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The map label for this gene is desR

Identifier: 11497861

GI number: 11497861

Start: 221060

End: 221638

Strand: Reverse

Name: desR

Synonym: AF0245

Alternate gene names: 11497861

Gene position: 221638-221060 (Counterclockwise)

Preceding gene: 11497862

Following gene: 11497857

Centisome position: 10.17

GC content: 49.05

Gene sequence:

>579_bases
ATGGCAGAGGAGGAAGGAAAAAGGCTTAAAGTCGATTCTGTGGAAACAGAGGCACTGGAAGAGCTGAAGAGAGAAGGATT
GCTGACAGTTGACGGAGGCATTATCAAGCTGACAGATAAAGGTAGGAAAAAGGCAGAGAAAATCGTTAGGCTTCACAGAC
TTGCTGAAAGGCTCCTTAGCGACATTTTGGGGTTTAAGGATGTTGAAGAGCACGCTTGCAAGTTCGAGCATCTAATTGAC
GATGAGGCTGAGGAGGCGATATGCACCTTACTGGGACATCCTCAGGTCTGCCCGCATGGCAGGAAAATTCCTCAGGGCCA
CTGCTGCATAGAGAAGGAAACAGAGGTGGAGAAGGTCATCTACAGGCTGAGTGAGCTCTCTCCGGGAGACGAGGCAGAAG
TCAAGTACACCGTGGCTGATGACAGGGAAACAAGGATGTTAATCTCAGCAGGCATAATTCCCGGTGTTGGGTTAAAGGTC
ATAAGGGTTTATCCCGCCTTTGTTATTCAGATTGAAAACACCCAGTTCGCCCTCGACAAGAAGCTTGCCGATGCAATTTA
CGTGGTCAGGAGGGGTTGA

Upstream 100 bases:

>100_bases
TAGCCTTTACTGCAGGCTACGCCACTGCTGTTATGATGGGGGTGGTTTGACGGTTTTAAAGCTTTCAGAAACTGCGGAGA
ACATCCTGAGAGATGTATGG

Downstream 100 bases:

>100_bases
GGTTTACATAGGTAAAAGCTCCAATAAAGCAAAAATTGTAGCCCGCCAAGTGGAATTCCCCTCACCAATCAGGGAACGCA
TGGCTGGCGGGCACGCCGGG

Product: iron-dependent repressor (desR)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAEEEGKRLKVDSVETEALEELKREGLLTVDGGIIKLTDKGRKKAEKIVRLHRLAERLLSDILGFKDVEEHACKFEHLID
DEAEEAICTLLGHPQVCPHGRKIPQGHCCIEKETEVEKVIYRLSELSPGDEAEVKYTVADDRETRMLISAGIIPGVGLKV
IRVYPAFVIQIENTQFALDKKLADAIYVVRRG

Sequences:

>Translated_192_residues
MAEEEGKRLKVDSVETEALEELKREGLLTVDGGIIKLTDKGRKKAEKIVRLHRLAERLLSDILGFKDVEEHACKFEHLID
DEAEEAICTLLGHPQVCPHGRKIPQGHCCIEKETEVEKVIYRLSELSPGDEAEVKYTVADDRETRMLISAGIIPGVGLKV
IRVYPAFVIQIENTQFALDKKLADAIYVVRRG
>Mature_191_residues
AEEEGKRLKVDSVETEALEELKREGLLTVDGGIIKLTDKGRKKAEKIVRLHRLAERLLSDILGFKDVEEHACKFEHLIDD
EAEEAICTLLGHPQVCPHGRKIPQGHCCIEKETEVEKVIYRLSELSPGDEAEVKYTVADDRETRMLISAGIIPGVGLKVI
RVYPAFVIQIENTQFALDKKLADAIYVVRRG

Specific function: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR008988
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress; PF04023 FeoA [H]

EC number: NA

Molecular weight: Translated: 21586; Mature: 21455

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEEGKRLKVDSVETEALEELKREGLLTVDGGIIKLTDKGRKKAEKIVRLHRLAERLLS
CCCCCCCEEEECCHHHHHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHH
DILGFKDVEEHACKFEHLIDDEAEEAICTLLGHPQVCPHGRKIPQGHCCIEKETEVEKVI
HHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
YRLSELSPGDEAEVKYTVADDRETRMLISAGIIPGVGLKVIRVYPAFVIQIENTQFALDK
HHHHHCCCCCCCEEEEEECCCCHHEEEEECCCCCCCCHHHHEECEEEEEEECCCHHHHHH
KLADAIYVVRRG
HHHHHHEEEECC
>Mature Secondary Structure 
AEEEGKRLKVDSVETEALEELKREGLLTVDGGIIKLTDKGRKKAEKIVRLHRLAERLLS
CCCCCCEEEECCHHHHHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHH
DILGFKDVEEHACKFEHLIDDEAEEAICTLLGHPQVCPHGRKIPQGHCCIEKETEVEKVI
HHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
YRLSELSPGDEAEVKYTVADDRETRMLISAGIIPGVGLKVIRVYPAFVIQIENTQFALDK
HHHHHCCCCCCCEEEEEECCCCHHEEEEECCCCCCCCHHHHEECEEEEEEECCCHHHHHH
KLADAIYVVRRG
HHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]