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Identifier: 15645476

GI number: 15645476

Start: 910338

End: 910916

Strand: Reverse

Name: Not Available

Synonym: HP0857

Alternate gene names: 15645476

Gene position: 910916-910338 (Counterclockwise)

Preceding gene: 15645477

Following gene: 15645472

Centisome position: 54.62

GC content: 39.9

Gene sequence:

>579_bases
ATGATTGATAATTTAATTAAAAAAGAATTTTTAGCCCATAAGGAAGCGTTAGAAAAAAGTTTAGAGGGTTTGCAAGAAGC
GTTAAAACAAAGCGTTCATCTTTTGATAGAAACTTTAGAAAATCAAGGGAAAATCCTTATTTGCGGTAACGGAGGGAGTG
CGAGCGATGCACAGCATTTTGCCGCTGAATTGACTGGGCGCTATAAACTAGAAAGGAAAGGTTTGAGTGCGATAAGCCTT
AATACCGATATCTCAGCCCTCACCGCCATTGCGAACGATTATGGTTATGAAGAAGTGTTTGCCAGACAAGTGGAAGCGTT
GGGGGTAAAAAACGATGTTTTGATAGGGATTTCTACAAGCGGTAATTCCAAAAATGTCCTAAAAGCTTATGAAAAAGCCA
AAGATTTAGAGATGAAAACGCTTAGTTTAGCGGGGCGTGATGGGGGGAAAATGAAGCCTTTAAGCGATATGGCTTTGATT
GTCCCTAGCGATGACACCCCACGAATCCAAGAAATGCACATTCTTATGATCCACATCTTATGCGATTGCATTGAAAGGCA
TTTCGCTCATAAAAATTAG

Upstream 100 bases:

>100_bases
GAAGTCATAGGGAGCGAGTTTGCTAAAGAAACCCATTTGATGGAGTTTGAAGAAGGTTATTCCACAAGTGCTATCATAGA
AAAAATTAAAAGGACATGCA

Downstream 100 bases:

>100_bases
CCCTAATTTTGAATTTCTTTAGGGATTTGGTAGTTTTCTATCGTTTGGATGAGTTTTTGCTTGAAAGAATCAATGTTGTT
TGGAGTGAGTAGGTATTTCT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MIDNLIKKEFLAHKEALEKSLEGLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSAISL
NTDISALTAIANDYGYEEVFARQVEALGVKNDVLIGISTSGNSKNVLKAYEKAKDLEMKTLSLAGRDGGKMKPLSDMALI
VPSDDTPRIQEMHILMIHILCDCIERHFAHKN

Sequences:

>Translated_192_residues
MIDNLIKKEFLAHKEALEKSLEGLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSAISL
NTDISALTAIANDYGYEEVFARQVEALGVKNDVLIGISTSGNSKNVLKAYEKAKDLEMKTLSLAGRDGGKMKPLSDMALI
VPSDDTPRIQEMHILMIHILCDCIERHFAHKN
>Mature_192_residues
MIDNLIKKEFLAHKEALEKSLEGLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSAISL
NTDISALTAIANDYGYEEVFARQVEALGVKNDVLIGISTSGNSKNVLKAYEKAKDLEMKTLSLAGRDGGKMKPLSDMALI
VPSDDTPRIQEMHILMIHILCDCIERHFAHKN

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=191, Percent_Identity=44.5026178010471, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI1786416, Length=189, Percent_Identity=44.973544973545, Blast_Score=159, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21103; Mature: 21103

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDNLIKKEFLAHKEALEKSLEGLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
AAELTGRYKLERKGLSAISLNTDISALTAIANDYGYEEVFARQVEALGVKNDVLIGISTS
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECC
GNSKNVLKAYEKAKDLEMKTLSLAGRDGGKMKPLSDMALIVPSDDTPRIQEMHILMIHIL
CCCHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
CDCIERHFAHKN
HHHHHHHHCCCC
>Mature Secondary Structure
MIDNLIKKEFLAHKEALEKSLEGLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
AAELTGRYKLERKGLSAISLNTDISALTAIANDYGYEEVFARQVEALGVKNDVLIGISTS
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECC
GNSKNVLKAYEKAKDLEMKTLSLAGRDGGKMKPLSDMALIVPSDDTPRIQEMHILMIHIL
CCCHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
CDCIERHFAHKN
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA