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The map label for this gene is xylR

Identifier: 255767416

GI number: 255767416

Start: 1890512

End: 1891564

Strand: Reverse

Name: xylR

Synonym: BSU17590

Alternate gene names: 255767416

Gene position: 1891564-1890512 (Counterclockwise)

Preceding gene: 16078825

Following gene: 255767407

Centisome position: 44.87

GC content: 36.28

Gene sequence:

>1053_bases
ATGACTGGATTAAATAAATCAACTGTCTCATCACAGGTAAACACGTTAATGAAAGAAAGTATGGTATTTGAAATAGGTCA
AGGACAATCAAGTGGCGGAAGAAGACCTGTCATGCTTGTTTTTAATAAAAAGGCAGGATACTCCGTTGGAATAGATGTTG
GTGTGGATTATATTAATGGCATTTTAACAGACCTTGAAGGAACAATCGTTCTTGATCAATACCGCCATTTGGAATCCAAT
TCTCCAGAAATAACGAAAGACATTTTGATTGATATGATTCATCACTTTATTACGCAAATGCCCCAATCTCCGTACGGGCT
TATTGGTATAGGTATTTGCGTGCCTGGACTCATTGATAAAGATCAAAAAATTGTTTTCACTCCGAACTCCAACTGGAGAG
ATATTGACTTAAAATCTTCGATACAAGAGAAGTACAATGTGCCTGTTTTTATTGAAAATGAGGCAAATGCTGGCGCATAT
GGAGAAAAAGTATTTGGAGCTGCAAAAAATCACGATAACATTATTTACGTAAGTATCAGCACAGGAATAGGGATCGGTGT
TATTATCAACAATCATTTATATAGAGGAGTAAGCGGCTTCTCTGGAGAAATGGGACATATGACAATAGACTTTAATGGTC
CTAAATGCAGTTGCGGAAACCGAGGATGCTGGGAATTGTATGCTTCAGAGAAGGCTTTATTAAAATCTCTTCAGACCAAA
GAGAAAAAACTGTCCTATCAAGATATCATAAACCTCGCCCATCTGAATGATATCGGAACCTTAAATGCATTACAAAATTT
TGGATTCTATTTAGGAATAGGCCTTACCAATATTCTAAATACTTTCAACCCACAAGCCGTAATTTTAAGAAATAGCATAA
TTGAATCGCATCCTATGGTTTTAAATTCAATGAGAAGTGAAGTATCATCAAGGGTTTATTCCCAATTAGGCAATAGCTAT
GAATTATTGCCATCTTCCTTAGGACAGAATGCACCGGCATTAGGAATGTCCTCCATTGTGATTGATCATTTTCTGGACAT
GATTACAATGTAA

Upstream 100 bases:

>100_bases
GGATATCGCTGATCAAACCTTTGTCAAAAAAGTAAATCAAAAGTTATTATTAAAAGAAATCCTTAAAAATTCACCTATTT
CAAGAGCAAAATTATCTGAA

Downstream 100 bases:

>100_bases
TTTTTTATGGAATGGACAGCTCATCTTTAAAGATGAGTTTTTTTATTCTAGGAGTATTTCTGAAGCAATAGTGACATGGC
ACCTTCTCATATGAAAAAGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTGLNKSTVSSQVNTLMKESMVFEIGQGQSSGGRRPVMLVFNKKAGYSVGIDVGVDYINGILTDLEGTIVLDQYRHLESN
SPEITKDILIDMIHHFITQMPQSPYGLIGIGICVPGLIDKDQKIVFTPNSNWRDIDLKSSIQEKYNVPVFIENEANAGAY
GEKVFGAAKNHDNIIYVSISTGIGIGVIINNHLYRGVSGFSGEMGHMTIDFNGPKCSCGNRGCWELYASEKALLKSLQTK
EKKLSYQDIINLAHLNDIGTLNALQNFGFYLGIGLTNILNTFNPQAVILRNSIIESHPMVLNSMRSEVSSRVYSQLGNSY
ELLPSSLGQNAPALGMSSIVIDHFLDMITM

Sequences:

>Translated_350_residues
MTGLNKSTVSSQVNTLMKESMVFEIGQGQSSGGRRPVMLVFNKKAGYSVGIDVGVDYINGILTDLEGTIVLDQYRHLESN
SPEITKDILIDMIHHFITQMPQSPYGLIGIGICVPGLIDKDQKIVFTPNSNWRDIDLKSSIQEKYNVPVFIENEANAGAY
GEKVFGAAKNHDNIIYVSISTGIGIGVIINNHLYRGVSGFSGEMGHMTIDFNGPKCSCGNRGCWELYASEKALLKSLQTK
EKKLSYQDIINLAHLNDIGTLNALQNFGFYLGIGLTNILNTFNPQAVILRNSIIESHPMVLNSMRSEVSSRVYSQLGNSY
ELLPSSLGQNAPALGMSSIVIDHFLDMITM
>Mature_349_residues
TGLNKSTVSSQVNTLMKESMVFEIGQGQSSGGRRPVMLVFNKKAGYSVGIDVGVDYINGILTDLEGTIVLDQYRHLESNS
PEITKDILIDMIHHFITQMPQSPYGLIGIGICVPGLIDKDQKIVFTPNSNWRDIDLKSSIQEKYNVPVFIENEANAGAYG
EKVFGAAKNHDNIIYVSISTGIGIGVIINNHLYRGVSGFSGEMGHMTIDFNGPKCSCGNRGCWELYASEKALLKSLQTKE
KKLSYQDIINLAHLNDIGTLNALQNFGFYLGIGLTNILNTFNPQAVILRNSIIESHPMVLNSMRSEVSSRVYSQLGNSYE
LLPSSLGQNAPALGMSSIVIDHFLDMITM

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=272, Percent_Identity=28.3088235294118, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI298566325, Length=272, Percent_Identity=28.3088235294118, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI190014632, Length=272, Percent_Identity=28.3088235294118, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4885285, Length=272, Percent_Identity=28.3088235294118, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI298566312, Length=127, Percent_Identity=34.6456692913386, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786891, Length=358, Percent_Identity=24.5810055865922, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1787878, Length=332, Percent_Identity=24.3975903614458, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081733, Length=216, Percent_Identity=28.7037037037037, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790522, Length=259, Percent_Identity=25.4826254826255, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787363, Length=237, Percent_Identity=24.4725738396624, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082127, Length=193, Percent_Identity=26.4248704663212, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 38406; Mature: 38274

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLNKSTVSSQVNTLMKESMVFEIGQGQSSGGRRPVMLVFNKKAGYSVGIDVGVDYING
CCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCCEEEHHHCHHHHHH
ILTDLEGTIVLDQYRHLESNSPEITKDILIDMIHHFITQMPQSPYGLIGIGICVPGLIDK
HHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCCCC
DQKIVFTPNSNWRDIDLKSSIQEKYNVPVFIENEANAGAYGEKVFGAAKNHDNIIYVSIS
CCEEEECCCCCCEECCHHHHHHHHCCCCEEEECCCCCCCCCHHHHCCCCCCCCEEEEEEE
TGIGIGVIINNHLYRGVSGFSGEMGHMTIDFNGPKCSCGNRGCWELYASEKALLKSLQTK
CCCEEEEEECCCHHCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EKKLSYQDIINLAHLNDIGTLNALQNFGFYLGIGLTNILNTFNPQAVILRNSIIESHPMV
HHHCCHHHHHHHHHCCCCHHHHHHHHCCEEEEHHHHHHHHCCCCCEEEEEHHHHHCCHHH
LNSMRSEVSSRVYSQLGNSYELLPSSLGQNAPALGMSSIVIDHFLDMITM
HHHHHHHHHHHHHHHCCCCEECCHHHHCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGLNKSTVSSQVNTLMKESMVFEIGQGQSSGGRRPVMLVFNKKAGYSVGIDVGVDYING
CCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCCEEEHHHCHHHHHH
ILTDLEGTIVLDQYRHLESNSPEITKDILIDMIHHFITQMPQSPYGLIGIGICVPGLIDK
HHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCCCC
DQKIVFTPNSNWRDIDLKSSIQEKYNVPVFIENEANAGAYGEKVFGAAKNHDNIIYVSIS
CCEEEECCCCCCEECCHHHHHHHHCCCCEEEECCCCCCCCCHHHHCCCCCCCCEEEEEEE
TGIGIGVIINNHLYRGVSGFSGEMGHMTIDFNGPKCSCGNRGCWELYASEKALLKSLQTK
CCCEEEEEECCCHHCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EKKLSYQDIINLAHLNDIGTLNALQNFGFYLGIGLTNILNTFNPQAVILRNSIIESHPMV
HHHCCHHHHHHHHHCCCCHHHHHHHHCCEEEEHHHHHHHHCCCCCEEEEEHHHHHCCHHH
LNSMRSEVSSRVYSQLGNSYELLPSSLGQNAPALGMSSIVIDHFLDMITM
HHHHHHHHHHHHHHHCCCCEECCHHHHCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]