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The map label for this gene is rocE

Identifier: 16081085

GI number: 16081085

Start: 4142675

End: 4144078

Strand: Reverse

Name: rocE

Synonym: BSU40330

Alternate gene names: 16081085

Gene position: 4144078-4142675 (Counterclockwise)

Preceding gene: 16081086

Following gene: 16081084

Centisome position: 98.3

GC content: 47.72

Gene sequence:

>1404_bases
GTGAATACAAACCAAGATAACGGAAATCAGCTCCAGCGGACAATGAAATCACGCCATTTGTTCATGATTTCATTGGGCGG
AGTGATCGGAACCGGTTTCTTCCTTGGAACCGGGTTTACCATTAACCAAGCGGGACCGCTCGGCGCGGTTCTGTCCTATT
TAGTGGGCGGCTTTATCATGTTTTTGACCATGCTCTGCTTAGGAGAGCTGGCAGTCGCCTTTCCTGTGTCGGGGTCCTTC
CAGACCTATGCCACGAAATTTATCAGCCCGGCCTTCGGGTTTGCGTTCGGCTGGCTGTACTGGCTCGGCTGGGCGGTTAC
ATGCGCCATTGAATTTTTATCAGCGGGGCAGCTGATGCAACGCTGGTTTCCGCATATAGACGTGTGGATCTGGTGTCTGG
TCTTTGCGGCACTGATGTTTATTTTAAATGCGATCACCACAAAAGCCTTTGCGGAATCTGAATTCTGGTTCTCAGGCATT
AAAATTTTGATTATCCTTTTATTTATTATTCTCGGCGGAGCTGCCATGTTTGGCCTGATTGATCTGAAGGGCGGAGAGCA
GGCGCCGTTTTTGACACATTTTTATGAAGACGGGTTATTTCCGAACGGCATAAAGGCAATGCTGATTACGATGATTACTG
TGAACTTTGCGTTTCAGGGGACTGAGCTGATCGGGGTTGCAGCCGGAGAAAGTGAAGACCCTGAAAAAACGATTCCGCGG
TCCATCAAACAGACAGTATGGAGAACGCTTGTGTTCTTTGTGCTTTCAATCATTGTCATTGCCGGCATGATTCCGTGGAA
ACAGGCGGGTGTCGTGGAAAGTCCATTTGTTGCCGTATTTGAGCAAATCGGAATCCCATATGCAGCTGATATCATGAACT
TTGTTATTTTAATCGCACTGTTATCTGTTGCGAACTCAGGTTTATACGCATCAACACGTATTCTGTACGCGATGGCGAAT
GAAGGACAAGCCTTCAAAGCGCTTGGCAAAACAAATCAGCGCGGTGTACCGATGTACTCGTTAATCGTAACGATGGCTGT
GGCCTGCCTATCACTTCTGACAAAGTTTGCGCAGGCTGAAACCGTATATATGGTACTGTTATCTTTGGCGGGCATGAGCG
CGCAGGTCGGCTGGATTACGATCTCGCTTTCCCAAATCATGTTCAGACGCAAATATATCCGTGAGGGCGGGAAGATAGAA
GATTTGAAATTTAAAACACCGCTGTACCCGGTGCTTCCGCTGATCGGCCTAACGTTAAATACGGTCGTGCTCATCAGTCT
TGCATTTGATCCGGAGCAGCGTATCGCGCTGTATTGCGGCGTACCGTTTATGATCATTTGCTACATCATTTATCATGTCG
TCATTAAAAAACGCCAGCAGGCAAATCGTCAGCTAGAGCTTTAA

Upstream 100 bases:

>100_bases
TATATTAAATAGATAGAGACTCTTTGGACAGCAAACTGGGATAGCACCATGCAGATGTTCCAGCTTAGATCCAATACAAG
TTGCTGAAGGGGTGCAGAAT

Downstream 100 bases:

>100_bases
AAACGTTGTCCGCAAGTCATCTTTGTTATAACCCGCATAGGACATTATCTTAAATGTTGAGGTGGAATCACAGATGGATA
AAACGATTTCGGTTATTGGA

Product: arginine/ornithine/gamma-aminobutyrate permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MNTNQDNGNQLQRTMKSRHLFMISLGGVIGTGFFLGTGFTINQAGPLGAVLSYLVGGFIMFLTMLCLGELAVAFPVSGSF
QTYATKFISPAFGFAFGWLYWLGWAVTCAIEFLSAGQLMQRWFPHIDVWIWCLVFAALMFILNAITTKAFAESEFWFSGI
KILIILLFIILGGAAMFGLIDLKGGEQAPFLTHFYEDGLFPNGIKAMLITMITVNFAFQGTELIGVAAGESEDPEKTIPR
SIKQTVWRTLVFFVLSIIVIAGMIPWKQAGVVESPFVAVFEQIGIPYAADIMNFVILIALLSVANSGLYASTRILYAMAN
EGQAFKALGKTNQRGVPMYSLIVTMAVACLSLLTKFAQAETVYMVLLSLAGMSAQVGWITISLSQIMFRRKYIREGGKIE
DLKFKTPLYPVLPLIGLTLNTVVLISLAFDPEQRIALYCGVPFMIICYIIYHVVIKKRQQANRQLEL

Sequences:

>Translated_467_residues
MNTNQDNGNQLQRTMKSRHLFMISLGGVIGTGFFLGTGFTINQAGPLGAVLSYLVGGFIMFLTMLCLGELAVAFPVSGSF
QTYATKFISPAFGFAFGWLYWLGWAVTCAIEFLSAGQLMQRWFPHIDVWIWCLVFAALMFILNAITTKAFAESEFWFSGI
KILIILLFIILGGAAMFGLIDLKGGEQAPFLTHFYEDGLFPNGIKAMLITMITVNFAFQGTELIGVAAGESEDPEKTIPR
SIKQTVWRTLVFFVLSIIVIAGMIPWKQAGVVESPFVAVFEQIGIPYAADIMNFVILIALLSVANSGLYASTRILYAMAN
EGQAFKALGKTNQRGVPMYSLIVTMAVACLSLLTKFAQAETVYMVLLSLAGMSAQVGWITISLSQIMFRRKYIREGGKIE
DLKFKTPLYPVLPLIGLTLNTVVLISLAFDPEQRIALYCGVPFMIICYIIYHVVIKKRQQANRQLEL
>Mature_467_residues
MNTNQDNGNQLQRTMKSRHLFMISLGGVIGTGFFLGTGFTINQAGPLGAVLSYLVGGFIMFLTMLCLGELAVAFPVSGSF
QTYATKFISPAFGFAFGWLYWLGWAVTCAIEFLSAGQLMQRWFPHIDVWIWCLVFAALMFILNAITTKAFAESEFWFSGI
KILIILLFIILGGAAMFGLIDLKGGEQAPFLTHFYEDGLFPNGIKAMLITMITVNFAFQGTELIGVAAGESEDPEKTIPR
SIKQTVWRTLVFFVLSIIVIAGMIPWKQAGVVESPFVAVFEQIGIPYAADIMNFVILIALLSVANSGLYASTRILYAMAN
EGQAFKALGKTNQRGVPMYSLIVTMAVACLSLLTKFAQAETVYMVLLSLAGMSAQVGWITISLSQIMFRRKYIREGGKIE
DLKFKTPLYPVLPLIGLTLNTVVLISLAFDPEQRIALYCGVPFMIICYIIYHVVIKKRQQANRQLEL

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family

Homologues:

Organism=Homo sapiens, GI110347453, Length=353, Percent_Identity=23.7960339943343, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI181337167, Length=362, Percent_Identity=22.9281767955801, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI258614003, Length=384, Percent_Identity=23.4375, Blast_Score=66, Evalue=9e-11,
Organism=Homo sapiens, GI258614005, Length=384, Percent_Identity=23.4375, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87081708, Length=466, Percent_Identity=47.4248927038627, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1788480, Length=469, Percent_Identity=39.8720682302772, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1786302, Length=463, Percent_Identity=35.4211663066955, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1786789, Length=409, Percent_Identity=37.4083129584352, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI48994972, Length=466, Percent_Identity=35.1931330472103, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI1786602, Length=462, Percent_Identity=35.4978354978355, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1789017, Length=453, Percent_Identity=32.8918322295806, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI87081915, Length=462, Percent_Identity=33.5497835497836, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1790653, Length=474, Percent_Identity=32.4894514767932, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87082250, Length=466, Percent_Identity=23.3905579399142, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87081869, Length=204, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=364, Percent_Identity=23.0769230769231, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=480, Percent_Identity=25.4166666666667, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320772, Length=483, Percent_Identity=32.2981366459627, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6324061, Length=433, Percent_Identity=31.8706697459584, Blast_Score=254, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6324553, Length=406, Percent_Identity=33.743842364532, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6324059, Length=482, Percent_Identity=30.9128630705394, Blast_Score=217, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6320717, Length=422, Percent_Identity=29.8578199052133, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6321629, Length=419, Percent_Identity=31.0262529832936, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6319824, Length=430, Percent_Identity=29.5348837209302, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6324990, Length=495, Percent_Identity=28.8888888888889, Blast_Score=212, Evalue=9e-56,
Organism=Saccharomyces cerevisiae, GI6321053, Length=462, Percent_Identity=28.3549783549784, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6322892, Length=412, Percent_Identity=32.2815533980583, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6320251, Length=419, Percent_Identity=30.0715990453461, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324924, Length=483, Percent_Identity=28.9855072463768, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6319542, Length=419, Percent_Identity=30.3102625298329, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6319543, Length=409, Percent_Identity=28.6063569682152, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6322967, Length=478, Percent_Identity=28.2426778242678, Blast_Score=189, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6324981, Length=485, Percent_Identity=28.0412371134021, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319608, Length=428, Percent_Identity=25.4672897196262, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320364, Length=557, Percent_Identity=23.6983842010772, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24667468, Length=409, Percent_Identity=24.2053789731051, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI221512776, Length=350, Percent_Identity=22.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666159, Length=350, Percent_Identity=22.5714285714286, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ROCE_BACSU (P39137)

Other databases:

- EMBL:   X81802
- EMBL:   D78193
- EMBL:   AL009126
- PIR:   S55794
- RefSeq:   NP_391913.1
- ProteinModelPortal:   P39137
- EnsemblBacteria:   EBBACT00000003763
- GeneID:   937761
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU40330
- NMPDR:   fig|224308.1.peg.4039
- GenoList:   BSU40330
- GeneTree:   EBGT00070000031926
- HOGENOM:   HBG492579
- OMA:   WLGWAVT
- PhylomeDB:   P39137
- ProtClustDB:   CLSK888187
- BioCyc:   BSUB:BSU40330-MONOMER
- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 51635; Mature: 51635

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x40c001b4)-; HASH(0x13892314)-; HASH(0x13403364)-; HASH(0x137911c4)-; HASH(0xe3cc6d4)-; HASH(0x133a7a0c)-; HASH(0x13602110)-; HASH(0xe3cc374)-; HASH(0x12729550)-; HASH(0x12dd2a50)-; HASH(0xe3cc74c)-; HASH(0xf0b5484)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNQDNGNQLQRTMKSRHLFMISLGGVIGTGFFLGTGFTINQAGPLGAVLSYLVGGFIM
CCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHH
FLTMLCLGELAVAFPVSGSFQTYATKFISPAFGFAFGWLYWLGWAVTCAIEFLSAGQLMQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWFPHIDVWIWCLVFAALMFILNAITTKAFAESEFWFSGIKILIILLFIILGGAAMFGLI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
DLKGGEQAPFLTHFYEDGLFPNGIKAMLITMITVNFAFQGTELIGVAAGESEDPEKTIPR
ECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCHHHHHH
SIKQTVWRTLVFFVLSIIVIAGMIPWKQAGVVESPFVAVFEQIGIPYAADIMNFVILIAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LSVANSGLYASTRILYAMANEGQAFKALGKTNQRGVPMYSLIVTMAVACLSLLTKFAQAE
HHHHCCCCCHHHHEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TVYMVLLSLAGMSAQVGWITISLSQIMFRRKYIREGGKIEDLKFKTPLYPVLPLIGLTLN
HHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEECEECCCCHHHHHHHHHHHHH
TVVLISLAFDPEQRIALYCGVPFMIICYIIYHVVIKKRQQANRQLEL
HHHHEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MNTNQDNGNQLQRTMKSRHLFMISLGGVIGTGFFLGTGFTINQAGPLGAVLSYLVGGFIM
CCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHH
FLTMLCLGELAVAFPVSGSFQTYATKFISPAFGFAFGWLYWLGWAVTCAIEFLSAGQLMQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWFPHIDVWIWCLVFAALMFILNAITTKAFAESEFWFSGIKILIILLFIILGGAAMFGLI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
DLKGGEQAPFLTHFYEDGLFPNGIKAMLITMITVNFAFQGTELIGVAAGESEDPEKTIPR
ECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCHHHHHH
SIKQTVWRTLVFFVLSIIVIAGMIPWKQAGVVESPFVAVFEQIGIPYAADIMNFVILIAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LSVANSGLYASTRILYAMANEGQAFKALGKTNQRGVPMYSLIVTMAVACLSLLTKFAQAE
HHHHCCCCCHHHHEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TVYMVLLSLAGMSAQVGWITISLSQIMFRRKYIREGGKIEDLKFKTPLYPVLPLIGLTLN
HHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEECEECCCCHHHHHHHHHHHHH
TVVLISLAFDPEQRIALYCGVPFMIICYIIYHVVIKKRQQANRQLEL
HHHHEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377