| Definition | Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome. |
|---|---|
| Accession | NC_000964 |
| Length | 4,215,606 |
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The map label for this gene is dxr
Identifier: 255767375
GI number: 255767375
Start: 1722871
End: 1724022
Strand: Direct
Name: dxr
Synonym: BSU16550
Alternate gene names: 255767375
Gene position: 1722871-1724022 (Clockwise)
Preceding gene: 16078717
Following gene: 16078719
Centisome position: 40.87
GC content: 42.71
Gene sequence:
>1152_bases TTGAAAAATATTTGTCTTTTAGGAGCAACAGGATCAATCGGCGAACAGACTCTTGATGTACTGCGTGCACATCAAGACCA ATTTCAGCTGGTATCTATGTCGTTTGGCAGAAATATTGATAAGGCCGTTCCAATGATTGAGGTCTTTCAGCCGAAGTTTG TCTCTGTCGGTGATCTGGATACATATCATAAATTAAAACAAATGTCTTTTTCTTTTGAATGCCAAATCGGGCTGGGAGAA GAAGGACTGATAGAAGCAGCAGTGATGGAGGAGGTTGACATTGTTGTCAACGCTTTGCTTGGAAGCGTCGGTCTTATCCC GACATTAAAGGCAATTGAACAGAAAAAAACAATTGCGCTTGCAAATAAGGAAACTCTTGTCACTGCAGGGCATATAGTAA AAGAACATGCTAAGAAATATGATGTTCCGCTGCTGCCTGTTGACAGTGAGCATTCAGCCATTTTTCAAGCTCTTCAAGGC GAACAGGCTAAAAACATTGAACGCCTCATCATTACGGCATCCGGCGGAAGTTTTCGGGACAAGACGCGGGAGGAGCTCGA ATCAGTAACGGTTGAAGATGCATTAAAACATCCAAACTGGTCAATGGGTGCAAAAATTACAATTGATTCGGCTACAATGA TGAATAAGGGATTAGAGGTGATCGAGGCACACTGGCTTTTCGATATACCTTATGAACAAATTGATGTGGTTTTACATAAG GAGAGCATCATCCATTCAATGGTTGAGTTCCATGATAAAAGTGTGATCGCACAGCTCGGAACTCCGGATATGAGAGTCCC CATTCAATATGCGCTCACTTATCCTGACCGATTGCCATTACCAGATGCGAAAAGGCTTGAATTATGGGAAATCGGCAGCC TTCATTTTGAGAAAGCTGATTTTGACAGGTTCCGATGCTTACAATTTGCTTTTGAATCAGGTAAAATAGGAGGAACAATG CCGACAGTGCTAAATGCGGCAAACGAAGTAGCTGTCGCTGCCTTTTTAGCTGGCAAGATACCGTTTTTGGCTATTGAAGA CTGTATCGAAAAGGCACTAACCCGCCATCAATTACTGAAAAAACCGAGCCTGGCGGACATTCAAGAAGTGGACAAAGATA CCCGGGGATACGTCAATTCAATACTCACATAA
Upstream 100 bases:
>100_bases ATGCCTTTCTTGTACTTTCTGCTTGCCCTTTTTTCATAAAAAAGTCTAATATGAATATGAGACTGATCATGCAGCAATAA GAATAGGAGTAGTGGCAACT
Downstream 100 bases:
>100_bases GGTGGTATGTTCGTGAATACAGTTATAGCGTTTATCATTATTTTCGGAACGCTCGTTTTCTTCCATGAACTGGGCCATTT ATTGCTAGCCCAAAGAGCGG
Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Products: NA
Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase
Number of amino acids: Translated: 383; Mature: 383
Protein sequence:
>383_residues MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVPMIEVFQPKFVSVGDLDTYHKLKQMSFSFECQIGLGE EGLIEAAVMEEVDIVVNALLGSVGLIPTLKAIEQKKTIALANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQG EQAKNIERLIITASGGSFRDKTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDIPYEQIDVVLHK ESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPDRLPLPDAKRLELWEIGSLHFEKADFDRFRCLQFAFESGKIGGTM PTVLNAANEVAVAAFLAGKIPFLAIEDCIEKALTRHQLLKKPSLADIQEVDKDTRGYVNSILT
Sequences:
>Translated_383_residues MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVPMIEVFQPKFVSVGDLDTYHKLKQMSFSFECQIGLGE EGLIEAAVMEEVDIVVNALLGSVGLIPTLKAIEQKKTIALANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQG EQAKNIERLIITASGGSFRDKTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDIPYEQIDVVLHK ESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPDRLPLPDAKRLELWEIGSLHFEKADFDRFRCLQFAFESGKIGGTM PTVLNAANEVAVAAFLAGKIPFLAIEDCIEKALTRHQLLKKPSLADIQEVDKDTRGYVNSILT >Mature_383_residues MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVPMIEVFQPKFVSVGDLDTYHKLKQMSFSFECQIGLGE EGLIEAAVMEEVDIVVNALLGSVGLIPTLKAIEQKKTIALANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQG EQAKNIERLIITASGGSFRDKTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDIPYEQIDVVLHK ESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPDRLPLPDAKRLELWEIGSLHFEKADFDRFRCLQFAFESGKIGGTM PTVLNAANEVAVAAFLAGKIPFLAIEDCIEKALTRHQLLKKPSLADIQEVDKDTRGYVNSILT
Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COG id: COG0743
COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DXR family
Homologues:
Organism=Escherichia coli, GI1786369, Length=387, Percent_Identity=41.0852713178295, Blast_Score=289, Evalue=2e-79,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DXR_BACSU (O31753)
Other databases:
- EMBL: AL009126 - PIR: B69881 - RefSeq: NP_389537.2 - ProteinModelPortal: O31753 - SMR: O31753 - EnsemblBacteria: EBBACT00000001985 - GeneID: 939636 - GenomeReviews: AL009126_GR - KEGG: bsu:BSU16550 - NMPDR: fig|224308.1.peg.1658 - GenoList: BSU16550 - GeneTree: EBGT00050000001768 - HOGENOM: HBG430762 - ProtClustDB: PRK05447 - BioCyc: BSUB:BSU16550-MONOMER - BRENDA: 1.1.1.267 - HAMAP: MF_00183 - InterPro: IPR003821 - InterPro: IPR013644 - InterPro: IPR013512 - InterPro: IPR016040 - Gene3D: G3DSA:3.40.50.720 - PIRSF: PIRSF006205 - TIGRFAMs: TIGR00243
Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom
EC number: =1.1.1.267
Molecular weight: Translated: 42538; Mature: 42538
Theoretical pI: Translated: 5.18; Mature: 5.18
Prosite motif: NA
Important sites: BINDING 123-123 BINDING 150-150 BINDING 174-174 BINDING 197-197 BINDING 219-219
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVPMIEVFQPKFVSVGDLD CCCEEEEECCCCCHHHHHHHHHHHHHHHEEHHHHHCCCHHHHCCHHHHCCCCCEEECCCH TYHKLKQMSFSFECQIGLGEEGLIEAAVMEEVDIVVNALLGSVGLIPTLKAIEQKKTIAL HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEE ANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQGEQAKNIERLIITASGGSFRD ECCCCEEHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCHH KTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDIPYEQIDVVLHK HHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHCCHHHEEEHEEEECCHHHHHHHHHH ESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPDRLPLPDAKRLELWEIGSLHFEKAD HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCEECCCC FDRFRCLQFAFESGKIGGTMPTVLNAANEVAVAAFLAGKIPFLAIEDCIEKALTRHQLLK HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC KPSLADIQEVDKDTRGYVNSILT CCCCHHHHHHCHHHHHHHHHHCC >Mature Secondary Structure MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVPMIEVFQPKFVSVGDLD CCCEEEEECCCCCHHHHHHHHHHHHHHHEEHHHHHCCCHHHHCCHHHHCCCCCEEECCCH TYHKLKQMSFSFECQIGLGEEGLIEAAVMEEVDIVVNALLGSVGLIPTLKAIEQKKTIAL HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEE ANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQGEQAKNIERLIITASGGSFRD ECCCCEEHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCHH KTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDIPYEQIDVVLHK HHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHCCHHHEEEHEEEECCHHHHHHHHHH ESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPDRLPLPDAKRLELWEIGSLHFEKAD HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCEECCCC FDRFRCLQFAFESGKIGGTMPTVLNAANEVAVAAFLAGKIPFLAIEDCIEKALTRHQLLK HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC KPSLADIQEVDKDTRGYVNSILT CCCCHHHHHHCHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377