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The map label for this gene is arsR [H]

Identifier: 15606578

GI number: 15606578

Start: 985792

End: 986100

Strand: Direct

Name: arsR [H]

Synonym: aq_1387

Alternate gene names: 15606578

Gene position: 985792-986100 (Clockwise)

Preceding gene: 15606577

Following gene: 15606579

Centisome position: 63.54

GC content: 42.39

Gene sequence:

>309_bases
ATGGATTGTAAAGAGCTTGCGAGGATTTTTTACGCCCTTTCGGAGCCAAAGAGGCTCTGTATGGTGAAGTTGCTTCTGGA
GAGAGAGGAACTTTGTGTGTGTGACTTTATGAGGATTTTTAAGGAGTCCCAACCTAAGATATCCTTTCACCTTAAGGTAT
TAAGGGAAGCGGGGCTTGTGACTTCGCAAAAAAGGGGCAAGTGGAATTATTACCGCCTTAACAAGGAAGCTCCTGTTATA
CCTTGTGTGGAAAAGCTCCTTAAAGATGTAAAGCTTGAAGAAAAAATCCAATTGGAGGTGAAGAGATGA

Upstream 100 bases:

>100_bases
AATAAGGCGGACGAGATATTCCTGCGGGGATATGAGAGCACTTTAAGAATTATGAGAAATTTCGTAAAACATTAAGAAAA
ATTTATATAAAATTTCATTT

Downstream 100 bases:

>100_bases
AGGAAATTAAGATTCTCAGCGGGACAAATTGTCAGAACTGTGAACTGCTTTATCAAGTCGTTAGCGAAATCGTAAAAAGA
AAAGGTATTGATGCGAAAGT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MDCKELARIFYALSEPKRLCMVKLLLEREELCVCDFMRIFKESQPKISFHLKVLREAGLVTSQKRGKWNYYRLNKEAPVI
PCVEKLLKDVKLEEKIQLEVKR

Sequences:

>Translated_102_residues
MDCKELARIFYALSEPKRLCMVKLLLEREELCVCDFMRIFKESQPKISFHLKVLREAGLVTSQKRGKWNYYRLNKEAPVI
PCVEKLLKDVKLEEKIQLEVKR
>Mature_102_residues
MDCKELARIFYALSEPKRLCMVKLLLEREELCVCDFMRIFKESQPKISFHLKVLREAGLVTSQKRGKWNYYRLNKEAPVI
PCVEKLLKDVKLEEKIQLEVKR

Specific function: Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=72, Percent_Identity=48.6111111111111, Blast_Score=73, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12173; Mature: 12173

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCKELARIFYALSEPKRLCMVKLLLEREELCVCDFMRIFKESQPKISFHLKVLREAGLV
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
TSQKRGKWNYYRLNKEAPVIPCVEKLLKDVKLEEKIQLEVKR
CCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCHHEEEECC
>Mature Secondary Structure
MDCKELARIFYALSEPKRLCMVKLLLEREELCVCDFMRIFKESQPKISFHLKVLREAGLV
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
TSQKRGKWNYYRLNKEAPVIPCVEKLLKDVKLEEKIQLEVKR
CCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]