Click here to switch to the map view.

The map label for this gene is cdsA

Identifier: 16078717

GI number: 16078717

Start: 1722000

End: 1722809

Strand: Direct

Name: cdsA

Synonym: BSU16540

Alternate gene names: 16078717

Gene position: 1722000-1722809 (Clockwise)

Preceding gene: 16078716

Following gene: 255767375

Centisome position: 40.85

GC content: 40.49

Gene sequence:

>810_bases
ATGGTGGACATGAAACAAAGAATTTTGACAGGTGTTCTGGCAGCAATTGTATTTTTATTTTTGGTTATTGTCGGGAAATT
GCCGTTCACCATATTAATTTATGCTATGGGCAGTGTGGCGCTTTTTGAACTTTTACGGATGAAAAAGCTGAAGCTGGTTT
CACTGCCGGGTTTGATCGGTCTTTTATTATTGTGGATGTTCTTATTACCAAGCCAGTATTCGTTTTTTGAAGCGGACGGG
ATTTCCAAAATGGAAATCGCTTTATTTGCGGTACTGCTATTGCTGACTTACACAGTGTTGGTCAAGAACACCTTTACTTT
TGATGAAGTCGGGTTTATTACGCTTGCAGCAATTTACATCGGAATGTGTTTTCATTATTTTATCGAAATCAGAAATCTTG
ACCAATACGGATTAACATACATTTTTTATGCGTGTGTTGTCATTTGGTCCACCGATTCCGGTGCCTATTTTGTCGGTAAA
TCGCTTGGGAAGCGGAAACTGTGGCCTGAAATCAGTCCGAATAAAACAGTGGAAGGGTTTGCAGGCGGAATTGTCATCGC
ACTTGTATTGGCGACGATTTTTCAGCTTGTTGCACAACTTCCGATCCCGTATATCTATCTGCTGTTGATCACGCTGTTTT
TGTCTGTTTTTGGACAACTGGGAGATTTAGTGGAATCCGCCTTGAAAAGACATTACGATGTAAAGGATTCTGGGAATATT
CTTCCCGGGCATGGCGGTATATTAGACCGTTTTGACAGTTTCTTGTTTGTCATGCCTTTCTTGTACTTTCTGCTTGCCCT
TTTTTCATAA

Upstream 100 bases:

>100_bases
CTTTACTGACGTCTTGTGGCCTGACTTTAAAGAAGATCACTTCTTGCAGGCGTTAGGAGAGTTTCAGCAGAGAGGCCGGA
GGTTTGGCGGAATTTAGAGG

Downstream 100 bases:

>100_bases
AAAAGTCTAATATGAATATGAGACTGATCATGCAGCAATAAGAATAGGAGTAGTGGCAACTTTGAAAAATATTTGTCTTT
TAGGAGCAACAGGATCAATC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MVDMKQRILTGVLAAIVFLFLVIVGKLPFTILIYAMGSVALFELLRMKKLKLVSLPGLIGLLLLWMFLLPSQYSFFEADG
ISKMEIALFAVLLLLTYTVLVKNTFTFDEVGFITLAAIYIGMCFHYFIEIRNLDQYGLTYIFYACVVIWSTDSGAYFVGK
SLGKRKLWPEISPNKTVEGFAGGIVIALVLATIFQLVAQLPIPYIYLLLITLFLSVFGQLGDLVESALKRHYDVKDSGNI
LPGHGGILDRFDSFLFVMPFLYFLLALFS

Sequences:

>Translated_269_residues
MVDMKQRILTGVLAAIVFLFLVIVGKLPFTILIYAMGSVALFELLRMKKLKLVSLPGLIGLLLLWMFLLPSQYSFFEADG
ISKMEIALFAVLLLLTYTVLVKNTFTFDEVGFITLAAIYIGMCFHYFIEIRNLDQYGLTYIFYACVVIWSTDSGAYFVGK
SLGKRKLWPEISPNKTVEGFAGGIVIALVLATIFQLVAQLPIPYIYLLLITLFLSVFGQLGDLVESALKRHYDVKDSGNI
LPGHGGILDRFDSFLFVMPFLYFLLALFS
>Mature_269_residues
MVDMKQRILTGVLAAIVFLFLVIVGKLPFTILIYAMGSVALFELLRMKKLKLVSLPGLIGLLLLWMFLLPSQYSFFEADG
ISKMEIALFAVLLLLTYTVLVKNTFTFDEVGFITLAAIYIGMCFHYFIEIRNLDQYGLTYIFYACVVIWSTDSGAYFVGK
SLGKRKLWPEISPNKTVEGFAGGIVIALVLATIFQLVAQLPIPYIYLLLITLFLSVFGQLGDLVESALKRHYDVKDSGNI
LPGHGGILDRFDSFLFVMPFLYFLLALFS

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family

Homologues:

Organism=Escherichia coli, GI87081696, Length=188, Percent_Identity=36.7021276595745, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787677, Length=116, Percent_Identity=46.551724137931, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDSA_BACSU (O31752)

Other databases:

- EMBL:   AL009126
- PIR:   G69597
- RefSeq:   NP_389536.1
- ProteinModelPortal:   O31752
- EnsemblBacteria:   EBBACT00000000065
- GeneID:   939607
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU16540
- NMPDR:   fig|224308.1.peg.1657
- GenoList:   BSU16540
- GeneTree:   EBGT00050000000669
- HOGENOM:   HBG732679
- OMA:   NIGIIHY
- PhylomeDB:   O31752
- ProtClustDB:   CLSK887312
- BioCyc:   BSUB:BSU16540-MONOMER
- BRENDA:   2.7.7.41
- InterPro:   IPR000374

Pfam domain/function: PF01148 CTP_transf_1

EC number: =2.7.7.41

Molecular weight: Translated: 30212; Mature: 30212

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb631a0c)-; HASH(0xf09b028)-; HASH(0xf1cd224)-; HASH(0xf083510)-; HASH(0xe1d0c2c)-; HASH(0xf38c2b4)-; HASH(0xf3899d8)-; HASH(0xee4aee8)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure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CCCCCCHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377