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Identifier: 15645472

GI number: 15645472

Start: 904726

End: 906327

Strand: Reverse

Name: Not Available

Synonym: HP0853

Alternate gene names: 15645472

Gene position: 906327-904726 (Counterclockwise)

Preceding gene: 15645476

Following gene: 15645471

Centisome position: 54.34

GC content: 42.2

Gene sequence:

>1602_bases
ATGCTACAAACCATCAACTTAACGCAACGCTATGCGACTAAAAAATTGTTTGAAAACGTGAATATCAAGCTGGATAAAAA
CAAACGCTACGGGCTTATTGGGGCTAATGGCGCAGGAAAGTCCACTTTTTTAAAGATTTTAAGCAAGAGCATTGATTGTA
GCAGTGGGGAAGTCATCATTACAAGCGGCATGAAAATGGGGGTTTTAGGGCAGGATCAATACGCTTTTGAAGATTTGAGC
CTTAAAGATGCGGTTTTGATAGGCAACAAGCGTTTGTATGACGCTATCAAAGAAAAAGAGCGCTTATACACCGAAGGCGA
TTTGAGCGATGATAAAGTGAATGCCAGATTAGGGGAGTTAGAAACCATTTGCGTGGAAGAAGATCCCATGTATGAATGCG
AAGTGGCGATTGAAAAAATCCTAGAAGATTTAGGCATTCCTAGCTCTAAACACAACGATTTGATGAAAACCCTGCCAAGC
AGCGATAAATTTAAAATCCTTCTCGCTCAAGTCTTGTTCCCTAAACCGGATATTTTGCTTTTAGATGAGCCGACCAACAA
CCTGGATTTAAACGCCATTGAATGGCTAGAAAACAACCTCAAACGCCATGAAGGCACGATGGTCGTCATTAGCCATGACA
GGCATTTTTTAAATGCGGTATGCACGCATATTTTGGATTTGGATTTCCACAGCGTGCGCGAATTTAGCGGGAATTATGAC
GATTGGTATATCGCTTCCACTCTGATCGCTAAACAGCAAGAGGCCGAACGCAATAAAAAACTCAAAGAAAAAGAAGAGCT
AGAAAAATTCATCGCGCGCTTTAGCGCTAACGCTTCTAAAGCCAAGCAAGCCACCAGCCGCCAAAAACAACTGGATAAAT
TAGACATTCAAAGTTTAGCGGTATCTAGCAGGAGGGATCCTAGCATTATTTTTAAACCCAAACGCACCATTGGTAATGAA
GCCTTAGAGTGCGAAAACATCTCTAAAAGTTATGACGACCAAATCGTTTTAAATCAAGTGAGCTTGAAAGTGATGCCTAA
AGACAAGATCGCCCTCATAGGGCCAAACGGCGTGGGTAAATCCACGCTTTGTAAAATTCTAGTAGAAGAATTAAAGCCGG
ATAAGGGCGTGGTGAAATGGGGGGCGACGGTTTCAAAAGGCTATTTCCCTCAAAACGTGAGCGAAGAAATTAGCGGGGAA
GAGACCTTGTATCAATGGCTCTTTAACTTCAATAAAAAGATTGAAAGCGCTGAGGTTAGGAACGCTTTAGGGAGGATGCT
GTTTAATGGCGAAGAGCAAGAAAAATGCGTGAACGCTTTAAGTGGGGGCGAAAAACACCGAATGGTTTTATCCAAGCTCA
TGCTAGAGGGGGGGAATTTTTTAGTCTTAGATGAGCCAACCAACCATTTGGATTTAGAAGCGATTATCGCTTTAGGCGAA
GCGCTCTTTAAATTTGATGGGGCGCTGATTTGCGTAAGCCATGACAGAGAGCTCATTGATGCGTATGCTAATAGGATCAT
TGAATTAGTCCCAAGCCCTAAAGGCGCTTCAATCATTGATTTTAAAGGCAGTTATGAAGAGTATTTGGCGAGCAAAAAAT
GA

Upstream 100 bases:

>100_bases
AAAGACCTTACAGATAACCATAATAAGCAAGGGTTACAATATTGCAAAGAAAACGCTACAATAAACTTTCTCTAATCACA
AAAAATAAGGAAATCATAAG

Downstream 100 bases:

>100_bases
AACCGCAAGACATTGAAATCGTTCAAAGCGTTTTAGAGATTACAGGACCGATTAAGCCTACTGAAGTGTATGATAAAGCC
AAAGAGCTTTTTGAAAAAGG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMKMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYTEGDLSDDKVNARLGELETICVEEDPMYECEVAIEKILEDLGIPSSKHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDDQIVLNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGALICVSHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKK

Sequences:

>Translated_533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMKMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYTEGDLSDDKVNARLGELETICVEEDPMYECEVAIEKILEDLGIPSSKHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDDQIVLNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGALICVSHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKK
>Mature_533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMKMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYTEGDLSDDKVNARLGELETICVEEDPMYECEVAIEKILEDLGIPSSKHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDDQIVLNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGALICVSHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI10947137, Length=541, Percent_Identity=31.6081330868762, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI27881506, Length=541, Percent_Identity=31.6081330868762, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI148612853, Length=539, Percent_Identity=30.0556586270872, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI69354671, Length=535, Percent_Identity=30.6542056074766, Blast_Score=192, Evalue=9e-49,
Organism=Homo sapiens, GI10947135, Length=535, Percent_Identity=30.6542056074766, Blast_Score=191, Evalue=1e-48,
Organism=Escherichia coli, GI1787041, Length=533, Percent_Identity=42.9643527204503, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1789751, Length=530, Percent_Identity=32.4528301886792, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI2367384, Length=537, Percent_Identity=32.5884543761639, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1787182, Length=551, Percent_Identity=29.7640653357532, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1788165, Length=193, Percent_Identity=32.6424870466321, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788897, Length=505, Percent_Identity=21.1881188118812, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790739, Length=210, Percent_Identity=28.0952380952381, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788225, Length=222, Percent_Identity=24.3243243243243, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789891, Length=204, Percent_Identity=26.4705882352941, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=526, Percent_Identity=31.9391634980989, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17555318, Length=515, Percent_Identity=30.0970873786408, Blast_Score=228, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17559834, Length=514, Percent_Identity=30.7392996108949, Blast_Score=220, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320874, Length=505, Percent_Identity=34.0594059405941, Blast_Score=236, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6321121, Length=538, Percent_Identity=30.8550185873606, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6325030, Length=406, Percent_Identity=26.6009852216749, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=427, Percent_Identity=25.5269320843091, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323278, Length=421, Percent_Identity=24.2280285035629, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24642252, Length=540, Percent_Identity=29.8148148148148, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI18859989, Length=540, Percent_Identity=29.8148148148148, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24666836, Length=506, Percent_Identity=32.6086956521739, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24641342, Length=524, Percent_Identity=29.7709923664122, Blast_Score=216, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59932; Mature: 59932

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVII
CCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEE
TSGMKMGVLGQDQYAFEDLSLKDAVLIGNKRLYDAIKEKERLYTEGDLSDDKVNARLGEL
ECCCEECCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCE
ETICVEEDPMYECEVAIEKILEDLGIPSSKHNDLMKTLPSSDKFKILLAQVLFPKPDILL
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCEEE
LDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHCCCCC
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLA
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VSSRRDPSIIFKPKRTIGNEALECENISKSYDDQIVLNQVSLKVMPKDKIALIGPNGVGK
HCCCCCCCEEECCCHHCCCCHHHHHHCCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCH
STLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGEETLYQWLFNFNKKIESAEVR
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
NALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
ALFKFDGALICVSHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKK
HHHHCCCEEEEEECCHHHHHHHHHHHEEECCCCCCCEEEECCCCHHHHHCCCC
>Mature Secondary Structure
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVII
CCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEE
TSGMKMGVLGQDQYAFEDLSLKDAVLIGNKRLYDAIKEKERLYTEGDLSDDKVNARLGEL
ECCCEECCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCE
ETICVEEDPMYECEVAIEKILEDLGIPSSKHNDLMKTLPSSDKFKILLAQVLFPKPDILL
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCEEE
LDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHCCCCC
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLA
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VSSRRDPSIIFKPKRTIGNEALECENISKSYDDQIVLNQVSLKVMPKDKIALIGPNGVGK
HCCCCCCCEEECCCHHCCCCHHHHHHCCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCH
STLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGEETLYQWLFNFNKKIESAEVR
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
NALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
ALFKFDGALICVSHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKK
HHHHCCCEEEEEECCHHHHHHHHHHHEEECCCCCCCEEEECCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]