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The map label for this gene is cbiL

Identifier: 11498334

GI number: 11498334

Start: 652450

End: 653055

Strand: Reverse

Name: cbiL

Synonym: AF0727

Alternate gene names: NA

Gene position: 653055-652450 (Counterclockwise)

Preceding gene: 11498340

Following gene: 11498333

Centisome position: 29.98

GC content: 48.02

Gene sequence:

>606_bases
ATGGCAAAACTGCTCTACGGCGTTGGAATTGGCCTGACAAAGAAGCACCTCACGCTTGAGGCTATTGATGTGATTAAGGA
AGTAGATGACGTTGTTGTGCCGGGAAAGATGGCCTACGAGGTTATTAAGGATATTAGGGAGCCGAGAGTTGTTGAGTTCC
CGATGGGGGACAGCGAGGAGGTTGTGAAAAATCTTGCAAAGGAGATTAACGAGTTCGATGGCACGGTTGCCTTCTGCTGC
ATAGGCGACCCGGTTTTCTACTCCACCTTTAACCATCTTGTGAGGGAGGTAAGGAAGCTCGACCCCAATCTGACAGTAAA
GGTAATCCCCGGAATCAGCAGCATCTCAGTTGCCCTCGCCAAAACTGAGACTTTCGTAACCAGATCCGCCTTAATTGCAA
CTCAGGATTTTAGAGATGCAGATGTTGCCGTTGTGCTGAAGGTCAAGAATCCGAGGGAGGTGGAGAGAAGGTTGAGAGAA
AAAGGTTACAACGATTTCACTCTGCTTGAAAAGCTTTTCATGAATGGGGAGAAAATTTACTGTGAAATGCCCGAGAAGTC
GAGCTACTTCAGCGTGATGGTTGCGAGGAGAGTTGAGGAGAGATGA

Upstream 100 bases:

>100_bases
CACAACACCTCCAGATTTCTTGAGCTTGTGTCAGATTGACTTTATTTAAATTTTTTGGATTTTCAGTAAGATTTATTTAA
CTGAGTTTAGAGTTGCAGCA

Downstream 100 bases:

>100_bases
AGGTTTACTTCGTGGGCTTCGGACCGGGAAATCCAGAGCTTTTAACCTTAAAGGCCTACAAACTGCTTAAGGAGGCGGAT
TTGGTAGTTTACCCCGGCTC

Product: cobalamin biosynthesis precorrin-2 methyltransferase (cbiL)

Products: S-adenosyl-L-homocysteine; Precorrin 3A

Alternate protein names: Uroporphyrin-III C/Tetrapyrrole Methyltransferase; Cobalamin Biosynthesis Precorrin-2 Methyltransferase; Cobalt-Factor II

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAKLLYGVGIGLTKKHLTLEAIDVIKEVDDVVVPGKMAYEVIKDIREPRVVEFPMGDSEEVVKNLAKEINEFDGTVAFCC
IGDPVFYSTFNHLVREVRKLDPNLTVKVIPGISSISVALAKTETFVTRSALIATQDFRDADVAVVLKVKNPREVERRLRE
KGYNDFTLLEKLFMNGEKIYCEMPEKSSYFSVMVARRVEER

Sequences:

>Translated_201_residues
MAKLLYGVGIGLTKKHLTLEAIDVIKEVDDVVVPGKMAYEVIKDIREPRVVEFPMGDSEEVVKNLAKEINEFDGTVAFCC
IGDPVFYSTFNHLVREVRKLDPNLTVKVIPGISSISVALAKTETFVTRSALIATQDFRDADVAVVLKVKNPREVERRLRE
KGYNDFTLLEKLFMNGEKIYCEMPEKSSYFSVMVARRVEER
>Mature_200_residues
AKLLYGVGIGLTKKHLTLEAIDVIKEVDDVVVPGKMAYEVIKDIREPRVVEFPMGDSEEVVKNLAKEINEFDGTVAFCCI
GDPVFYSTFNHLVREVRKLDPNLTVKVIPGISSISVALAKTETFVTRSALIATQDFRDADVAVVLKVKNPREVERRLREK
GYNDFTLLEKLFMNGEKIYCEMPEKSSYFSVMVARRVEER

Specific function: Unknown

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.130

Molecular weight: Translated: 22780; Mature: 22649

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLLYGVGIGLTKKHLTLEAIDVIKEVDDVVVPGKMAYEVIKDIREPRVVEFPMGDSEE
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCEEEECCCCHHH
VVKNLAKEINEFDGTVAFCCIGDPVFYSTFNHLVREVRKLDPNLTVKVIPGISSISVALA
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
KTETFVTRSALIATQDFRDADVAVVLKVKNPREVERRLREKGYNDFTLLEKLFMNGEKIY
HHHHHHHHHHHHEECCCCCCCEEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEE
CEMPEKSSYFSVMVARRVEER
EECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKLLYGVGIGLTKKHLTLEAIDVIKEVDDVVVPGKMAYEVIKDIREPRVVEFPMGDSEE
CCEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCEEEECCCCHHH
VVKNLAKEINEFDGTVAFCCIGDPVFYSTFNHLVREVRKLDPNLTVKVIPGISSISVALA
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
KTETFVTRSALIATQDFRDADVAVVLKVKNPREVERRLREKGYNDFTLLEKLFMNGEKIY
HHHHHHHHHHHHEECCCCCCCEEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEE
CEMPEKSSYFSVMVARRVEER
EECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 2

Specific reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + precorrin-3A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA