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The map label for this gene is ykpA

Identifier: 16078507

GI number: 16078507

Start: 1512373

End: 1513995

Strand: Direct

Name: ykpA

Synonym: BSU14430

Alternate gene names: 16078507

Gene position: 1512373-1513995 (Clockwise)

Preceding gene: 16078505

Following gene: 16078508

Centisome position: 35.88

GC content: 43.93

Gene sequence:

>1623_bases
ATGATTGCTGTAAATAATGTAAGCTTGCGGTTTGCGGATCGCAAGTTATTTGAAGATGTTAATATTAAATTTACCCCAGG
CAACTGCTATGGGTTAATTGGTGCAAACGGTGCCGGTAAATCAACGTTTCTAAAGGTGCTGTCAGGCGAAATCGAGCCTC
AGACAGGCGACGTGCATATGAGTCCTGGCGAGCGTCTTGCCGTCTTGAAGCAGAACCATTTTGAGTACGAAGAGTATGAA
GTGCTGAAAGTGGTCATTATGGGCCACAAACGCCTGTATGAAGTCATGCAGGAGAAAGACGCTATTTACATGAAGCCTGA
TTTCTCAGATGAGGATGGGATTCGTGCTGCTGAGCTAGAAGGTGAATTCGCGGAACTGAACGGTTGGGAAGCGGAAAGTG
AAGCTGCGATCCTGTTAAAAGGCCTTGGTATCTCAGAAGATCTGCACACAAAAAAGATGGCAGACCTCGGCGGTTCGGAG
AAGGTAAAAGTTCTCTTGGCACAGGCATTATTCGGCAAGCCGGATGTTCTGCTGCTCGATGAGCCGACGAACCACCTGGA
CCTTCAGGCAATTCAGTGGCTTGAAGAGTTTCTGATTAACTTTGAAAACACAGTTATTGTCGTATCCCATGACCGTCACT
TTTTAAATAAAGTATGTACGCACATTGCCGACCTTGATTTTAACAAAATTCAAATCTATGTCGGAAACTATGATTTCTGG
TACGAGTCAAGCCAGCTGGCGTTAAAGCTTTCTCAAGAAGCGAACAAGAAAAAAGAAGAGCAGATTAAACAGCTTCAAGA
GTTTGTCGCTAGATTCAGCGCCAATGCGTCTAAATCTAAGCAGGCTACATCAAGAAAGAAACTTCTCGAAAAAATCACGC
TGGATGATATTAAACCGTCTTCCCGCCGCTATCCTTATGTTAACTTCACGCCGGAACGGGAAATCGGAAATGATGTTCTT
CGCGTGGAAGGCTTAACAAAAACAATCGATGGCGTAAAGGTGCTTGACAATGTCAGCTTTATTATGAATCGAGAAGATAA
AATTGCTTTCACTGGCCGAAATGAACTTGCTGTTACTACGCTGTTTAAAATCATTTCCGGGGAAATGGAAGCTGACAGCG
GAACGTTTAAATGGGGTGTTACCACATCTCAAGCGTATTTTCCAAAAGACAACAGCGAATATTTCGAAGGCAGTGATCTG
AACCTTGTAGACTGGCTTCGCCAATATTCTCCGCACGACCAAAGTGAGAGCTTTTTACGCGGTTTCTTAGGACGCATGCT
GTTCTCTGGAGAAGAAGTCCACAAAAAAGCAAATGTACTTTCCGGGGGAGAAAAGGTCCGCTGTATGCTGTCGAAAGCGA
TGCTTTCTGGCGCCAATATTTTAATTTTGGATGAGCCGACCAACCATTTAGACCTAGAGTCCATTACAGCGCTCAATAAC
GGCTTAATCAGCTTTAAAGGCGCTATGCTGTTTACTTCCCATGACCATCAGTTTGTGCAGACCATTGCCAACAGAATTAT
AGAAATTACACCTAACGGCATCGTCGATAAGCAAATGAGCTATGACGAGTTCCTTGAAAATGCTGATGTGCAGAAAAAAT
TGACTGAACTATACGCCGAATAA

Upstream 100 bases:

>100_bases
GTGTATAAGTGTTTTCTCTCTGTTTTATCAGGGAATCATTTCTCTTGCCCTGCATTCATGGTATACTTTTATTGATGATA
GACATGATGGAGGATAATAA

Downstream 100 bases:

>100_bases
AAAAGCAGAGATTTCTCTGCTTTTTTTGATACCTAAATGTGAAAGGAGATCACAACATGAAATTTTTGGTTGTCGGAGCA
GGTGGAGTAGGCGGGTATAT

Product: ABC efflux transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MIAVNNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKVLSGEIEPQTGDVHMSPGERLAVLKQNHFEYEEYE
VLKVVIMGHKRLYEVMQEKDAIYMKPDFSDEDGIRAAELEGEFAELNGWEAESEAAILLKGLGISEDLHTKKMADLGGSE
KVKVLLAQALFGKPDVLLLDEPTNHLDLQAIQWLEEFLINFENTVIVVSHDRHFLNKVCTHIADLDFNKIQIYVGNYDFW
YESSQLALKLSQEANKKKEEQIKQLQEFVARFSANASKSKQATSRKKLLEKITLDDIKPSSRRYPYVNFTPEREIGNDVL
RVEGLTKTIDGVKVLDNVSFIMNREDKIAFTGRNELAVTTLFKIISGEMEADSGTFKWGVTTSQAYFPKDNSEYFEGSDL
NLVDWLRQYSPHDQSESFLRGFLGRMLFSGEEVHKKANVLSGGEKVRCMLSKAMLSGANILILDEPTNHLDLESITALNN
GLISFKGAMLFTSHDHQFVQTIANRIIEITPNGIVDKQMSYDEFLENADVQKKLTELYAE

Sequences:

>Translated_540_residues
MIAVNNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKVLSGEIEPQTGDVHMSPGERLAVLKQNHFEYEEYE
VLKVVIMGHKRLYEVMQEKDAIYMKPDFSDEDGIRAAELEGEFAELNGWEAESEAAILLKGLGISEDLHTKKMADLGGSE
KVKVLLAQALFGKPDVLLLDEPTNHLDLQAIQWLEEFLINFENTVIVVSHDRHFLNKVCTHIADLDFNKIQIYVGNYDFW
YESSQLALKLSQEANKKKEEQIKQLQEFVARFSANASKSKQATSRKKLLEKITLDDIKPSSRRYPYVNFTPEREIGNDVL
RVEGLTKTIDGVKVLDNVSFIMNREDKIAFTGRNELAVTTLFKIISGEMEADSGTFKWGVTTSQAYFPKDNSEYFEGSDL
NLVDWLRQYSPHDQSESFLRGFLGRMLFSGEEVHKKANVLSGGEKVRCMLSKAMLSGANILILDEPTNHLDLESITALNN
GLISFKGAMLFTSHDHQFVQTIANRIIEITPNGIVDKQMSYDEFLENADVQKKLTELYAE
>Mature_540_residues
MIAVNNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKVLSGEIEPQTGDVHMSPGERLAVLKQNHFEYEEYE
VLKVVIMGHKRLYEVMQEKDAIYMKPDFSDEDGIRAAELEGEFAELNGWEAESEAAILLKGLGISEDLHTKKMADLGGSE
KVKVLLAQALFGKPDVLLLDEPTNHLDLQAIQWLEEFLINFENTVIVVSHDRHFLNKVCTHIADLDFNKIQIYVGNYDFW
YESSQLALKLSQEANKKKEEQIKQLQEFVARFSANASKSKQATSRKKLLEKITLDDIKPSSRRYPYVNFTPEREIGNDVL
RVEGLTKTIDGVKVLDNVSFIMNREDKIAFTGRNELAVTTLFKIISGEMEADSGTFKWGVTTSQAYFPKDNSEYFEGSDL
NLVDWLRQYSPHDQSESFLRGFLGRMLFSGEEVHKKANVLSGGEKVRCMLSKAMLSGANILILDEPTNHLDLESITALNN
GLISFKGAMLFTSHDHQFVQTIANRIIEITPNGIVDKQMSYDEFLENADVQKKLTELYAE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains

Homologues:

Organism=Homo sapiens, GI148612853, Length=532, Percent_Identity=29.8872180451128, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI10947137, Length=523, Percent_Identity=30.7839388145315, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI27881506, Length=523, Percent_Identity=30.7839388145315, Blast_Score=226, Evalue=6e-59,
Organism=Homo sapiens, GI69354671, Length=517, Percent_Identity=27.6595744680851, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI10947135, Length=517, Percent_Identity=27.6595744680851, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI105990541, Length=205, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI45446740, Length=237, Percent_Identity=27.4261603375527, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI47078218, Length=237, Percent_Identity=27.4261603375527, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1787041, Length=531, Percent_Identity=45.7627118644068, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1789751, Length=542, Percent_Identity=32.2878228782288, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI2367384, Length=522, Percent_Identity=32.7586206896552, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1787182, Length=503, Percent_Identity=30.0198807157058, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1788450, Length=240, Percent_Identity=26.25, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789864, Length=244, Percent_Identity=24.5901639344262, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787029, Length=237, Percent_Identity=27.8481012658228, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790525, Length=226, Percent_Identity=27.8761061946903, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786398, Length=231, Percent_Identity=26.4069264069264, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48995001, Length=218, Percent_Identity=28.4403669724771, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87081791, Length=254, Percent_Identity=23.6220472440945, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=517, Percent_Identity=28.6266924564797, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17553372, Length=549, Percent_Identity=28.4153005464481, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17559834, Length=537, Percent_Identity=29.0502793296089, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17558664, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=520, Percent_Identity=32.5, Blast_Score=245, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6321121, Length=530, Percent_Identity=28.8679245283019, Blast_Score=203, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6325030, Length=377, Percent_Identity=25.1989389920424, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6324314, Length=370, Percent_Identity=25.1351351351351, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323278, Length=230, Percent_Identity=25.2173913043478, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666836, Length=516, Percent_Identity=30.0387596899225, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24642252, Length=516, Percent_Identity=28.6821705426357, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI18859989, Length=516, Percent_Identity=28.6821705426357, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24641342, Length=521, Percent_Identity=28.9827255278311, Blast_Score=197, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKPA_BACSU (O31716)

Other databases:

- EMBL:   AF012285
- EMBL:   AL009126
- PIR:   E69861
- RefSeq:   NP_389326.1
- ProteinModelPortal:   O31716
- EnsemblBacteria:   EBBACT00000002343
- GeneID:   936066
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14430
- NMPDR:   fig|224308.1.peg.1445
- GenoList:   BSU14430
- GeneTree:   EBGT00070000031864
- HOGENOM:   HBG758042
- OMA:   TILTARN
- PhylomeDB:   O31716
- ProtClustDB:   CLSK2484783
- BioCyc:   BSUB:BSU14430-MONOMER
- GO:   GO:0006810
- InterPro:   IPR003439
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 61056; Mature: 61056

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVNNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKVLSGEIEPQTGDVHM
CEEEECEEEEEHHHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEE
SPGERLAVLKQNHFEYEEYEVLKVVIMGHKRLYEVMQEKDAIYMKPDFSDEDGIRAAELE
CCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCCCCCEEEECC
GEFAELNGWEAESEAAILLKGLGISEDLHTKKMADLGGSEKVKVLLAQALFGKPDVLLLD
CCHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDLQAIQWLEEFLINFENTVIVVSHDRHFLNKVCTHIADLDFNKIQIYVGNYDFW
CCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALKLSQEANKKKEEQIKQLQEFVARFSANASKSKQATSRKKLLEKITLDDIKPS
ECCCCEEEEECHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SRRYPYVNFTPEREIGNDVLRVEGLTKTIDGVKVLDNVSFIMNREDKIAFTGRNELAVTT
CCCCCEEECCCCHHCCCCEEEECCCHHHHCCHHHHHCHHHEECCCCCEEEECCCCHHHHH
LFKIISGEMEADSGTFKWGVTTSQAYFPKDNSEYFEGSDLNLVDWLRQYSPHDQSESFLR
HHHHHCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
GFLGRMLFSGEEVHKKANVLSGGEKVRCMLSKAMLSGANILILDEPTNHLDLESITALNN
HHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHCC
GLISFKGAMLFTSHDHQFVQTIANRIIEITPNGIVDKQMSYDEFLENADVQKKLTELYAE
CEEEECCEEEEECCCHHHHHHHHHCEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIAVNNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKVLSGEIEPQTGDVHM
CEEEECEEEEEHHHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEE
SPGERLAVLKQNHFEYEEYEVLKVVIMGHKRLYEVMQEKDAIYMKPDFSDEDGIRAAELE
CCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCCCCCEEEECC
GEFAELNGWEAESEAAILLKGLGISEDLHTKKMADLGGSEKVKVLLAQALFGKPDVLLLD
CCHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDLQAIQWLEEFLINFENTVIVVSHDRHFLNKVCTHIADLDFNKIQIYVGNYDFW
CCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALKLSQEANKKKEEQIKQLQEFVARFSANASKSKQATSRKKLLEKITLDDIKPS
ECCCCEEEEECHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SRRYPYVNFTPEREIGNDVLRVEGLTKTIDGVKVLDNVSFIMNREDKIAFTGRNELAVTT
CCCCCEEECCCCHHCCCCEEEECCCHHHHCCHHHHHCHHHEECCCCCEEEECCCCHHHHH
LFKIISGEMEADSGTFKWGVTTSQAYFPKDNSEYFEGSDLNLVDWLRQYSPHDQSESFLR
HHHHHCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
GFLGRMLFSGEEVHKKANVLSGGEKVRCMLSKAMLSGANILILDEPTNHLDLESITALNN
HHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHCC
GLISFKGAMLFTSHDHQFVQTIANRIIEITPNGIVDKQMSYDEFLENADVQKKLTELYAE
CEEEECCEEEEECCCHHHHHHHHHCEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377