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The map label for this gene is treP

Identifier: 16077847

GI number: 16077847

Start: 850367

End: 851779

Strand: Direct

Name: treP

Synonym: BSU07800

Alternate gene names: 16077847

Gene position: 850367-851779 (Clockwise)

Preceding gene: 16077842

Following gene: 16077848

Centisome position: 20.17

GC content: 48.34

Gene sequence:

>1413_bases
ATGGGGGAACTGAACAAATCGGCACGTCAGATTGTCGAAGCAGTCGGCGGTGCTGAAAATATTGCAGCGGCAACTCATTG
TGTTACACGTTTGCGTTTTGCTTTAATAGATGAAAGCAAGGTTGACCAAGAGATGCTTGATCAAATTGATGTGGTAAAGG
GATCATTCTCGACAAACGGACAGTTTCAGGTCGTAATCGGCCAGGGAACTGTCAATAAAGTATATGCTGAACTGGTTAAG
GAAACGGGGATTGGCGAGTCAACAAAGGATGAAGTGAAGAAGGCCTCAGAAAAAAATATGAATCCTTTGCAGCGTGCTGT
GAAAACGCTTGCAGATATTTTTATTCCAATATTGCCTGCGATTGTCACGGCGGGTCTTTTAATGGGGATCAATAACATTT
TAACGGCGGAAGGCATTTTCTTCAGCACAAAATCGATTGTGCAGGTTTATCCGCAGTGGGCGGATCTTGCTAATATGATT
AACCTGATTGCAGGCACGGCCTTTACGTTTTTGCCTGCGTTAATCGGATGGTCTGCCGTCAAGCGGTTCGGCGGCAATCC
GCTTCTCGGCATTGTGCTCGGGGTTATGCTCGTGCATCCTGATTTGCTGAATGCGTGGGGATATGGCGCGGCAGAACAAA
GCGGAGAGATCCCGGTATGGAATCTATTCGGCCTAGAGGTGCAGAAAGTCGGCTATCAGGGCCAGGTGCTCCCAATTTTG
CTTGCTTCTTATATGCTGGCGAAGATTGAGGTATTTTTAACAAAACGCACACCTGAGGGCATACAGCTGCTCGTTGTCGC
ACCAATTACGCTTCTCTTAACAGGATTTGCCTCTTTTATCATTATCGGCCCGATTACATTTGCGATCGGTAATGTACTGA
CTTCAGGGCTTATCTCGGTGTTTGGTTCTTTTGCCGCACTGGGCGGTCTGTTATATGGCGGTTTCTACTCAGCGCTCGTG
ATTACCGGTATGCATCACACGTTTCTTGCAGTCGACCTGCAGCTCATCGGTTCAAAGCTCGGCGGCACCTTTTTATGGCC
GATGCTGGCGCTTTCTAATATCGCACAAGGTTCGGCGGCTCTGGCCATGATGTTTATCGTGAAGGATGAGAAACAAAAAG
GCCTCTCCCTCACATCAGGGATTTCTGCTTATCTTGGCATTACAGAGCCTGCCATCTTTGGGGTGAATCTGCGATACAGA
TTCCCGTTTATCATTGCAATGGTCAGCTCTGGCCTGGCCGGAATGTATATTTCTTCTCAAGGTGTGCTGGCAAGCTCCGT
CGGTGTCGGCGGCGTGCCGGGGATTTTCTCAATCATGAGCCAGTACTGGGGCGCGTTTGCAATCGGGATGGCTATTGTAT
TGATCGTGCCGTTTGCCGGAACATACGCGTATGCGAGATTCAAACATAAATAA

Upstream 100 bases:

>100_bases
AAAGCGCTATAAAAAAGTGTTGACTACCTGTATATACAGGAATACAATATGATTATAAGTTGTATATACAAGTTATAAAA
ACGGATACGGAGGGGTTGGC

Downstream 100 bases:

>100_bases
CAAGTGGGGAGCGGGACGTGTTGAACGTTCCCTTTTCCCGTTTTCAATTTAAATATGGTGGTGGAAACAGATGAAAACAG
AACAAACGCCATGGTGGAAA

Product: phosphotransferase system (PTS) trehalose-specific enzyme IIBC component

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MGELNKSARQIVEAVGGAENIAAATHCVTRLRFALIDESKVDQEMLDQIDVVKGSFSTNGQFQVVIGQGTVNKVYAELVK
ETGIGESTKDEVKKASEKNMNPLQRAVKTLADIFIPILPAIVTAGLLMGINNILTAEGIFFSTKSIVQVYPQWADLANMI
NLIAGTAFTFLPALIGWSAVKRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPIL
LASYMLAKIEVFLTKRTPEGIQLLVVAPITLLLTGFASFIIIGPITFAIGNVLTSGLISVFGSFAALGGLLYGGFYSALV
ITGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAALAMMFIVKDEKQKGLSLTSGISAYLGITEPAIFGVNLRYR
FPFIIAMVSSGLAGMYISSQGVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIVPFAGTYAYARFKHK

Sequences:

>Translated_470_residues
MGELNKSARQIVEAVGGAENIAAATHCVTRLRFALIDESKVDQEMLDQIDVVKGSFSTNGQFQVVIGQGTVNKVYAELVK
ETGIGESTKDEVKKASEKNMNPLQRAVKTLADIFIPILPAIVTAGLLMGINNILTAEGIFFSTKSIVQVYPQWADLANMI
NLIAGTAFTFLPALIGWSAVKRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPIL
LASYMLAKIEVFLTKRTPEGIQLLVVAPITLLLTGFASFIIIGPITFAIGNVLTSGLISVFGSFAALGGLLYGGFYSALV
ITGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAALAMMFIVKDEKQKGLSLTSGISAYLGITEPAIFGVNLRYR
FPFIIAMVSSGLAGMYISSQGVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIVPFAGTYAYARFKHK
>Mature_469_residues
GELNKSARQIVEAVGGAENIAAATHCVTRLRFALIDESKVDQEMLDQIDVVKGSFSTNGQFQVVIGQGTVNKVYAELVKE
TGIGESTKDEVKKASEKNMNPLQRAVKTLADIFIPILPAIVTAGLLMGINNILTAEGIFFSTKSIVQVYPQWADLANMIN
LIAGTAFTFLPALIGWSAVKRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPILL
ASYMLAKIEVFLTKRTPEGIQLLVVAPITLLLTGFASFIIIGPITFAIGNVLTSGLISVFGSFAALGGLLYGGFYSALVI
TGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAALAMMFIVKDEKQKGLSLTSGISAYLGITEPAIFGVNLRYRF
PFIIAMVSSGLAGMYISSQGVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIVPFAGTYAYARFKHK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain

Homologues:

Organism=Escherichia coli, GI2367362, Length=455, Percent_Identity=42.1978021978022, Blast_Score=350, Evalue=9e-98,
Organism=Escherichia coli, GI1790159, Length=440, Percent_Identity=30.4545454545455, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI48994906, Length=461, Percent_Identity=27.114967462039, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788769, Length=417, Percent_Identity=28.0575539568345, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTTBC_BACSU (P39794)

Other databases:

- EMBL:   Z54245
- EMBL:   D83967
- EMBL:   D86417
- EMBL:   AL009126
- EMBL:   X80203
- PIR:   C69725
- RefSeq:   NP_388661.1
- ProteinModelPortal:   P39794
- SMR:   P39794
- EnsemblBacteria:   EBBACT00000000521
- GeneID:   939188
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU07800
- NMPDR:   fig|224308.1.peg.780
- GenoList:   BSU07800
- GeneTree:   EBGT00050000000033
- HOGENOM:   HBG673521
- OMA:   FFDGKNL
- PhylomeDB:   P39794
- ProtClustDB:   CLSK873252
- BioCyc:   BSUB:BSU07800-MONOMER
- BRENDA:   2.7.1.69
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296
- Gene3D:   G3DSA:3.30.1360.60
- TIGRFAMs:   TIGR00826
- TIGRFAMs:   TIGR00852
- TIGRFAMs:   TIGR01992

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC; SSF55604 PTS_EIIB

EC number: =2.7.1.69

Molecular weight: Translated: 50001; Mature: 49869

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS51098 PTS_EIIB_TYPE_1; PS01035 PTS_EIIB_TYPE_1_CYS; PS51103 PTS_EIIC_TYPE_1; PS00079 MULTICOPPER_OXIDASE1

Important sites: ACT_SITE 26-26

Signals:

None

Transmembrane regions:

HASH(0xdba09cc)-; HASH(0xd7ab9f8)-; HASH(0xd230fa4)-; HASH(0xb2c1df8)-; HASH(0xd835a9c)-; HASH(0xc312960)-; HASH(0xc78afe8)-; HASH(0xc98ae34)-; HASH(0xdab3064)-; HASH(0xd5827f8)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGELNKSARQIVEAVGGAENIAAATHCVTRLRFALIDESKVDQEMLDQIDVVKGSFSTNG
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCCCCC
QFQVVIGQGTVNKVYAELVKETGIGESTKDEVKKASEKNMNPLQRAVKTLADIFIPILPA
EEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IVTAGLLMGINNILTAEGIFFSTKSIVQVYPQWADLANMINLIAGTAFTFLPALIGWSAV
HHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPIL
HHCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCEEEEECCCCEECCCCCCHHHHH
LASYMLAKIEVFLTKRTPEGIQLLVVAPITLLLTGFASFIIIGPITFAIGNVLTSGLISV
HHHHHHHHHHHEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSFAALGGLLYGGFYSALVITGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHH
LAMMFIVKDEKQKGLSLTSGISAYLGITEPAIFGVNLRYRFPFIIAMVSSGLAGMYISSQ
HHHHHHEECCHHCCCCHHHCHHHHHCCCCCEEEEEEEEEHHHHHHHHHHCCCCEEEEECC
GVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIVPFAGTYAYARFKHK
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCH
>Mature Secondary Structure 
GELNKSARQIVEAVGGAENIAAATHCVTRLRFALIDESKVDQEMLDQIDVVKGSFSTNG
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCCCCC
QFQVVIGQGTVNKVYAELVKETGIGESTKDEVKKASEKNMNPLQRAVKTLADIFIPILPA
EEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IVTAGLLMGINNILTAEGIFFSTKSIVQVYPQWADLANMINLIAGTAFTFLPALIGWSAV
HHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPIL
HHCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCEEEEECCCCEECCCCCCHHHHH
LASYMLAKIEVFLTKRTPEGIQLLVVAPITLLLTGFASFIIIGPITFAIGNVLTSGLISV
HHHHHHHHHHHEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSFAALGGLLYGGFYSALVITGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHH
LAMMFIVKDEKQKGLSLTSGISAYLGITEPAIFGVNLRYRFPFIIAMVSSGLAGMYISSQ
HHHHHHEECCHHCCCCHHHCHHHHHCCCCCEEEEEEEEEHHHHHHHHHHCCCCEEEEECC
GVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIVPFAGTYAYARFKHK
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9272861; 9384377; 7651129