATAGTTTATTAGAACGAACAGCTGAAATGGAAGTGCTGCCGGCTGCACGGGATCTTGGTTTAGGAGTAGTGGCGT
GGAGTCCCCTTGCAGGAGGGCTTCTTGGCGGGAAGGCATTGAAAAGCAATGCCGGAACTCGTACAGCAAAAAGAGCAGAT
TTAATTGAAAAACATCGTTTGCAACTCGAGAAATTTTCAGATTTATGCAAAGAACTAGGAGAAAAAGAAGCAAATGTGGC
TTTGGCATGGGTGCTGGCAAATCCAGTTTTAACTGCGCCGATCATCGGACCACGAACGGTTGAGCAGCTGCGTGATACGA
TAAAAGCCGTTGAAATCAGTCTGGATAAGGAGATTCTCCGCATGTTAAATGATATCTTTCCCGGACCTGGAGGAGAGACA
CCTGAGGCATACGCCTGGTGA

Upstream 100 bases:

>100_bases
ACATTTGCTTCGTCTTTTTAATCGTAACAAAGAGCAAACAATTGTTGAATCAATTGTATTGCAGCTGTTGCCAAAAATAA
TGATAAAGGAGAGGTTTGTT

Downstream 100 bases:

>100_bases
TACATTCATTACTCAATACTGACATTTTTCTTAAATATTTATACTGAACTATCATATTAAGAAAGACAAGAGCATGTTTG
TCTCTTGTCTTTTCCACATC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEYTYLGRTGLRVSRLCLGTMNFGVDTDEKTAFRIMDEALDNGIQFFDTANIYGWGKNAGLTESIIGKWFAQGGQRREKV
VLATKVYEPISDPNDGPNDMRGLSLYKIRRHLEGSLKRLQTDHIELYQMHHIDRRTPWDEIWEAFETQVRSGKVDYIGSS
NFAGWHLVKAQAEAEKRRFMGLVTEQHKYSLLERTAEMEVLPAARDLGLGVVAWSPLAGGLLGGKALKSNAGTRTAKRAD
LIEKHRLQLEKFSDLCKELGEKEANVALAWVLANPVLTAPIIGPRTVEQLRDTIKAVEISLDKEILRMLNDIFPGPGGET
PEAYAW

Sequences:

>Translated_326_residues
MEYTYLGRTGLRVSRLCLGTMNFGVDTDEKTAFRIMDEALDNGIQFFDTANIYGWGKNAGLTESIIGKWFAQGGQRREKV
VLATKVYEPISDPNDGPNDMRGLSLYKIRRHLEGSLKRLQTDHIELYQMHHIDRRTPWDEIWEAFETQVRSGKVDYIGSS
NFAGWHLVKAQAEAEKRRFMGLVTEQHKYSLLERTAEMEVLPAARDLGLGVVAWSPLAGGLLGGKALKSNAGTRTAKRAD
LIEKHRLQLEKFSDLCKELGEKEANVALAWVLANPVLTAPIIGPRTVEQLRDTIKAVEISLDKEILRMLNDIFPGPGGET
PEAYAW
>Mature_326_residues
MEYTYLGRTGLRVSRLCLGTMNFGVDTDEKTAFRIMDEALDNGIQFFDTANIYGWGKNAGLTESIIGKWFAQGGQRREKV
VLATKVYEPISDPNDGPNDMRGLSLYKIRRHLEGSLKRLQTDHIELYQMHHIDRRTPWDEIWEAFETQVRSGKVDYIGSS
NFAGWHLVKAQAEAEKRRFMGLVTEQHKYSLLERTAEMEVLPAARDLGLGVVAWSPLAGGLLGGKALKSNAGTRTAKRAD
LIEKHRLQLEKFSDLCKELGEKEANVALAWVLANPVLTAPIIGPRTVEQLRDTIKAVEISLDKEILRMLNDIFPGPGGET
PEAYAW

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family

Homologues:

Organism=Homo sapiens, GI27436964, Length=328, Percent_Identity=32.0121951219512, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI27436962, Length=328, Percent_Identity=32.0121951219512, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI27436966, Length=328, Percent_Identity=31.7073170731707, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27436969, Length=328, Percent_Identity=29.8780487804878, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4504825, Length=326, Percent_Identity=29.7546012269939, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI27436971, Length=312, Percent_Identity=30.1282051282051, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI223718702, Length=305, Percent_Identity=28.5245901639344, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI41327764, Length=208, Percent_Identity=32.2115384615385, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI41152114, Length=208, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=8e-17,
Organism=Escherichia coli, GI87081735, Length=332, Percent_Identity=36.144578313253, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=30.835734870317, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789375, Length=310, Percent_Identity=29.0322580645161, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788070, Length=322, Percent_Identity=31.055900621118, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788081, Length=310, Percent_Identity=26.7741935483871, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994888, Length=300, Percent_Identity=25, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=29.940119760479, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323998, Length=324, Percent_Identity=27.4691358024691, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=307, Percent_Identity=26.0586319218241, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=328, Percent_Identity=26.219512195122, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=26.6932270916335, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640980, Length=330, Percent_Identity=24.5454545454545, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45549126, Length=330, Percent_Identity=24.5454545454545, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646155, Length=325, Percent_Identity=29.8461538461538, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646159, Length=243, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YRPG_BACSU (O05408)

Other databases:

- EMBL:   U93875
- EMBL:   AL009126
- PIR:   F69978
- RefSeq:   NP_390562.2
- HSSP:   Q9KE47
- ProteinModelPortal:   O05408
- SMR:   O05408
- EnsemblBacteria:   EBBACT00000000208
- GeneID:   937611
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU26850
- NMPDR:   fig|224308.1.peg.2687
- GenoList:   BSU26850
- GeneTree:   EBGT00070000031909
- HOGENOM:   HBG605727
- ProtClustDB:   CLSK881316
- BioCyc:   BSUB:BSU26850-MONOMER
- InterPro:   IPR023210
- Gene3D:   G3DSA:3.20.20.100

Pfam domain/function: PF00248 Aldo_ket_red; SSF51430 Aldo/ket_red

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36630; Mature: 36630

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: ACT_SITE 53-53

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYTYLGRTGLRVSRLCLGTMNFGVDTDEKTAFRIMDEALDNGIQFFDTANIYGWGKNAG
CCEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCEEECCCCCC
LTESIIGKWFAQGGQRREKVVLATKVYEPISDPNDGPNDMRGLSLYKIRRHLEGSLKRLQ
CHHHHHHHHHHCCCCCHHHEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TDHIELYQMHHIDRRTPWDEIWEAFETQVRSGKVDYIGSSNFAGWHLVKAQAEAEKRRFM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEHHHHHHHHHHH
GLVTEQHKYSLLERTAEMEVLPAARDLGLGVVAWSPLAGGLLGGKALKSNAGTRTAKRAD
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCHHCCHHCCHHHHCCCCCCHHHHHH
LIEKHRLQLEKFSDLCKELGEKEANVALAWVLANPVLTAPIIGPRTVEQLRDTIKAVEIS
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
LDKEILRMLNDIFPGPGGETPEAYAW
HHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MEYTYLGRTGLRVSRLCLGTMNFGVDTDEKTAFRIMDEALDNGIQFFDTANIYGWGKNAG
CCEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCEEECCCCCC
LTESIIGKWFAQGGQRREKVVLATKVYEPISDPNDGPNDMRGLSLYKIRRHLEGSLKRLQ
CHHHHHHHHHHCCCCCHHHEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TDHIELYQMHHIDRRTPWDEIWEAFETQVRSGKVDYIGSSNFAGWHLVKAQAEAEKRRFM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEHHHHHHHHHHH
GLVTEQHKYSLLERTAEMEVLPAARDLGLGVVAWSPLAGGLLGGKALKSNAGTRTAKRAD
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCHHCCHHCCHHHHCCCCCCHHHHHH
LIEKHRLQLEKFSDLCKELGEKEANVALAWVLANPVLTAPIIGPRTVEQLRDTIKAVEIS
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
LDKEILRMLNDIFPGPGGETPEAYAW
HHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377