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The map label for this gene is sdhB

Identifier: 16079895

GI number: 16079895

Start: 2905571

End: 2906332

Strand: Reverse

Name: sdhB

Synonym: BSU28430

Alternate gene names: 16079895

Gene position: 2906332-2905571 (Counterclockwise)

Preceding gene: 255767656

Following gene: 16079894

Centisome position: 68.94

GC content: 46.59

Gene sequence:

>762_bases
ATGAGTGAACAAAAAACCATACGATTTATTATCACACGTCAAGATACAGCTGACAGCACGCCTTATGATGAAGAATTTGA
GATTCCATACCGCCCGAATCTGAACGTCATTTCCGCTCTGATGGAAATCCGCCGGAATCCGGTTAATGTCAAAGGTGAGA
AGACAACCCCTGTCACATGGGATATGAACTGTCTTGAGGAAGTATGCGGCGCATGTTCAATGGTTATAAACGGAAAACCC
CGCCAGTCTTGTACGGCGCTTATTGACCAGCTTGAACAGCCAATCCGTTTAAAACCAATGAAAACATTCCCAGTCGTTCG
TGATTTGCAGGTTGATCGCAGCAGAATGTTTGATTCATTGAAAAAAGTAAAAGCGTGGATACCGATTGACGGTACGTACG
ATTTAGGACCGGGGCCGAGAATGCCGGAAAAACGTCGTCAATGGGCATATGAATTATCAAAATGCATGACATGCGGCGTC
TGCCTCGAAGCTTGCCCGAATGTGAACAGCAAATCGAAGTTCATGGGGCCTGCACCGATGTCGCAAGTCCGCCTGTTTAA
CGCGCATCCGACAGGCGCCATGAATAAATCTGAACGATTAGAAGCATTAATGGATGAAGGCGGCCTTGCAGATTGCGGCA
ACTCGCAAAACTGTGTTCAATCCTGTCCGAAGGGGATTCCGCTTACCACTTCGATTGCAGCCTTGAATAGAGATACAAAC
TTACAAGCGTTCCGCAATTTCTTCGGAAGCGACAGAGTATAA

Upstream 100 bases:

>100_bases
GCCCGTATGAAGCGCCGGAATTTGAGTATCAGGATGTCGATGTATCACTGATAACGCCTCGGAAACGGGATTACTCGAAG
AAGAAGGTGGCGAAATAATC

Downstream 100 bases:

>100_bases
GAAGAAAAAACCTCTTCCGCATGGGAGAGGTTTTTTTAAACAATAAGGAGATGAAAAAAGATGAAGCTTCCCGCTTATAT
TGATATGCCGTTTCAAGAAT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRRNPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKP
RQSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGV
CLEACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSCPKGIPLTTSIAALNRDTN
LQAFRNFFGSDRV

Sequences:

>Translated_253_residues
MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRRNPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKP
RQSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGV
CLEACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSCPKGIPLTTSIAALNRDTN
LQAFRNFFGSDRV
>Mature_252_residues
SEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRRNPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPR
QSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVC
LEACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSCPKGIPLTTSIAALNRDTNL
QAFRNFFGSDRV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain

Homologues:

Organism=Homo sapiens, GI115387094, Length=240, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1790596, Length=234, Percent_Identity=25.6410256410256, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786943, Length=240, Percent_Identity=28.75, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17533915, Length=182, Percent_Identity=25.2747252747253, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322987, Length=245, Percent_Identity=25.3061224489796, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643156, Length=194, Percent_Identity=28.3505154639175, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17137106, Length=243, Percent_Identity=26.3374485596708, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHSB_BACSU (P08066)

Other databases:

- EMBL:   M13470
- EMBL:   Z75208
- EMBL:   AL009126
- EMBL:   M17642
- PIR:   B27763
- RefSeq:   NP_390721.1
- ProteinModelPortal:   P08066
- SMR:   P08066
- EnsemblBacteria:   EBBACT00000000867
- GeneID:   937460
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28430
- NMPDR:   fig|224308.1.peg.2846
- GenoList:   BSU28430
- GeneTree:   EBGT00050000002568
- HOGENOM:   HBG616382
- OMA:   MEIQRNP
- ProtClustDB:   PRK08640
- BioCyc:   BSUB:BSU28430-MONOMER
- BRENDA:   1.3.99.1
- GO:   GO:0006810
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489
- Gene3D:   G3DSA:3.10.20.30
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR00384

Pfam domain/function: SSF54292 Ferredoxin; SSF46548 Helical_ferredxn

EC number: =1.3.99.1

Molecular weight: Translated: 28418; Mature: 28287

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRRNPVNVKGEKTTPVTW
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEE
DMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFDSL
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHH
KKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLEACPNVNSKSKFMGPAPM
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
SQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSCPKGIPLTTSIAALNRDTN
HHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCC
LQAFRNFFGSDRV
HHHHHHHHCCCCC
>Mature Secondary Structure 
SEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRRNPVNVKGEKTTPVTW
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEE
DMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFDSL
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHH
KKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLEACPNVNSKSKFMGPAPM
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
SQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSCPKGIPLTTSIAALNRDTN
HHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCC
LQAFRNFFGSDRV
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423