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The map label for this gene is ntdA

Identifier: 16078119

GI number: 16078119

Start: 1128286

End: 1129611

Strand: Reverse

Name: ntdA

Synonym: BSU10550

Alternate gene names: 16078119

Gene position: 1129611-1128286 (Counterclockwise)

Preceding gene: 16078121

Following gene: 255767241

Centisome position: 26.8

GC content: 34.31

Gene sequence:

>1326_bases
ATGCAAAAACAGGTTAAGATTTCAGGTAAAAGCAAAGAAAACATGTCACTATTAAAACACTTAAAAGGTGACGTACAAGG
AAAAGAACTTGTTATTGAAGACAGTATTGTAAACGAGCGGTGGAAACAAGTATTAAAAGAAAAGATAGATATTGAACATG
ACCTTTTCAACTATCAAAAAAATCGTGAAATCAGTAAAGTCCCTTTTTTGCCTGTAGACAGATTAATAACCAATGATGAA
GTGGAAGATATCTTAAATACATTAACTGAAGTTTTGCCAACTGGAAAATTTACGAGTGGTCCCTATTTAGAGCAATTCGA
AAAAGTTTTATCTACATATTTACATAAAAGGTATGTAATTGCAACCAGCAGTGGAACCGATGCTATTATGATAGGTTTAT
TGGCTTTAGGGTTAAACCCAGGGGATGAAGTTATCATGCCGGCTAATAGCTTTTCAGCTACTGAAAATGCTGTGTTAGCT
TCGGGAGGCGTTCCTATCTATGTAGATATTAACCCACAAACATTCTGCATCGATCCTGACAAAATTGAAGAAGCAATAAC
TCCTTATACAAAGTTTATTCTACCTGTGCATTTATACGGAAAACATTCAGACATGCAGCATATCCGTCAAATCGCAAATC
GTTATAAATTAAAAGTAATTGAAGATGCCTGCCAAGGAATTGGACTGACAGACTTAGGAAAGTATGCAGACATCACTACA
TTAAGTTTTAATCCCTATAAGAATTTTGGTGTATGTGGCAAGGCTGGGGCAATAGCAACTGATAATGAAGAACTCGCTAA
AAAATGCATTCAATTTAGTTATCACGGTTTTGAAGTAAATGTAAAAAATAAGAAAGTCATCAATTTTGGATTTAATTCAA
AAATGGACAATTTACAGGCAGCAATTGGTTTAGAGAGAATGAAGTACCTTTCATTAAACAACTTCAAAAGATTGTTCTTG
GCGGATAGATACATTACCCAATTAGCAGAGTTGCAGAATAAAGGCTATATTGAATTACCAGAATTAAGTGAAGATCATGT
ATGGCATCTGTTTCCTATTAAGGTAAGAACAGAAGATAGGGCAGATATCATGACTAAATTAAATGAAGATTTTGGTGTTC
AAACAGATGTATATTATCCAATACTTTCTCATATGCAAAAAACTCCTTTAGTACAGGACAAGTATGCAGGACTCCAATTG
GTTCATACGGAAAAGGCTCATAGTCAGGTACTGCATTTGCCTTTATATCCGTCATTTACTTTAGAAGAACAAGACAGAGT
AATGGAGGGACTGTTTCATGTTATTAAGCAAGAAATCGGAGTATAA

Upstream 100 bases:

>100_bases
TTCCCTTCCTTAAAAAAGTTGTTGACATGTTACCGATTTCAGAAACTAGGATAAATTTGTAATAAATTTTTAGATTATAA
AATCATTGGAGGTACTGTTC

Downstream 100 bases:

>100_bases
AACGTTATCCACGGTTGAACATCCTCAATATATTGTTTTTTGTGATTTTGATGAAACGTATTTTCCGCATACAATCGACG
AACAAAAGCAACAAGACATC

Product: neotrehalosadiamine biosynthesis aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQKNREISKVPFLPVDRLITNDE
VEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLA
SGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITT
LSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFL
ADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQL
VHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQEIGV

Sequences:

>Translated_441_residues
MQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQKNREISKVPFLPVDRLITNDE
VEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLA
SGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITT
LSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFL
ADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQL
VHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQEIGV
>Mature_441_residues
MQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQKNREISKVPFLPVDRLITNDE
VEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLA
SGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITT
LSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFL
ADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQL
VHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQEIGV

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family

Homologues:

Organism=Escherichia coli, GI145693159, Length=385, Percent_Identity=32.4675324675325, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI2367285, Length=363, Percent_Identity=29.7520661157025, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTDA_BACSU (O07566)

Other databases:

- EMBL:   Y14081
- EMBL:   AL009126
- PIR:   C69834
- RefSeq:   NP_388936.1
- ProteinModelPortal:   O07566
- SMR:   O07566
- EnsemblBacteria:   EBBACT00000002530
- GeneID:   939788
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU10550
- NMPDR:   fig|224308.1.peg.1055
- GenoList:   BSU10550
- GeneTree:   EBGT00050000001120
- HOGENOM:   HBG660897
- OMA:   VCGKAGA
- PhylomeDB:   O07566
- ProtClustDB:   CLSK887020
- BioCyc:   BSUB:BSU10550-MONOMER
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000390

Pfam domain/function: PF01041 DegT_DnrJ_EryC1; SSF53383 PyrdxlP-dep_Trfase_major

EC number: NA

Molecular weight: Translated: 50141; Mature: 50141

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQK
CCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHC
NREISKVPFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVI
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEE
ATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQTFCIDPD
EECCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEECCCEEEEEEECCCEEEECHH
KIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITT
HHHHHHCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQA
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCEEEEECCCEEEEECCCCCHHHHHH
AIGLERMKYLSLNNFKRLFLADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEEEEECCCH
ADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQLVHTEKAHSQVLHLPLYPSFT
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCC
LEEQDRVMEGLFHVIKQEIGV
CCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQK
CCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHC
NREISKVPFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVI
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEE
ATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQTFCIDPD
EECCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEECCCEEEEEEECCCEEEECHH
KIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITT
HHHHHHCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQA
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCEEEEECCCEEEEECCCCCHHHHHH
AIGLERMKYLSLNNFKRLFLADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEEEEECCCH
ADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQLVHTEKAHSQVLHLPLYPSFT
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCC
LEEQDRVMEGLFHVIKQEIGV
CCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377