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The map label for this gene is deoD

Identifier: 13507801

GI number: 13507801

Start: 79033

End: 79749

Strand: Direct

Name: deoD

Synonym: MPN062

Alternate gene names: 13507801

Gene position: 79033-79749 (Clockwise)

Preceding gene: 13507799

Following gene: 13507802

Centisome position: 9.68

GC content: 46.58

Gene sequence:

>717_bases
ATGACACCGCACATAAACGCAAAAAAAGATGACATTGCTAAGGTTGTTTTAATGCCCGGTGATCCCTTACGTGCTAAGTG
GATTGCGGAACAATTTATGGAAAAGCCCCGGCTCGTCAACGAAGTGCGAGGCATGTTAGCTTTTACCGGTCAGTATAAGG
GTAAAACCATTACCATTATGGGCCATGGCATGGGGATTCCCTCAATTGGGATTTATTCTTATGAACTGATGAAGTTCTAT
GAGGTTAATACCATTATCCGAATTGGTAGTTGCGGGGCGTTGCAAGGTTCCTTAAACCTCCAGGACCTCATTATTGCCGC
TAAGGCTTGGAGTGAGTCGATTTACGCTAACGACATGGGTGTGGAAGTGCCAGCAGACAAGATCTTAATGGCCTCCCCGC
AACTAGTAGAGTTAGCTAAAAAGACCGCTAACCAACTTCAACTGGCCTTCCATGAGGGCTTGGTGTTCTGTGAGGATGCC
TTCCACCAAATCAGGAAAGACGTGTTAAAGCTAGCACAAGAAAAACACGCTTTAGCAGTGGAAATGGAAGCGCATGCTCT
GTACGCTAATGCCATGCTGCTCAACAAGCAAGCGTTAACGATGCTCACGGTGTCCGATTCTTTGGTAACCCATGCTGCTC
TACCAGCGGAACAACGCCAAGCCACCTTTAAGAACATGGCTATCTTATCCTTGGAAATGGCTAGCCAACTCGTTTAA

Upstream 100 bases:

>100_bases
TTGCATCGAGCGCATAACGATGCTCGAGATCATTGACTTAAACATGGTGCTTTAATTATTTATTTTTTTATTATTTCTAC
GTATAGATAAAGCTAGTTTC

Downstream 100 bases:

>100_bases
ACAATGAAATTAGAATACAACCGCATTATTGACAGTACACTACTTAAAGCTGATACCTTACCCCACGAAATTGATGCTTT
ATGTGCTGATGCTCATAAGT

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTPHINAKKDDIAKVVLMPGDPLRAKWIAEQFMEKPRLVNEVRGMLAFTGQYKGKTITIMGHGMGIPSIGIYSYELMKFY
EVNTIIRIGSCGALQGSLNLQDLIIAAKAWSESIYANDMGVEVPADKILMASPQLVELAKKTANQLQLAFHEGLVFCEDA
FHQIRKDVLKLAQEKHALAVEMEAHALYANAMLLNKQALTMLTVSDSLVTHAALPAEQRQATFKNMAILSLEMASQLV

Sequences:

>Translated_238_residues
MTPHINAKKDDIAKVVLMPGDPLRAKWIAEQFMEKPRLVNEVRGMLAFTGQYKGKTITIMGHGMGIPSIGIYSYELMKFY
EVNTIIRIGSCGALQGSLNLQDLIIAAKAWSESIYANDMGVEVPADKILMASPQLVELAKKTANQLQLAFHEGLVFCEDA
FHQIRKDVLKLAQEKHALAVEMEAHALYANAMLLNKQALTMLTVSDSLVTHAALPAEQRQATFKNMAILSLEMASQLV
>Mature_237_residues
TPHINAKKDDIAKVVLMPGDPLRAKWIAEQFMEKPRLVNEVRGMLAFTGQYKGKTITIMGHGMGIPSIGIYSYELMKFYE
VNTIIRIGSCGALQGSLNLQDLIIAAKAWSESIYANDMGVEVPADKILMASPQLVELAKKTANQLQLAFHEGLVFCEDAF
HQIRKDVLKLAQEKHALAVEMEAHALYANAMLLNKQALTMLTVSDSLVTHAALPAEQRQATFKNMAILSLEMASQLV

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=231, Percent_Identity=44.5887445887446, Blast_Score=191, Evalue=3e-50,
Organism=Escherichia coli, GI1790265, Length=170, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_MYCPN (P75053)

Other databases:

- EMBL:   U00089
- PIR:   S73418
- RefSeq:   NP_109750.1
- ProteinModelPortal:   P75053
- SMR:   P75053
- IntAct:   P75053
- GeneID:   876955
- GenomeReviews:   U00089_GR
- KEGG:   mpn:MPN062
- HOGENOM:   HBG617197
- OMA:   HEIAREK
- ProtClustDB:   PRK05819
- BioCyc:   MetaCyc:MONOMER-561
- BioCyc:   MPNE272634:MPN062-MONOMER
- BRENDA:   2.4.2.1
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 26284; Mature: 26153

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHINAKKDDIAKVVLMPGDPLRAKWIAEQFMEKPRLVNEVRGMLAFTGQYKGKTITIM
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCEEEEE
GHGMGIPSIGIYSYELMKFYEVNTIIRIGSCGALQGSLNLQDLIIAAKAWSESIYANDMG
ECCCCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHEEHHHHCCHHEECCCC
VEVPADKILMASPQLVELAKKTANQLQLAFHEGLVFCEDAFHQIRKDVLKLAQEKHALAV
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCCEEE
EMEAHALYANAMLLNKQALTMLTVSDSLVTHAALPAEQRQATFKNMAILSLEMASQLV
EEHHHHHHHHHHEECCCCEEEEEECHHHHHHHCCCHHHHHHHHHHHHHEEHHHHHHCC
>Mature Secondary Structure 
TPHINAKKDDIAKVVLMPGDPLRAKWIAEQFMEKPRLVNEVRGMLAFTGQYKGKTITIM
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCEEEEE
GHGMGIPSIGIYSYELMKFYEVNTIIRIGSCGALQGSLNLQDLIIAAKAWSESIYANDMG
ECCCCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHEEHHHHCCHHEECCCC
VEVPADKILMASPQLVELAKKTANQLQLAFHEGLVFCEDAFHQIRKDVLKLAQEKHALAV
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCCEEE
EMEAHALYANAMLLNKQALTMLTVSDSLVTHAALPAEQRQATFKNMAILSLEMASQLV
EEHHHHHHHHHHEECCCCEEEEEECHHHHHHHCCCHHHHHHHHHHHHHEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633