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The map label for this gene is ywoG

Identifier: 16080698

GI number: 16080698

Start: 3749487

End: 3750677

Strand: Direct

Name: ywoG

Synonym: BSU36450

Alternate gene names: 16080698

Gene position: 3749487-3750677 (Clockwise)

Preceding gene: 16080697

Following gene: 16080704

Centisome position: 88.94

GC content: 45.51

Gene sequence:

>1191_bases
TTGAAAAAAGCGGATGCGATATGGACCAAGGATTTTATTATGGTCCTGCTTGTCAATTTATTTGTGTTTGTGTTCTTTTA
TACATTTTTAACTGTATTGCCGATCTATACACTGCAAGAGCTTGGCGGCACAGAATCACAAGGCGGGCTTTTAATCAGCC
TGTTCCTTCTGTCTGCGATCATTACACGGCCTTTCTCCGGAGCCATCGTTGAGCGTTTCGGGAAGAAAAGAATGGCGATT
GTATCAATGGCGCTCTTCGCCCTATCATCTTTTCTGTATATGCCGATTCATAACTTTTCCCTGCTGCTCGGATTGCGGTT
CTTCCAAGGGATTTGGTTCAGCATTTTAACGACTGTTACAGGTGCAATTGCCGCTGATATTATTCCAGCCAAACGGCGCG
GTGAAGGGCTTGGATACTTTGCCATGTCTATGAACCTCGCTATGGCGATCGGGCCTTTCCTTGGCCTGAATTTGATGAGA
GTGGTAAGCTTTCCTGTATTCTTTACAGCCTTTGCGCTGTTTATGGTTGCGGGCTTACTTGTTTCGTTCTTGATAAAAGT
GCCGCAAAGTAAGGACAGCGGCACGACTGTATTCCGTTTTGCGTTCTCGGATATGTTTGAAAAGGGCGCACTCAAAATTG
CGACGGTCGGTTTGTTTATTTCTTTCTGTTATTCAACAGTCACATCATATCTGTCTGTATTCGCCAAATCAGTTGACCTT
TCGGATATCAGCGGATATTTCTTTGTTTGTTTTGCGGTGACAATGATGATTGCACGCCCGTTCACAGGGAAATTGTTCGA
CAAAGTCGGACCGGGCATTGTCATTTATCCATCAATCCTGATTTTCTCTGTCGGACTCTGCATGCTGTCCTTCACACATA
GCGGCTTAATGCTTCTGCTTTCAGGGGCGGTTATCGGTCTTGGCTACGGATCAATCGTTCCTTGCATGCAAACATTGGCG
ATTCAGAAATCTCCGGCTCACCGCTCCGGTTTTGCGACGGCAACGTTCTTTACCTTCTTTGACAGCGGAATTGCTGTAGG
ATCGTATGTATTCGGATTGTTTGTAGCATCTGCCGGCTTCTCTGCCATTTATTTAACAGCGGGGCTGTTCGTTTTAATTG
CTCTGCTTCTCTACACGTGGAGCCAGAAAAAACCTGCAGAGGCTGAAGGAAAAGTGTCTATTGCAGAATAA

Upstream 100 bases:

>100_bases
GGAAGAGCTGCTTGCAGATTTCCGGGATGAAGATAAAGAAGCTTTTTCTCATTTATTCCGCATGTTTTTACAACAATGAA
AATAAGGAAGTGACATACAT

Downstream 100 bases:

>100_bases
CTTGTCAGACTGCCGGGAAATCCCGGCAGTCTTTTTTCCATTAAAACACGGCGCCCTCTCGGTTGAACGAGAGAACGCCG
CTTATAGCAATTATTCAATG

Product: efflux transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKKADAIWTKDFIMVLLVNLFVFVFFYTFLTVLPIYTLQELGGTESQGGLLISLFLLSAIITRPFSGAIVERFGKKRMAI
VSMALFALSSFLYMPIHNFSLLLGLRFFQGIWFSILTTVTGAIAADIIPAKRRGEGLGYFAMSMNLAMAIGPFLGLNLMR
VVSFPVFFTAFALFMVAGLLVSFLIKVPQSKDSGTTVFRFAFSDMFEKGALKIATVGLFISFCYSTVTSYLSVFAKSVDL
SDISGYFFVCFAVTMMIARPFTGKLFDKVGPGIVIYPSILIFSVGLCMLSFTHSGLMLLLSGAVIGLGYGSIVPCMQTLA
IQKSPAHRSGFATATFFTFFDSGIAVGSYVFGLFVASAGFSAIYLTAGLFVLIALLLYTWSQKKPAEAEGKVSIAE

Sequences:

>Translated_396_residues
MKKADAIWTKDFIMVLLVNLFVFVFFYTFLTVLPIYTLQELGGTESQGGLLISLFLLSAIITRPFSGAIVERFGKKRMAI
VSMALFALSSFLYMPIHNFSLLLGLRFFQGIWFSILTTVTGAIAADIIPAKRRGEGLGYFAMSMNLAMAIGPFLGLNLMR
VVSFPVFFTAFALFMVAGLLVSFLIKVPQSKDSGTTVFRFAFSDMFEKGALKIATVGLFISFCYSTVTSYLSVFAKSVDL
SDISGYFFVCFAVTMMIARPFTGKLFDKVGPGIVIYPSILIFSVGLCMLSFTHSGLMLLLSGAVIGLGYGSIVPCMQTLA
IQKSPAHRSGFATATFFTFFDSGIAVGSYVFGLFVASAGFSAIYLTAGLFVLIALLLYTWSQKKPAEAEGKVSIAE
>Mature_396_residues
MKKADAIWTKDFIMVLLVNLFVFVFFYTFLTVLPIYTLQELGGTESQGGLLISLFLLSAIITRPFSGAIVERFGKKRMAI
VSMALFALSSFLYMPIHNFSLLLGLRFFQGIWFSILTTVTGAIAADIIPAKRRGEGLGYFAMSMNLAMAIGPFLGLNLMR
VVSFPVFFTAFALFMVAGLLVSFLIKVPQSKDSGTTVFRFAFSDMFEKGALKIATVGLFISFCYSTVTSYLSVFAKSVDL
SDISGYFFVCFAVTMMIARPFTGKLFDKVGPGIVIYPSILIFSVGLCMLSFTHSGLMLLLSGAVIGLGYGSIVPCMQTLA
IQKSPAHRSGFATATFFTFFDSGIAVGSYVFGLFVASAGFSAIYLTAGLFVLIALLLYTWSQKKPAEAEGKVSIAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

Organism=Escherichia coli, GI1787291, Length=404, Percent_Identity=24.5049504950495, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082270, Length=382, Percent_Identity=25.3926701570681, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWOG_BACSU (P94577)

Other databases:

- EMBL:   Z82987
- EMBL:   AL009126
- PIR:   B70065
- RefSeq:   NP_391526.1
- ProteinModelPortal:   P94577
- EnsemblBacteria:   EBBACT00000001056
- GeneID:   936928
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU36450
- NMPDR:   fig|224308.1.peg.3652
- GenoList:   BSU36450
- GeneTree:   EBGT00070000031965
- HOGENOM:   HBG534250
- OMA:   IAADIIP
- ProtClustDB:   CLSK888023
- BioCyc:   BSUB:BSU36450-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 43081; Mature: 43081

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe669c2c)-; HASH(0x12b3f4c0)-; HASH(0x12b021f8)-; HASH(0x128a4a68)-; HASH(0x12dd4ff8)-; HASH(0x12dbbb80)-; HASH(0x12dd8780)-; HASH(0x12b805b8)-; HASH(0x12e586e4)-; HASH(0x126905dc)-; HASH(0xe439264)-; HASH(0x12df45fc)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377