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The map label for this gene is trpD

Identifier: 15646202

GI number: 15646202

Start: 1355682

End: 1356689

Strand: Reverse

Name: trpD

Synonym: HP1280

Alternate gene names: 15646202

Gene position: 1356689-1355682 (Counterclockwise)

Preceding gene: 15645894

Following gene: 15645893

Centisome position: 81.34

GC content: 40.97

Gene sequence:

>1008_bases
ATGAAAGAGATTTTAAACGCTCTGTATCATCAAAAAGATTTAAACGATGAAGAAGTCAAAAAGTTATTCACCCTTATTAT
CCACGAAAAAGTAAGCCCGGTGCAACTTGGGGCCATTTTATGCGCTTTAAAAATCAAGGGCGAGAGTTTTAAGGAGATTA
GCGTTGCTGCAACCACGCTTTTAGAGCATGCCCCTAAGCCTTTTAATAGTGGCTTGGATTTAATAGACAATTGCGGCACA
GGGGGCGATGGGCTAAAAACGATCAACATCAGCACGATTGCTGCGCTCATTGCCAGCTCTATGGGATTATCTATGGCCAA
ACACGGATCAAGGAGCGTGTCCAGCCATAGCGGGAGCGCGGATTTGTTGGAAAATTTAGGCGTGAATATTGAAATGAATC
CCACGCAGTTAGAAAATTGTTTCAAACAAACGCATTTTGGGTTTTTATTCGCACCCTTATACCATCAAAGTTTTAAAAAA
TCCGCCCCTTTAAGAAAAGAGCTTTTCACTAAAACGATTTTTAATTGCTTAGGGCCTTTAATCAACCCCTTAAGGCCCAA
AATCCAGCTTTTAGGCGTGTATGACAAATCCTTGTGCAAGACCATGGCGCTAGCGTTAAAGGCTTTGGGCGTTAAAAGGG
CGATGGTGGTTAATGGAGGGGGGACGGATGAAATCGTGTTGCATGATATTACGCATGCGTGTGAATTGAAAAATAACGGA
ATTTTAGAGTATGACTTGAGCGCTAAAGATTTTGATTTGCCCCCCTATGATTTGAAAGAATTACAGATTGAAAACGCACA
AGAAAGCACTCAAGCGTGTTTAGATATTTTAGAAAATAAAGGCAAGGATTCGCATACAATGGTGGTTGTGGCGAATGTGG
CGAGTTTGTTGTATTTAAGCCATAAAGCTAAAGATTTAAAAGAGGGTGTGAGCATGACTTTAGAGCATTTAAAAACCAAA
GCGCCTTATGCGCATTTGCAAAAAATCATAAGGCTAAGCCATGCCTAG

Upstream 100 bases:

>100_bases
AAGATAAAATCTTAGCCTATCAATTCCACCCTGAAAGCATCATGACTTTACAAGGGAGGGCGTTGTTAGAGCAAAGCGTG
GGGTTTTTAGAAGGGTTATT

Downstream 100 bases:

>100_bases
CGTGTTAGAAAACATCCTTAAAGACAAGCTCCTAGAAGTCTCTGATCTTAAAAAAAACCACGCTTTACCGATAAACATAA
ACCCAAGCGATAGGGATTTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKEILNALYHQKDLNDEEVKKLFTLIIHEKVSPVQLGAILCALKIKGESFKEISVAATTLLEHAPKPFNSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYDKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDITHACELKNNG
ILEYDLSAKDFDLPPYDLKELQIENAQESTQACLDILENKGKDSHTMVVVANVASLLYLSHKAKDLKEGVSMTLEHLKTK
APYAHLQKIIRLSHA

Sequences:

>Translated_335_residues
MKEILNALYHQKDLNDEEVKKLFTLIIHEKVSPVQLGAILCALKIKGESFKEISVAATTLLEHAPKPFNSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYDKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDITHACELKNNG
ILEYDLSAKDFDLPPYDLKELQIENAQESTQACLDILENKGKDSHTMVVVANVASLLYLSHKAKDLKEGVSMTLEHLKTK
APYAHLQKIIRLSHA
>Mature_335_residues
MKEILNALYHQKDLNDEEVKKLFTLIIHEKVSPVQLGAILCALKIKGESFKEISVAATTLLEHAPKPFNSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYDKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDITHACELKNNG
ILEYDLSAKDFDLPPYDLKELQIENAQESTQACLDILENKGKDSHTMVVVANVASLLYLSHKAKDLKEGVSMTLEHLKTK
APYAHLQKIIRLSHA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=326, Percent_Identity=40.7975460122699, Blast_Score=224, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6320561, Length=337, Percent_Identity=30.2670623145401, Blast_Score=106, Evalue=5e-24,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36710; Mature: 36710

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEILNALYHQKDLNDEEVKKLFTLIIHEKVSPVQLGAILCALKIKGESFKEISVAATTL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHH
LEHAPKPFNSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSA
HHHCCCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCH
DLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPL
HHHHHCCCCEEECHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INPLRPKIQLLGVYDKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDITHACELKNNG
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEHHHHHHHHHHCCCC
ILEYDLSAKDFDLPPYDLKELQIENAQESTQACLDILENKGKDSHTMVVVANVASLLYLS
EEEEECCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
HKAKDLKEGVSMTLEHLKTKAPYAHLQKIIRLSHA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKEILNALYHQKDLNDEEVKKLFTLIIHEKVSPVQLGAILCALKIKGESFKEISVAATTL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHH
LEHAPKPFNSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSA
HHHCCCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCH
DLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPL
HHHHHCCCCEEECHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INPLRPKIQLLGVYDKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDITHACELKNNG
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEHHHHHHHHHHCCCC
ILEYDLSAKDFDLPPYDLKELQIENAQESTQACLDILENKGKDSHTMVVVANVASLLYLS
EEEEECCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
HKAKDLKEGVSMTLEHLKTKAPYAHLQKIIRLSHA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA