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Identifier: 11498045

GI number: 11498045

Start: 390093

End: 391193

Strand: Reverse

Name: Not Available

Synonym: AF0433

Alternate gene names: 11498045

Gene position: 391193-390093 (Counterclockwise)

Preceding gene: 11498046

Following gene: 11498044

Centisome position: 17.96

GC content: 49.32

Gene sequence:

>1101_bases
GTGATGCTCGTGCAGCTAAGGCAGGTAGGTGTGATAAGGTCTCCCTACAAAAACTTTAGCAAAGCTCCACATCAGGGAAG
GTTCTCCAAGGAAACAGTAGAAATCGAGATTTTCCCGGAGTTTGAGGACGGTTTGAAGGATATTGAAACCTGCACTCATC
TTATTGTCCTCTACTGGCTTGACAGAGCAAACAGGGACGCTTTGCTTGTTGTTCCTCCTCACGACAGCAGAGAACATGGA
GTCTTTGCGACCCGCTCTCCCCATCGCCCGAATCCGATTGGTTTCGCAGTTGTTGAGCTGCTTGAAAGGGATGGGAGAGT
TCTGAAGGTTAAAGGACTCGATGCTCTCGACGGCACACCAGTTGTGGATATAAAGCCGTACTCTTCTACGATAGATTCAG
TAGGAAACGCGAAAATCGGATGGTTTGAGGAGGCAAATCCTCAATCAAAGCTGACAAGGCTGCTTTTGAGGGCAAAGGAG
TTTCACGGTCACATCTGCCCCTTCGTTGCGCTCGGAGTTAGAATGTCCGTCATAGCAATGGAAAAGCTCGGAGTTGAAGA
AGATGCAATGGCGAGTGTTGGAGAGGATATTCTCGCAATAGTGGAGTGCAACAACTGCCTTACTGACGGCGTGCAGGTTG
CAACCGGATGCACGCTCGGAAACAACTCTCTGATTTACCTCGACCTTGGAAAGAATGCTCTTACTATAGTCAGAAGAAAA
GACTGGAAGGGCGTGAGAGTTTACGTAAATGCTGAGAACGTGAGGAAGTACTTCAGCAAAGAGGCTCTTGAGCTCTTTAA
CAAGGTTATAGTGAGGAGAGAGGGCAGTGAGGAGGATGCAAAGAGGCTCTCCGAGTTCTGGGAGGAGACTGGCTGGAAGA
TGCTTGAGATTCCGGAAGAGGAGTTCAAGGTTGAGTTTGTAGAGGTTCAGCCTATAGAGAGGGCACCGATTTTTGAAAAC
AAAAGGTGTGAGAAGTGCGGAGAGCTTGCAATGGCCACACGCGTTAAGGATGGTCTCTGCTTGAGGTGTGCGGGCAGCTA
CTACGCCGTTGTTGGTAGGGGGATTGTGAAGTTCGATGGAGAGATGAGGGAGGTGGTCTGA

Upstream 100 bases:

>100_bases
ATAAATTTACTGTTCTTTGTAACCTTTGGTAACACCAAAAACCAAAATTTTAATCTTCAGTCTGCCATTAGCACAGTTGT
TAGTAACACCACACAAAAAG

Downstream 100 bases:

>100_bases
ATGAGGAAGGTTTCGCTCCTTGCTCTGGCTCTGGCGATTCTGATTGCCGGCTGTGCTCAGCAGCCTGCTCAAGTTAAGGA
GGGCGGGAAGGTTACGGTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MMLVQLRQVGVIRSPYKNFSKAPHQGRFSKETVEIEIFPEFEDGLKDIETCTHLIVLYWLDRANRDALLVVPPHDSREHG
VFATRSPHRPNPIGFAVVELLERDGRVLKVKGLDALDGTPVVDIKPYSSTIDSVGNAKIGWFEEANPQSKLTRLLLRAKE
FHGHICPFVALGVRMSVIAMEKLGVEEDAMASVGEDILAIVECNNCLTDGVQVATGCTLGNNSLIYLDLGKNALTIVRRK
DWKGVRVYVNAENVRKYFSKEALELFNKVIVRREGSEEDAKRLSEFWEETGWKMLEIPEEEFKVEFVEVQPIERAPIFEN
KRCEKCGELAMATRVKDGLCLRCAGSYYAVVGRGIVKFDGEMREVV

Sequences:

>Translated_366_residues
MMLVQLRQVGVIRSPYKNFSKAPHQGRFSKETVEIEIFPEFEDGLKDIETCTHLIVLYWLDRANRDALLVVPPHDSREHG
VFATRSPHRPNPIGFAVVELLERDGRVLKVKGLDALDGTPVVDIKPYSSTIDSVGNAKIGWFEEANPQSKLTRLLLRAKE
FHGHICPFVALGVRMSVIAMEKLGVEEDAMASVGEDILAIVECNNCLTDGVQVATGCTLGNNSLIYLDLGKNALTIVRRK
DWKGVRVYVNAENVRKYFSKEALELFNKVIVRREGSEEDAKRLSEFWEETGWKMLEIPEEEFKVEFVEVQPIERAPIFEN
KRCEKCGELAMATRVKDGLCLRCAGSYYAVVGRGIVKFDGEMREVV
>Mature_366_residues
MMLVQLRQVGVIRSPYKNFSKAPHQGRFSKETVEIEIFPEFEDGLKDIETCTHLIVLYWLDRANRDALLVVPPHDSREHG
VFATRSPHRPNPIGFAVVELLERDGRVLKVKGLDALDGTPVVDIKPYSSTIDSVGNAKIGWFEEANPQSKLTRLLLRAKE
FHGHICPFVALGVRMSVIAMEKLGVEEDAMASVGEDILAIVECNNCLTDGVQVATGCTLGNNSLIYLDLGKNALTIVRRK
DWKGVRVYVNAENVRKYFSKEALELFNKVIVRREGSEEDAKRLSEFWEETGWKMLEIPEEEFKVEFVEVQPIERAPIFEN
KRCEKCGELAMATRVKDGLCLRCAGSYYAVVGRGIVKFDGEMREVV

Specific function: Unknown

COG id: COG2191

COG function: function code C; Formylmethanofuran dehydrogenase subunit E

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0066 (virR) family

Homologues:

Organism=Homo sapiens, GI118600979, Length=136, Percent_Identity=33.8235294117647, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786393, Length=156, Percent_Identity=37.8205128205128, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45552503, Length=156, Percent_Identity=34.6153846153846, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24586408, Length=137, Percent_Identity=35.7664233576642, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y433_ARCFU (O29816)

Other databases:

- EMBL:   AE000782
- PIR:   A69304
- RefSeq:   NP_069269.1
- ProteinModelPortal:   O29816
- GeneID:   1483649
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF0433
- NMPDR:   fig|224325.1.peg.428
- TIGR:   AF_0433
- HOGENOM:   HBG321675
- ProtClustDB:   CLSK2392782
- BioCyc:   AFUL224325:AF_0433-MONOMER
- InterPro:   IPR003814
- InterPro:   IPR018316
- InterPro:   IPR001378
- Gene3D:   G3DSA:3.30.1330.20
- TIGRFAMs:   TIGR00104

Pfam domain/function: PF02663 FwdE; PF01980 UPF0066

EC number: NA

Molecular weight: Translated: 41303; Mature: 41303

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS01318 UPF0066

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLVQLRQVGVIRSPYKNFSKAPHQGRFSKETVEIEIFPEFEDGLKDIETCTHLIVLYWL
CEEEEEHHHCCHHCCHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
DRANRDALLVVPPHDSREHGVFATRSPHRPNPIGFAVVELLERDGRVLKVKGLDALDGTP
CCCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCC
VVDIKPYSSTIDSVGNAKIGWFEEANPQSKLTRLLLRAKEFHGHICPFVALGVRMSVIAM
EEEEECCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EKLGVEEDAMASVGEDILAIVECNNCLTDGVQVATGCTLGNNSLIYLDLGKNALTIVRRK
HHCCCCHHHHHHHCCCEEEEEECCCHHCCCEEEEECEEECCCCEEEEECCCCEEEEEEEC
DWKGVRVYVNAENVRKYFSKEALELFNKVIVRREGSEEDAKRLSEFWEETGWKMLEIPEE
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCH
EFKVEFVEVQPIERAPIFENKRCEKCGELAMATRVKDGLCLRCAGSYYAVVGRGIVKFDG
HHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCEEEECC
EMREVV
HHHHCC
>Mature Secondary Structure
MMLVQLRQVGVIRSPYKNFSKAPHQGRFSKETVEIEIFPEFEDGLKDIETCTHLIVLYWL
CEEEEEHHHCCHHCCHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
DRANRDALLVVPPHDSREHGVFATRSPHRPNPIGFAVVELLERDGRVLKVKGLDALDGTP
CCCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCC
VVDIKPYSSTIDSVGNAKIGWFEEANPQSKLTRLLLRAKEFHGHICPFVALGVRMSVIAM
EEEEECCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EKLGVEEDAMASVGEDILAIVECNNCLTDGVQVATGCTLGNNSLIYLDLGKNALTIVRRK
HHCCCCHHHHHHHCCCEEEEEECCCHHCCCEEEEECEEECCCCEEEEECCCCEEEEEEEC
DWKGVRVYVNAENVRKYFSKEALELFNKVIVRREGSEEDAKRLSEFWEETGWKMLEIPEE
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCH
EFKVEFVEVQPIERAPIFENKRCEKCGELAMATRVKDGLCLRCAGSYYAVVGRGIVKFDG
HHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCEEEECC
EMREVV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475