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The map label for this gene is feoB-1

Identifier: 11497862

GI number: 11497862

Start: 221689

End: 223608

Strand: Reverse

Name: feoB-1

Synonym: AF0246

Alternate gene names: 11497862

Gene position: 223608-221689 (Counterclockwise)

Preceding gene: 11497864

Following gene: 11497861

Centisome position: 10.26

GC content: 48.39

Gene sequence:

>1920_bases
ATGGAATGTCACAGTGTTAAAGCGGAAACCGTCACTGCAGAAAAAAAGGTGGCGCTCGTGGGGAACCCCAATGTGGGGAA
AAGCGCTCTATTTTACGCCCTCACCGGGAAGTATGCGACCATTTCCAACTACCCCGGCACAACAGTCGACATTGCCGTTG
CCAAACTTGGTGATCTGGAGATTATCGACACTCCGGGAATGCACTCCCTCGTTCCGGTTACGGGAGAGGAGGAGGTGGCA
AGAAAGCTGCTTGAGGAGGCTGATTTAGTCGTTCACGTTGTTGATGCGAAGAACATAAGGAGAGCGCTTCCCTTCACCCT
TCAGCTCATAGAGGCGGGGTTCAACACCATACTCGTCCTGAACCTCGTTGATGAGGCCGAGAAGTTTGGAATTTTCATAA
ACGAGAAGCTGCTTGAGGAGAGACTGGGCATTCCAGTTCTGAAAACCGTTGCGACTGAGAAGAGAGGAGTTGGGCGTCTG
AAGGATGAAATAAGAAAGAGAATTGGTTTAAAGCCAGAGAAAAAGAGGTTAATTCGCTTCTCCCCACAGGTTGAGAAAGT
TGTATCCGAGGTTGAAGGGCTGATTGAAGGAGAATACAGCATTTCAAAGAGAGGACTGGCGATTCTTCTCCTTCTGAAAG
ACTCAGTGTCACTTGAGGCCGTTAAGAGGGAGAAGAATTATCCTCAGATACTGGAAAAGGTCAGCAAAAGCAATCTTCTC
CCCTACGAGATAATGAGGGAAATCTATGAGAATGCCGAAAGAATTCTCGATGGCGTTATCGAGGAGAGGGACGTGGAGAG
CAGCATTGCAAGAAAAATCGGTATTCTCGCCCTCAATCCCCTTTTCGGAATTCCCCTAACAATTCTGTCCCTCGCCTTCA
TCTACCTTCTCGCAGGCATTCTGGGAGCTCAGATTCTCGTTGACTTAATTGAAACTTGGTTTGAGGAGAACGTTAACACT
GCCGTGAACACCTTTCTTGAGCAGAACATTCCTAATTACTGGCTGAGGGAGCTTATCGGCGGAGAGTACGGCATTATCAC
TCTCGGAATCAGATACGCAATTGCAATAATCTTCCCCATAGTCACAACCTTCTTCATTGCCTTCTCCCTTCTTGAGGATT
CGGGAATTCTTCCGAGGACGGCTTACCTGCTGGATGGAATTTTCAAGAAAATCGGGATGAGTGGCAGAGCTGTTATCCCA
CTTCTCCTCGGAACTGGATGCGGAACGATGGCCGTTATTGTTACAAGAATTCTCGAAACGTGGAGGGAGAGGGTTATTGC
CACGATTCTCCTTGCAGTGGGCATTCCATGCAGCGCTCAGCTTGGCGTGATGCTCGGAATTGCCCCTGACTTCAGGGCGA
TGATGATATGGATCTCAGTGGTTACTGCAGTTCTGCTGATAGCGGGATTTATTTCCTCAAGGGTGATTCCGGGTGAGAGA
GCAGTTTTCTTCATGGAAATACCTCCCATAAGGGTCCCAAGGCCTGAAAATGTGTTTTACAAAACCGTTTCGAGATTGGA
GTGGTACTTTAAGGAAGTTCTCCCGATTTTTGTCCTCATAAGCGTTTTGATCTGGATTGGAAGAATAACGACCGCCTTTG
ACATCATAGTTTCAGCACTGAGTGTACCAGTCTCCGCAATAGGACTTCCACCCAAAGCCTCCGAAGTGTTCCTTTACGGG
TTTTTCAGGAGGGATTACGGAGCTGCAGGACTTTTTGACATCTCCAGCGAGGGTTTGCTGAGCTACGGACAGGTTGTTGT
TGCGATGGTCACTCTAACTCTCTTTGTTCCCTGCATAGCCCAGTTCAGCATCATCTGCAAGGAGAGGGGGATAAAGCAGG
GAATAGCTGTATTCTTGCTGTCTGTGGCGATAGCCTTTACTGCAGGCTACGCCACTGCTGTTATGATGGGGGTGGTTTGA

Upstream 100 bases:

>100_bases
TAGGGCTAAGTTGTTAATAACTTTAATTTTCTGTATTAAAAAATCGGTTTTGAATTTTTTGACCAAAACCTTTAAATAAT
TTAGGTTAGCCTAAAAACCA

Downstream 100 bases:

>100_bases
CGGTTTTAAAGCTTTCAGAAACTGCGGAGAACATCCTGAGAGATGTATGGATGGCAGAGGAGGAAGGAAAAAGGCTTAAA
GTCGATTCTGTGGAAACAGA

Product: iron (II) transporter (feoB-1)

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MECHSVKAETVTAEKKVALVGNPNVGKSALFYALTGKYATISNYPGTTVDIAVAKLGDLEIIDTPGMHSLVPVTGEEEVA
RKLLEEADLVVHVVDAKNIRRALPFTLQLIEAGFNTILVLNLVDEAEKFGIFINEKLLEERLGIPVLKTVATEKRGVGRL
KDEIRKRIGLKPEKKRLIRFSPQVEKVVSEVEGLIEGEYSISKRGLAILLLLKDSVSLEAVKREKNYPQILEKVSKSNLL
PYEIMREIYENAERILDGVIEERDVESSIARKIGILALNPLFGIPLTILSLAFIYLLAGILGAQILVDLIETWFEENVNT
AVNTFLEQNIPNYWLRELIGGEYGIITLGIRYAIAIIFPIVTTFFIAFSLLEDSGILPRTAYLLDGIFKKIGMSGRAVIP
LLLGTGCGTMAVIVTRILETWRERVIATILLAVGIPCSAQLGVMLGIAPDFRAMMIWISVVTAVLLIAGFISSRVIPGER
AVFFMEIPPIRVPRPENVFYKTVSRLEWYFKEVLPIFVLISVLIWIGRITTAFDIIVSALSVPVSAIGLPPKASEVFLYG
FFRRDYGAAGLFDISSEGLLSYGQVVVAMVTLTLFVPCIAQFSIICKERGIKQGIAVFLLSVAIAFTAGYATAVMMGVV

Sequences:

>Translated_639_residues
MECHSVKAETVTAEKKVALVGNPNVGKSALFYALTGKYATISNYPGTTVDIAVAKLGDLEIIDTPGMHSLVPVTGEEEVA
RKLLEEADLVVHVVDAKNIRRALPFTLQLIEAGFNTILVLNLVDEAEKFGIFINEKLLEERLGIPVLKTVATEKRGVGRL
KDEIRKRIGLKPEKKRLIRFSPQVEKVVSEVEGLIEGEYSISKRGLAILLLLKDSVSLEAVKREKNYPQILEKVSKSNLL
PYEIMREIYENAERILDGVIEERDVESSIARKIGILALNPLFGIPLTILSLAFIYLLAGILGAQILVDLIETWFEENVNT
AVNTFLEQNIPNYWLRELIGGEYGIITLGIRYAIAIIFPIVTTFFIAFSLLEDSGILPRTAYLLDGIFKKIGMSGRAVIP
LLLGTGCGTMAVIVTRILETWRERVIATILLAVGIPCSAQLGVMLGIAPDFRAMMIWISVVTAVLLIAGFISSRVIPGER
AVFFMEIPPIRVPRPENVFYKTVSRLEWYFKEVLPIFVLISVLIWIGRITTAFDIIVSALSVPVSAIGLPPKASEVFLYG
FFRRDYGAAGLFDISSEGLLSYGQVVVAMVTLTLFVPCIAQFSIICKERGIKQGIAVFLLSVAIAFTAGYATAVMMGVV
>Mature_639_residues
MECHSVKAETVTAEKKVALVGNPNVGKSALFYALTGKYATISNYPGTTVDIAVAKLGDLEIIDTPGMHSLVPVTGEEEVA
RKLLEEADLVVHVVDAKNIRRALPFTLQLIEAGFNTILVLNLVDEAEKFGIFINEKLLEERLGIPVLKTVATEKRGVGRL
KDEIRKRIGLKPEKKRLIRFSPQVEKVVSEVEGLIEGEYSISKRGLAILLLLKDSVSLEAVKREKNYPQILEKVSKSNLL
PYEIMREIYENAERILDGVIEERDVESSIARKIGILALNPLFGIPLTILSLAFIYLLAGILGAQILVDLIETWFEENVNT
AVNTFLEQNIPNYWLRELIGGEYGIITLGIRYAIAIIFPIVTTFFIAFSLLEDSGILPRTAYLLDGIFKKIGMSGRAVIP
LLLGTGCGTMAVIVTRILETWRERVIATILLAVGIPCSAQLGVMLGIAPDFRAMMIWISVVTAVLLIAGFISSRVIPGER
AVFFMEIPPIRVPRPENVFYKTVSRLEWYFKEVLPIFVLISVLIWIGRITTAFDIIVSALSVPVSAIGLPPKASEVFLYG
FFRRDYGAAGLFDISSEGLLSYGQVVVAMVTLTLFVPCIAQFSIICKERGIKQGIAVFLLSVAIAFTAGYATAVMMGVV

Specific function: Probable GTP-driven transporter of Fe(2+) ion [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=537, Percent_Identity=26.8156424581006, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 70368; Mature: 70368

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECHSVKAETVTAEKKVALVGNPNVGKSALFYALTGKYATISNYPGTTVDIAVAKLGDLE
CCCCCCCHHHEECCCEEEEECCCCCCCHHEEEEEECCEEEECCCCCCEEEEEEECCCCEE
IIDTPGMHSLVPVTGEEEVARKLLEEADLVVHVVDAKNIRRALPFTLQLIEAGFNTILVL
EECCCCCCCEECCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEE
NLVDEAEKFGIFINEKLLEERLGIPVLKTVATEKRGVGRLKDEIRKRIGLKPEKKRLIRF
EEHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHCC
SPQVEKVVSEVEGLIEGEYSISKRGLAILLLLKDSVSLEAVKREKNYPQILEKVSKSNLL
CHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHCCCC
PYEIMREIYENAERILDGVIEERDVESSIARKIGILALNPLFGIPLTILSLAFIYLLAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHCCHHHHHHHHHHHHHHHH
LGAQILVDLIETWFEENVNTAVNTFLEQNIPNYWLRELIGGEYGIITLGIRYAIAIIFPI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
VTTFFIAFSLLEDSGILPRTAYLLDGIFKKIGMSGRAVIPLLLGTGCGTMAVIVTRILET
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHHHH
WRERVIATILLAVGIPCSAQLGVMLGIAPDFRAMMIWISVVTAVLLIAGFISSRVIPGER
HHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AVFFMEIPPIRVPRPENVFYKTVSRLEWYFKEVLPIFVLISVLIWIGRITTAFDIIVSAL
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVPVSAIGLPPKASEVFLYGFFRRDYGAAGLFDISSEGLLSYGQVVVAMVTLTLFVPCIA
HCCHHHCCCCCCCCCEEEEEEHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
QFSIICKERGIKQGIAVFLLSVAIAFTAGYATAVMMGVV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MECHSVKAETVTAEKKVALVGNPNVGKSALFYALTGKYATISNYPGTTVDIAVAKLGDLE
CCCCCCCHHHEECCCEEEEECCCCCCCHHEEEEEECCEEEECCCCCCEEEEEEECCCCEE
IIDTPGMHSLVPVTGEEEVARKLLEEADLVVHVVDAKNIRRALPFTLQLIEAGFNTILVL
EECCCCCCCEECCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEE
NLVDEAEKFGIFINEKLLEERLGIPVLKTVATEKRGVGRLKDEIRKRIGLKPEKKRLIRF
EEHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHCC
SPQVEKVVSEVEGLIEGEYSISKRGLAILLLLKDSVSLEAVKREKNYPQILEKVSKSNLL
CHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHCCCC
PYEIMREIYENAERILDGVIEERDVESSIARKIGILALNPLFGIPLTILSLAFIYLLAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHCCHHHHHHHHHHHHHHHH
LGAQILVDLIETWFEENVNTAVNTFLEQNIPNYWLRELIGGEYGIITLGIRYAIAIIFPI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
VTTFFIAFSLLEDSGILPRTAYLLDGIFKKIGMSGRAVIPLLLGTGCGTMAVIVTRILET
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHHHH
WRERVIATILLAVGIPCSAQLGVMLGIAPDFRAMMIWISVVTAVLLIAGFISSRVIPGER
HHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AVFFMEIPPIRVPRPENVFYKTVSRLEWYFKEVLPIFVLISVLIWIGRITTAFDIIVSAL
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVPVSAIGLPPKASEVFLYGFFRRDYGAAGLFDISSEGLLSYGQVVVAMVTLTLFVPCIA
HCCHHHCCCCCCCCCEEEEEEHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
QFSIICKERGIKQGIAVFLLSVAIAFTAGYATAVMMGVV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]