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The map label for this gene is ahpF

Identifier: 16081062

GI number: 16081062

Start: 4119527

End: 4121056

Strand: Direct

Name: ahpF

Synonym: BSU40100

Alternate gene names: 16081062

Gene position: 4119527-4121056 (Clockwise)

Preceding gene: 16081061

Following gene: 16081065

Centisome position: 97.72

GC content: 47.91

Gene sequence:

>1530_bases
TTGGTACTTGATGCAAATATCAAAGCACAATTAAATCAATATATGCAGCTAATTGAGAATGACATTGTTCTCAAAGTTAG
CGCAGGCGAAGATGACACTTCTAAGGACATGCTGGCTCTCGTTGATGAGCTGGCTTCCATGTCATCGAAAATTTCAGTTG
AAAAAGCTGAATTAAACAGAACGCCGAGCTTCAGTGTCAATCGTGTCGGAGAAGACACTGGCGTGACTTTCGCCGGTATC
CCTCTGGGCCACGAATTCACATCATTAGTGTTGGCGTTGCTCCAAGTGAGCGGCAGACCGCCTAAGGTAGACCAAAAAGT
CATTGATCAGGTGAAGAAGATCAGTGGTGAATACCACTTCGAATCTTATATCAGCCTGACATGCCACAACTGTCCTGATG
TTGTACAAGCTTTAAACATGATGAGCGTGCTGAACCCGAACATTACGCACACGATGATTGACGGTGCAGCATACAAAGCA
GAAGTTGAAAGCAAAAACATCATGGCAGTGCCGACCGTTTACCTGAATGGCGAATCCTTCGGAAGCGGCCGTATGACGCT
TGAAGAAATTCTTGCGAAAATGGGCAGCGGCACAGATGCATCTGAGTTTGCTGACAAAGAGCCGTTTGACGTTCTTGTGG
TCGGAGGCGGACCTGCTGGTGCAAGTGCAGCGATCTACACTGCACGTAAAGGCATCCGAACTGGTGTTGTCGCTGAGCGC
TTCGGCGGACAGGTTCTCGACACCATGAGCATCGAAAACTTCATCAGCGTCAAAGCGACGGAAGGACCGAAGCTAGCGGC
AAGTCTTGAAGAGCATGTGAAGGAATATGATATTGATGTCATGAACCTTCAGCGTGCGAAACGCCTTGAGAAGAAAGATC
TGTTCGAACTTGAACTCGAAAACGGCGCTGTCCTGAAAAGTAAAACAGTGATCCTTTCAACAGGTGCACGCTGGCGCAAT
GTCAACGTCCCCGGTGAACAAGAGTTCAAAAACAAAGGTGTCGCATACTGCCCGCACTGTGATGGGCCATTGTTTGAAGG
CAAAGACGTTGCGGTAATCGGCGGCGGAAACTCTGGTATCGAAGCAGCGATTGATCTTGCAGGTATTGTCAATCACGTTA
CTGTACTAGAATTCGCGCCGGAACTGAAAGCAGACGAAGTCCTGCAAAAACGTCTCTACAGCCTGCCTAACGTTACTGTC
GTGAAAAACGCACAAACAAAAGAAATCACAGGTGATCAGAGTGTTAACGGCATCACATATGTAGACCGCGAAACAGGCGA
AGAAAAACACGTTGAACTTCAAGGTGTATTCGTCCAAATCGGTCTCGTGCCAAACACAGAATGGTTAGAAGGAACGGTTG
AACGCAACCGCATGGGCGAAATTATTGTCGACAAACACGGCGCAACAAGCGTACCAGGCTTATTTGCTGCCGGCGACTGC
ACAGACAGTGCGTACAACCAAATTATTATTTCTATGGGATCAGGTGCAACTGCCGCCCTCGGCGCGTTTGATTACCTAAT
CCGTAACTAA

Upstream 100 bases:

>100_bases
CAAAACCCAGGTGAAGTTTGCCCGGCTAAATGGGAAGAAGGCGGCGAAACTCTTACACCTAGCCTTGATCTAGTAGGTAA
AATCTAAGGAGTGCATTCAA

Downstream 100 bases:

>100_bases
TATAAGAAATCCGCTATATTGCCAGATTGGCAGGATAGCGGATTTTTCTTTTTCTACAGAAAAAAACCGAACCAGGCACT
ACGGTAAAAGTGCTCGATTC

Product: alkyl hydroperoxide reductase large subunit

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MVLDANIKAQLNQYMQLIENDIVLKVSAGEDDTSKDMLALVDELASMSSKISVEKAELNRTPSFSVNRVGEDTGVTFAGI
PLGHEFTSLVLALLQVSGRPPKVDQKVIDQVKKISGEYHFESYISLTCHNCPDVVQALNMMSVLNPNITHTMIDGAAYKA
EVESKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGTDASEFADKEPFDVLVVGGGPAGASAAIYTARKGIRTGVVAER
FGGQVLDTMSIENFISVKATEGPKLAASLEEHVKEYDIDVMNLQRAKRLEKKDLFELELENGAVLKSKTVILSTGARWRN
VNVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADEVLQKRLYSLPNVTV
VKNAQTKEITGDQSVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLEGTVERNRMGEIIVDKHGATSVPGLFAAGDC
TDSAYNQIIISMGSGATAALGAFDYLIRN

Sequences:

>Translated_509_residues
MVLDANIKAQLNQYMQLIENDIVLKVSAGEDDTSKDMLALVDELASMSSKISVEKAELNRTPSFSVNRVGEDTGVTFAGI
PLGHEFTSLVLALLQVSGRPPKVDQKVIDQVKKISGEYHFESYISLTCHNCPDVVQALNMMSVLNPNITHTMIDGAAYKA
EVESKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGTDASEFADKEPFDVLVVGGGPAGASAAIYTARKGIRTGVVAER
FGGQVLDTMSIENFISVKATEGPKLAASLEEHVKEYDIDVMNLQRAKRLEKKDLFELELENGAVLKSKTVILSTGARWRN
VNVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADEVLQKRLYSLPNVTV
VKNAQTKEITGDQSVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLEGTVERNRMGEIIVDKHGATSVPGLFAAGDC
TDSAYNQIIISMGSGATAALGAFDYLIRN
>Mature_509_residues
MVLDANIKAQLNQYMQLIENDIVLKVSAGEDDTSKDMLALVDELASMSSKISVEKAELNRTPSFSVNRVGEDTGVTFAGI
PLGHEFTSLVLALLQVSGRPPKVDQKVIDQVKKISGEYHFESYISLTCHNCPDVVQALNMMSVLNPNITHTMIDGAAYKA
EVESKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGTDASEFADKEPFDVLVVGGGPAGASAAIYTARKGIRTGVVAER
FGGQVLDTMSIENFISVKATEGPKLAASLEEHVKEYDIDVMNLQRAKRLEKKDLFELELENGAVLKSKTVILSTGARWRN
VNVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADEVLQKRLYSLPNVTV
VKNAQTKEITGDQSVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLEGTVERNRMGEIIVDKHGATSVPGLFAAGDC
TDSAYNQIIISMGSGATAALGAFDYLIRN

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

COG id: COG3634

COG function: function code O; Alkyl hydroperoxide reductase, large subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Escherichia coli, GI87081763, Length=517, Percent_Identity=56.6731141199226, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=34.7266881028939, Blast_Score=161, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6321898, Length=310, Percent_Identity=33.2258064516129, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=310, Percent_Identity=34.1935483870968, Blast_Score=150, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHNA_BACSU (P42974)

Other databases:

- EMBL:   D78193
- EMBL:   AL009126
- EMBL:   L19710
- PIR:   G69583
- RefSeq:   NP_391890.1
- ProteinModelPortal:   P42974
- SMR:   P42974
- PhosSite:   P42974
- EnsemblBacteria:   EBBACT00000000102
- GeneID:   937717
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU40100
- NMPDR:   fig|224308.1.peg.4016
- GenoList:   BSU40100
- GeneTree:   EBGT00050000000432
- HOGENOM:   HBG289531
- OMA:   MMAAINP
- PhylomeDB:   P42974
- ProtClustDB:   PRK15317
- BioCyc:   BSUB:BSU40100-MONOMER
- BRENDA:   1.6.99.3
- GO:   GO:0006810
- InterPro:   IPR012081
- InterPro:   IPR013027
- InterPro:   IPR002109
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- PIRSF:   PIRSF000238
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR03140

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; SSF52833 Thiordxn-like_fd

EC number: =1.6.99.3

Molecular weight: Translated: 54875; Mature: 54875

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS51354 GLUTAREDOXIN_2; PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLDANIKAQLNQYMQLIENDIVLKVSAGEDDTSKDMLALVDELASMSSKISVEKAELNR
CEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCEEEHHHCCC
TPSFSVNRVGEDTGVTFAGIPLGHEFTSLVLALLQVSGRPPKVDQKVIDQVKKISGEYHF
CCCCCEECCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEE
ESYISLTCHNCPDVVQALNMMSVLNPNITHTMIDGAAYKAEVESKNIMAVPTVYLNGESF
EEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCEEEEEEEEECCCCC
GSGRMTLEEILAKMGSGTDASEFADKEPFDVLVVGGGPAGASAAIYTARKGIRTGVVAER
CCCCCHHHHHHHHHCCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCHHCHHHHH
FGGQVLDTMSIENFISVKATEGPKLAASLEEHVKEYDIDVMNLQRAKRLEKKDLFELELE
HCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEC
NGAVLKSKTVILSTGARWRNVNVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGI
CCEEEEECEEEEECCCCEEECCCCCHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCCCH
EAAIDLAGIVNHVTVLEFAPELKADEVLQKRLYSLPNVTVVKNAQTKEITGDQSVNGITY
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEE
VDRETGEEKHVELQGVFVQIGLVPNTEWLEGTVERNRMGEIIVDKHGATSVPGLFAAGDC
EECCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCC
TDSAYNQIIISMGSGATAALGAFDYLIRN
CCCCCCEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVLDANIKAQLNQYMQLIENDIVLKVSAGEDDTSKDMLALVDELASMSSKISVEKAELNR
CEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCEEEHHHCCC
TPSFSVNRVGEDTGVTFAGIPLGHEFTSLVLALLQVSGRPPKVDQKVIDQVKKISGEYHF
CCCCCEECCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEE
ESYISLTCHNCPDVVQALNMMSVLNPNITHTMIDGAAYKAEVESKNIMAVPTVYLNGESF
EEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCEEEEEEEEECCCCC
GSGRMTLEEILAKMGSGTDASEFADKEPFDVLVVGGGPAGASAAIYTARKGIRTGVVAER
CCCCCHHHHHHHHHCCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCHHCHHHHH
FGGQVLDTMSIENFISVKATEGPKLAASLEEHVKEYDIDVMNLQRAKRLEKKDLFELELE
HCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEC
NGAVLKSKTVILSTGARWRNVNVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGI
CCEEEEECEEEEECCCCEEECCCCCHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCCCH
EAAIDLAGIVNHVTVLEFAPELKADEVLQKRLYSLPNVTVVKNAQTKEITGDQSVNGITY
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEE
VDRETGEEKHVELQGVFVQIGLVPNTEWLEGTVERNRMGEIIVDKHGATSVPGLFAAGDC
EECCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCC
TDSAYNQIIISMGSGATAALGAFDYLIRN
CCCCCCEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8125345; 8180695