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The map label for this gene is hdrC

Identifier: 11498972

GI number: 11498972

Start: 1227701

End: 1228183

Strand: Reverse

Name: hdrC

Synonym: AF1376

Alternate gene names: 11498972

Gene position: 1228183-1227701 (Counterclockwise)

Preceding gene: 11498973

Following gene: 11498971

Centisome position: 56.38

GC content: 49.69

Gene sequence:

>483_bases
ATGAGAGTTGTGAGGCTGCCAAGGCATGATGACGTTGTGGAGGAGGTTTCAAAGTTTGGTGGGGAAGGAATTGGGAGATG
CATCCAGTGCGGAGCGTGCATGTCGGTCTGCCCTGTTGCAATTGCTGGTTTCAACTTCCCCAACAAGAAGCTCTTCAAGG
TTATAACTCTCGGCCTGAGGGAGGACATTCTCTTCGACCCCTCCCCGTGGGCCTGTGTTGCGTGCGGGAGGTGCATAGAA
ATCTGCACGAGAGATGTAAACCCATTTCACGTTTACTTTGCCTTCAGAAGAATTCAGACGAGGGAATTCTCTATTCCCTC
AAGGGCTGAGGAGCTTTTGAGGAGGGTTTATACTACTGGCTTTGCCGTGCAGATTAACAACGAACTGAGAGCTGAATTCG
ACCTTCCCGAAATTGGCAGTGTGGATGAAGTTGAAAAGATCATTGAATGCACTGAGATGTCCCAGCTGGGCTTAATTCGG
TGA

Upstream 100 bases:

>100_bases
GCAAGGGGTGCGGAATCTGCAGCTCCGTCTGCCCTGCCAACGCTGTTGATTTAGCTGGATTCACAAGAGAGCAAATTCTC
TCCCAGCTGGAGGCGATATT

Downstream 100 bases:

>100_bases
GGTGTTTATGAAGTACGCTCTGTTTCCCGGCTGCAAAATTGCCTTCGAAAGGCCTGACCTTGAGCTTGCGATGAGGGAGG
TGCTCACAGCTCTCGATGTA

Product: heterodisulfide reductase, subunit C (hdrC)

Products: N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine; dihydromethanophenazine

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRVVRLPRHDDVVEEVSKFGGEGIGRCIQCGACMSVCPVAIAGFNFPNKKLFKVITLGLREDILFDPSPWACVACGRCIE
ICTRDVNPFHVYFAFRRIQTREFSIPSRAEELLRRVYTTGFAVQINNELRAEFDLPEIGSVDEVEKIIECTEMSQLGLIR

Sequences:

>Translated_160_residues
MRVVRLPRHDDVVEEVSKFGGEGIGRCIQCGACMSVCPVAIAGFNFPNKKLFKVITLGLREDILFDPSPWACVACGRCIE
ICTRDVNPFHVYFAFRRIQTREFSIPSRAEELLRRVYTTGFAVQINNELRAEFDLPEIGSVDEVEKIIECTEMSQLGLIR
>Mature_160_residues
MRVVRLPRHDDVVEEVSKFGGEGIGRCIQCGACMSVCPVAIAGFNFPNKKLFKVITLGLREDILFDPSPWACVACGRCIE
ICTRDVNPFHVYFAFRRIQTREFSIPSRAEELLRRVYTTGFAVQINNELRAEFDLPEIGSVDEVEKIIECTEMSQLGLIR

Specific function: Has oxidoreductase activity. The Hdl and Mvh subunits may together mediate electron transfer from hydrogen to an unidentified electron acceptor on the cytoplasmic side of the membrane [H]

COG id: COG1150

COG function: function code C; Heterodisulfide reductase, subunit C

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: 1.8.98.1

Molecular weight: Translated: 18131; Mature: 18131

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVRLPRHDDVVEEVSKFGGEGIGRCIQCGACMSVCPVAIAGFNFPNKKLFKVITLGLR
CCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EDILFDPSPWACVACGRCIEICTRDVNPFHVYFAFRRIQTREFSIPSRAEELLRRVYTTG
HCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
FAVQINNELRAEFDLPEIGSVDEVEKIIECTEMSQLGLIR
EEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVVRLPRHDDVVEEVSKFGGEGIGRCIQCGACMSVCPVAIAGFNFPNKKLFKVITLGLR
CCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EDILFDPSPWACVACGRCIEICTRDVNPFHVYFAFRRIQTREFSIPSRAEELLRRVYTTG
HCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
FAVQINNELRAEFDLPEIGSVDEVEKIIECTEMSQLGLIR
EEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: coenzyme B; coenzyme M; methanophenazine

Specific reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA