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The map label for this gene is hdrB

Identifier: 11498971

GI number: 11498971

Start: 1226815

End: 1227699

Strand: Reverse

Name: hdrB

Synonym: AF1375

Alternate gene names: 11498971

Gene position: 1227699-1226815 (Counterclockwise)

Preceding gene: 11498972

Following gene: 11498970

Centisome position: 56.36

GC content: 49.83

Gene sequence:

>885_bases
GTGTTTATGAAGTACGCTCTGTTTCCCGGCTGCAAAATTGCCTTCGAAAGGCCTGACCTTGAGCTTGCGATGAGGGAGGT
GCTCACAGCTCTCGATGTACCCTTTGAATACCTAAGTGACTTCTCCTGCTGTCCAACATGGGCGTCAGTTCCGTCCTTCG
ACATCGAGGCGTGGTTGGCTATTTCAGCAAGAAACATTTCCCTCGCTGAGGAGAAAGGACTGGACATTGTTGTTGGGTGT
GGAGATTGCTACAGCGTCCTGAACCATGCCAGAGACATGCTGAAAAGGGAGGAGTGGCGTGAGAGAGTGAACAGAATTCT
CGCCAAGGTTGGCAGAGTTTACAGGGGGACGACCAAGATTTACCACATAATACACCTTCTGGAGGAGCGCAAAATTAAGA
AGAACCTGAAGCACAGGCTGAATGGCTTTGTTGCAGGCGTTCAGCCCGGCTGCCATCTGCTGTGGCCAGCTAAGATTTTT
GATGCCAAAGAGGAGAATCCATTTTTCCCTGAAAGGCTGAAGAAGCTGGTGGAAGCAATGGGTGCTGAAACACCTCACTA
CAGCAGGCTTGAGTACTGCTGCGGGAACCACATTGATATTGTGGATTATGAGAAATTCCTTGATTTTGTTCAGCTGAAGC
TTCAGTCTCTGAAGGAGGAAATAGATCCTGACTTTATCGTTACCGCCTGCTCTACATGTTTCATCCAGCTTGATGAGGGG
CAGAAGAGGCTCAAGAGGCTGGGGAGGATTGACTACGAAATCCCCGTCTTCCACTTCCCCCAGCTTCTCGCCATCTGCTT
GGGCAGCAATCCGGAAAAGGTGGCGAGAATCAGCTCCGTTGACAGAAGCAAGATTATTTCGGAAATTCTGGAGGGGAGAG
AATGA

Upstream 100 bases:

>100_bases
CTGAGAGCTGAATTCGACCTTCCCGAAATTGGCAGTGTGGATGAAGTTGAAAAGATCATTGAATGCACTGAGATGTCCCA
GCTGGGCTTAATTCGGTGAG

Downstream 100 bases:

>100_bases
AAATTATCGGTTTTGCCTGTCAGTGGTGCGCCTATCAGGCCGCTGATTTGGCGGGTAGCTTGAAAATGAAGTATCCTGAA
AGCATCAGACTTCTGAGAGT

Product: heterodisulfide reductase, subunit B (hdrB)

Products: N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine; dihydromethanophenazine

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MFMKYALFPGCKIAFERPDLELAMREVLTALDVPFEYLSDFSCCPTWASVPSFDIEAWLAISARNISLAEEKGLDIVVGC
GDCYSVLNHARDMLKREEWRERVNRILAKVGRVYRGTTKIYHIIHLLEERKIKKNLKHRLNGFVAGVQPGCHLLWPAKIF
DAKEENPFFPERLKKLVEAMGAETPHYSRLEYCCGNHIDIVDYEKFLDFVQLKLQSLKEEIDPDFIVTACSTCFIQLDEG
QKRLKRLGRIDYEIPVFHFPQLLAICLGSNPEKVARISSVDRSKIISEILEGRE

Sequences:

>Translated_294_residues
MFMKYALFPGCKIAFERPDLELAMREVLTALDVPFEYLSDFSCCPTWASVPSFDIEAWLAISARNISLAEEKGLDIVVGC
GDCYSVLNHARDMLKREEWRERVNRILAKVGRVYRGTTKIYHIIHLLEERKIKKNLKHRLNGFVAGVQPGCHLLWPAKIF
DAKEENPFFPERLKKLVEAMGAETPHYSRLEYCCGNHIDIVDYEKFLDFVQLKLQSLKEEIDPDFIVTACSTCFIQLDEG
QKRLKRLGRIDYEIPVFHFPQLLAICLGSNPEKVARISSVDRSKIISEILEGRE
>Mature_294_residues
MFMKYALFPGCKIAFERPDLELAMREVLTALDVPFEYLSDFSCCPTWASVPSFDIEAWLAISARNISLAEEKGLDIVVGC
GDCYSVLNHARDMLKREEWRERVNRILAKVGRVYRGTTKIYHIIHLLEERKIKKNLKHRLNGFVAGVQPGCHLLWPAKIF
DAKEENPFFPERLKKLVEAMGAETPHYSRLEYCCGNHIDIVDYEKFLDFVQLKLQSLKEEIDPDFIVTACSTCFIQLDEG
QKRLKRLGRIDYEIPVFHFPQLLAICLGSNPEKVARISSVDRSKIISEILEGRE

Specific function: Has oxidoreductase activity. The Hdl and Mvh subunits may together mediate electron transfer from hydrogen to an unidentified electron acceptor on the cytoplasmic side of the membrane [H]

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: 1.8.98.1

Molecular weight: Translated: 33887; Mature: 33887

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMKYALFPGCKIAFERPDLELAMREVLTALDVPFEYLSDFSCCPTWASVPSFDIEAWLA
CCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHHEE
ISARNISLAEEKGLDIVVGCGDCYSVLNHARDMLKREEWRERVNRILAKVGRVYRGTTKI
EEECCCCHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YHIIHLLEERKIKKNLKHRLNGFVAGVQPGCHLLWPAKIFDAKEENPFFPERLKKLVEAM
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEECHHHHHCCCCCCCCCHHHHHHHHHHH
GAETPHYSRLEYCCGNHIDIVDYEKFLDFVQLKLQSLKEEIDPDFIVTACSTCFIQLDEG
CCCCCCHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCH
QKRLKRLGRIDYEIPVFHFPQLLAICLGSNPEKVARISSVDRSKIISEILEGRE
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFMKYALFPGCKIAFERPDLELAMREVLTALDVPFEYLSDFSCCPTWASVPSFDIEAWLA
CCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHHEE
ISARNISLAEEKGLDIVVGCGDCYSVLNHARDMLKREEWRERVNRILAKVGRVYRGTTKI
EEECCCCHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YHIIHLLEERKIKKNLKHRLNGFVAGVQPGCHLLWPAKIFDAKEENPFFPERLKKLVEAM
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEECHHHHHCCCCCCCCCHHHHHHHHHHH
GAETPHYSRLEYCCGNHIDIVDYEKFLDFVQLKLQSLKEEIDPDFIVTACSTCFIQLDEG
CCCCCCHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCH
QKRLKRLGRIDYEIPVFHFPQLLAICLGSNPEKVARISSVDRSKIISEILEGRE
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: coenzyme B; coenzyme M; methanophenazine

Specific reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA