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The map label for this gene is ywlE

Identifier: 16080746

GI number: 16080746

Start: 3791805

End: 3792257

Strand: Reverse

Name: ywlE

Synonym: BSU36930

Alternate gene names: 16080746

Gene position: 3792257-3791805 (Counterclockwise)

Preceding gene: 16080747

Following gene: 16080745

Centisome position: 89.96

GC content: 45.25

Gene sequence:

>453_bases
ATGGATATTATTTTTGTCTGTACTGGAAATACGTGCCGCAGCCCAATGGCTGAGGCGCTTTTTAAATCAATTGCAGAAAG
GGAAGGGCTGAATGTCAATGTCCGCTCGGCAGGCGTGTTTGCTTCACCTAATGGGAAAGCGACGCCTCATGCAGTCGAAG
CGCTGTTTGAAAAACACATTGCCCTTAATCATGTGTCTTCTCCATTAACTGAAGAACTTATGGAATCGGCTGATTTGGTT
CTGGCTATGACCCATCAGCACAAACAGATCATTGCCAGCCAATTTGGACGTTATCGTGATAAAGTGTTTACGTTAAAAGA
ATATGTCACAGGCAGCCATGGTGATGTCCTCGATCCGTTCGGCGGCTCAATTGACATCTATAAACAAACGCGAGATGAGC
TTGAAGAGCTTCTTCGGCAGCTGGCAAAACAGCTGAAAAAAGACCGTAGATAA

Upstream 100 bases:

>100_bases
ATTAAAGCTGCTTTTGCCAATTTAATATACCAATAAAAGAAACGAAGTCGCCGTTTCTTTTTTCTTCATATATAATAGAG
AAAAATAAGGGGTGACTGAC

Downstream 100 bases:

>100_bases
GTTGTCAGAAAATCTGCAAACAGGTCATTTGCAAATCCTGCGTGAAGGAGTAGAATATAGTGAAAAGCACATCATATGGT
GTGAATCAAAGAGCGGACAG

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MDIIFVCTGNTCRSPMAEALFKSIAEREGLNVNVRSAGVFASPNGKATPHAVEALFEKHIALNHVSSPLTEELMESADLV
LAMTHQHKQIIASQFGRYRDKVFTLKEYVTGSHGDVLDPFGGSIDIYKQTRDELEELLRQLAKQLKKDRR

Sequences:

>Translated_150_residues
MDIIFVCTGNTCRSPMAEALFKSIAEREGLNVNVRSAGVFASPNGKATPHAVEALFEKHIALNHVSSPLTEELMESADLV
LAMTHQHKQIIASQFGRYRDKVFTLKEYVTGSHGDVLDPFGGSIDIYKQTRDELEELLRQLAKQLKKDRR
>Mature_150_residues
MDIIFVCTGNTCRSPMAEALFKSIAEREGLNVNVRSAGVFASPNGKATPHAVEALFEKHIALNHVSSPLTEELMESADLV
LAMTHQHKQIIASQFGRYRDKVFTLKEYVTGSHGDVLDPFGGSIDIYKQTRDELEELLRQLAKQLKKDRR

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWLE_BACSU (P39155)

Other databases:

- EMBL:   Z38002
- EMBL:   AL009126
- PIR:   I40479
- RefSeq:   NP_391574.1
- PDB:   1ZGG
- PDBsum:   1ZGG
- ProteinModelPortal:   P39155
- SMR:   P39155
- MINT:   MINT-7148489
- PptaseDB:   P3D0507170
- EnsemblBacteria:   EBBACT00000003939
- GeneID:   937021
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU36930
- NMPDR:   fig|224308.1.peg.3700
- GenoList:   BSU36930
- GeneTree:   EBGT00070000032142
- HOGENOM:   HBG730979
- OMA:   DKVFTLK
- PhylomeDB:   P39155
- ProtClustDB:   CLSK888045
- BioCyc:   BSUB:BSU36930-MONOMER
- BRENDA:   3.1.3.48
- InterPro:   IPR000106
- InterPro:   IPR017867
- PANTHER:   PTHR11717
- PRINTS:   PR00719
- SMART:   SM00226

Pfam domain/function: PF01451 LMWPc; SSF52788 Tyr_Pase_low_mol_wt

EC number: =3.1.3.48

Molecular weight: Translated: 16785; Mature: 16785

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: ACT_SITE 7-7 ACT_SITE 13-13 ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIFVCTGNTCRSPMAEALFKSIAEREGLNVNVRSAGVFASPNGKATPHAVEALFEKHI
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHHHHHHHH
ALNHVSSPLTEELMESADLVLAMTHQHKQIIASQFGRYRDKVFTLKEYVTGSHGDVLDPF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GGSIDIYKQTRDELEELLRQLAKQLKKDRR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIIFVCTGNTCRSPMAEALFKSIAEREGLNVNVRSAGVFASPNGKATPHAVEALFEKHI
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHHHHHHHH
ALNHVSSPLTEELMESADLVLAMTHQHKQIIASQFGRYRDKVFTLKEYVTGSHGDVLDPF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GGSIDIYKQTRDELEELLRQLAKQLKKDRR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7798145; 9384377