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The map label for this gene is hmvA

Identifier: 15669843

GI number: 15669843

Start: 1629137

End: 1629427

Strand: Direct

Name: hmvA

Synonym: MJ1647

Alternate gene names: 15669843

Gene position: 1629137-1629427 (Clockwise)

Preceding gene: 15669842

Following gene: 15669844

Centisome position: 97.85

GC content: 31.62

Gene sequence:

>291_bases
ATGTTACCAAAAGCTACAGTAAAGAGGATTATGAAACAACACACAGACTTTAACATCTCTGCAGAGGCGGTTGATGAACT
CTGTAATATGCTTGAAGAAATTATAAAGATAACAACTGAAGTTGCAGAGCAAAATGCAAGAAAGGAAGGGAGAAAAACAA
TTAAAGCAAGAGATATTAAACAGTGTGATGATGAAAGATTAAAGAGAAAGATTATGGAACTTAGTGAAAGAACTGATAAG
ATGCCAATATTAATTAAAGAGATGTTGAATGTAATAACATCTGAATTATAG

Upstream 100 bases:

>100_bases
TTAGAATAGGGGCTGTAAATGTAGAGCAAAAATAAAATAAACATTTTATTATCTTTATTTTTATTATTTTTATTTCAAAA
ATTTTTGGAGGTATATATTT

Downstream 100 bases:

>100_bases
TTCTTTTCAAAAGTGAATAAAATTTATTAAGGAAGTTTGAACTCCTTCCATTAGGAAGGAGTTCATCAGTGCCTTAGTTA
TTACAAAATATTTTGAAAAG

Product: DNA binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MLPKATVKRIMKQHTDFNISAEAVDELCNMLEEIIKITTEVAEQNARKEGRKTIKARDIKQCDDERLKRKIMELSERTDK
MPILIKEMLNVITSEL

Sequences:

>Translated_96_residues
MLPKATVKRIMKQHTDFNISAEAVDELCNMLEEIIKITTEVAEQNARKEGRKTIKARDIKQCDDERLKRKIMELSERTDK
MPILIKEMLNVITSEL
>Mature_96_residues
MLPKATVKRIMKQHTDFNISAEAVDELCNMLEEIIKITTEVAEQNARKEGRKTIKARDIKQCDDERLKRKIMELSERTDK
MPILIKEMLNVITSEL

Specific function: Binds and compacts DNA to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation

COG id: COG2036

COG function: function code B; Histones H3 and H4

Gene ontology:

Cell location: Cytoplasm (Potential). Chromosome (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal histone HMF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HMVA_METJA (Q59041)

Other databases:

- EMBL:   L77117
- PIR:   E64505
- RefSeq:   NP_248657.1
- ProteinModelPortal:   Q59041
- SMR:   Q59041
- GeneID:   1452556
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1647
- NMPDR:   fig|243232.1.peg.1694
- TIGR:   MJ1647
- HOGENOM:   HBG541196
- OMA:   TVKRIMK
- ProtClustDB:   CLSK876656
- BioCyc:   MJAN243232:MJ_1647-MONOMER
- GO:   GO:0005694
- GO:   GO:0005737
- InterPro:   IPR003958
- InterPro:   IPR009072
- Gene3D:   G3DSA:1.10.20.10

Pfam domain/function: PF00808 CBFD_NFYB_HMF; SSF47113 Histone-fold

EC number: NA

Molecular weight: Translated: 11201; Mature: 11201

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKATVKRIMKQHTDFNISAEAVDELCNMLEEIIKITTEVAEQNARKEGRKTIKARDIK
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QCDDERLKRKIMELSERTDKMPILIKEMLNVITSEL
HCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPKATVKRIMKQHTDFNISAEAVDELCNMLEEIIKITTEVAEQNARKEGRKTIKARDIK
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QCDDERLKRKIMELSERTDKMPILIKEMLNVITSEL
HCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 10741836