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The map label for this gene is lmrA

Identifier: 16077337

GI number: 16077337

Start: 290132

End: 290698

Strand: Reverse

Name: lmrA

Synonym: BSU02680

Alternate gene names: 16077337

Gene position: 290698-290132 (Counterclockwise)

Preceding gene: 16077340

Following gene: 16077336

Centisome position: 6.9

GC content: 51.15

Gene sequence:

>567_bases
ATGAGTTATGGAGATTCCCGTGAGAAAATCCTTTCGGCAGCTACCCGGCTTTTTCAGCTGCAAGGGTATTACGGCACGGG
GCTGAACCAGATTATAAAGGAAAGCGGCGCGCCTAAAGGCTCTCTTTACTACCACTTTCCCGGGGGTAAAGAACAGCTTG
CGATCGAAGCCGTGAATGAGATGAAGGAGTATATCCGTCAGAAAATCGCGGACTGCATGGAAGCCTGCACCGATCCAGCG
GAAGGCATTCAAGCCTTTTTGAAGGAGCTCTCCTGCCAGTTTTCATGTACGGAAGACATTGAAGGCTTGCCTGTGGGCTT
GCTAGCGGCTGAGACGTCATTGAAAAGCGAACCGTTGCGCGAAGCCTGTCATGAAGCCTACAAAGAATGGGCCTCTGTGT
ATGAGGAAAAACTGCGGCAGACTGGCTGCAGCGAGAGCCGTGCAAAAGAAGCCAGCACTGTGGTTAACGCGATGATTGAA
GGCGGCATCCTTTTATCTTTGACGGCAAAAAACAGTACGCCGCTCCTTCATATCTCCAGCTGCATTCCTGACCTGCTGAA
GAGATAA

Upstream 100 bases:

>100_bases
TCTTTTCATACAATGAATTTTTCTTGACAATTGATGATTGAATCAAGATAATAGACCAGTCACTATATTTTTGATTGCAA
TTCAGTAAGGTGGGAATGTT

Downstream 100 bases:

>100_bases
AAAAAACGACATACTACATGCAGTTGATAGAGAGGGGAAATGATTTTGGAAACAACAGCTAAAGCATCTCAGCAATACAA
AGTGATGCCGATTATGATTT

Product: transcriptional repressor of lmrAB and yxaGH operons

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPGGKEQLAIEAVNEMKEYIRQKIADCMEACTDPA
EGIQAFLKELSCQFSCTEDIEGLPVGLLAAETSLKSEPLREACHEAYKEWASVYEEKLRQTGCSESRAKEASTVVNAMIE
GGILLSLTAKNSTPLLHISSCIPDLLKR

Sequences:

>Translated_188_residues
MSYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPGGKEQLAIEAVNEMKEYIRQKIADCMEACTDPA
EGIQAFLKELSCQFSCTEDIEGLPVGLLAAETSLKSEPLREACHEAYKEWASVYEEKLRQTGCSESRAKEASTVVNAMIE
GGILLSLTAKNSTPLLHISSCIPDLLKR
>Mature_187_residues
SYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPGGKEQLAIEAVNEMKEYIRQKIADCMEACTDPAE
GIQAFLKELSCQFSCTEDIEGLPVGLLAAETSLKSEPLREACHEAYKEWASVYEEKLRQTGCSESRAKEASTVVNAMIEG
GILLSLTAKNSTPLLHISSCIPDLLKR

Specific function: Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): LMRA_BACSU (O34619)

Other databases:

- EMBL:   AB000617
- EMBL:   AL009126
- PIR:   D69652
- RefSeq:   NP_388150.1
- HSSP:   P42105
- ProteinModelPortal:   O34619
- SMR:   O34619
- EnsemblBacteria:   EBBACT00000000269
- GeneID:   938385
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU02680
- NMPDR:   fig|224308.1.peg.269
- GenoList:   BSU02680
- GeneTree:   EBGT00050000000418
- HOGENOM:   HBG658459
- OMA:   EACHEAY
- ProtClustDB:   CLSK886631
- BioCyc:   BSUB:BSU02680-MONOMER
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.357.10
- PRINTS:   PR00455

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like; SSF48498 TetR_like_C

EC number: NA

Molecular weight: Translated: 20663; Mature: 20532

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPGGKEQLAIEAVNE
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHH
MKEYIRQKIADCMEACTDPAEGIQAFLKELSCQFSCTEDIEGLPVGLLAAETSLKSEPLR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHH
EACHEAYKEWASVYEEKLRQTGCSESRAKEASTVVNAMIEGGILLSLTAKNSTPLLHISS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEHHH
CIPDLLKR
HHHHHHCC
>Mature Secondary Structure 
SYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPGGKEQLAIEAVNE
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHH
MKEYIRQKIADCMEACTDPAEGIQAFLKELSCQFSCTEDIEGLPVGLLAAETSLKSEPLR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHH
EACHEAYKEWASVYEEKLRQTGCSESRAKEASTVVNAMIEGGILLSLTAKNSTPLLHISS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEHHH
CIPDLLKR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377