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The map label for this gene is mtrD

Identifier: 15669038

GI number: 15669038

Start: 774628

End: 775320

Strand: Direct

Name: mtrD

Synonym: MJ0848

Alternate gene names: 15669038

Gene position: 774628-775320 (Clockwise)

Preceding gene: 15669037

Following gene: 15669039

Centisome position: 46.53

GC content: 39.97

Gene sequence:

>693_bases
ATGGATATTGTTAGCGCAATTGTTCCATTAATTGAGATGACTATTGCAGGGGCAATAATTAATGCAAGTGTTCATTTTAT
CCCTGTTGGAGGGGCTCCAGCGGCTATGGCGACCTCAACAGGGGTTGGAACAGGAACAACACAGTTGGCAGCAGGGGCAG
GTTTTACTGGATTGATGGGTGCTGCAGTAATGGCATCAAATGTAGGTTTATCACCTATTGGAATGGCATTGATTATGATC
TCTGGAGCTGTAAGTTCAATGATTATGCTCGGAGTAACGATGTTAATTGGGCAATTAATTTATGTATTTGGAGTTGGGGT
TGTTCCAGCTGCAGATAAGTGTGAAATTGATCCTATAACTAAAGATCCACAAAAACCTTATGTTACTCCAGGGACTACAG
GACATGGAGTTCCAACTGTTTGTTTTGTTAGTGGTTTAATAGGAGCGGCTTTAGGAGGAATTGGTGGAGCTTTAGCATAC
ATTGCTTTAAGAAAACTCGGTTTAGATCCAGGAGTTGCAGGGATGTTAGCAGTTGGTTTCTTCTTTATCAATGCGGTTTT
AGCATCATATAACATTGGAGGGACTATTGAAGGATTCCACGACCCAAAATTCAAGAAAATGCCTAATGGAGTTATTGCAT
CAACAGTAGCTTCATTATTGTTTGGTATAATTTCAGTATTGATGGTTTTATAA

Upstream 100 bases:

>100_bases
GGTTTGATAATCGTAGCTATATTGGCAATAATAAATAGAAAGGTTGAGGTCTTTGCAAGAAATAAGTATGGACCATACAC
AAAATAAAAGGTGATAATGT

Downstream 100 bases:

>100_bases
ATTTAACAATATAGAATGGGTGATTAATTATGTCACATGGTGGAGGAGGTCATGCAGCTGAACTTTATCCTGAAGAGCAA
ATATTTGCTGTAGGTATTGC

Product: tetrahydromethanopterin S-methyltransferase subunit D

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MDIVSAIVPLIEMTIAGAIINASVHFIPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLMGAAVMASNVGLSPIGMALIMI
SGAVSSMIMLGVTMLIGQLIYVFGVGVVPAADKCEIDPITKDPQKPYVTPGTTGHGVPTVCFVSGLIGAALGGIGGALAY
IALRKLGLDPGVAGMLAVGFFFINAVLASYNIGGTIEGFHDPKFKKMPNGVIASTVASLLFGIISVLMVL

Sequences:

>Translated_230_residues
MDIVSAIVPLIEMTIAGAIINASVHFIPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLMGAAVMASNVGLSPIGMALIMI
SGAVSSMIMLGVTMLIGQLIYVFGVGVVPAADKCEIDPITKDPQKPYVTPGTTGHGVPTVCFVSGLIGAALGGIGGALAY
IALRKLGLDPGVAGMLAVGFFFINAVLASYNIGGTIEGFHDPKFKKMPNGVIASTVASLLFGIISVLMVL
>Mature_230_residues
MDIVSAIVPLIEMTIAGAIINASVHFIPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLMGAAVMASNVGLSPIGMALIMI
SGAVSSMIMLGVTMLIGQLIYVFGVGVVPAADKCEIDPITKDPQKPYVTPGTTGHGVPTVCFVSGLIGAALGGIGGALAY
IALRKLGLDPGVAGMLAVGFFFINAVLASYNIGGTIEGFHDPKFKKMPNGVIASTVASLLFGIISVLMVL

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4060

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit D

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRD_METJA (Q58258)

Other databases:

- EMBL:   L77117
- PIR:   H64405
- RefSeq:   NP_247842.1
- ProteinModelPortal:   Q58258
- GeneID:   1451736
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0848
- NMPDR:   fig|243232.1.peg.879
- TIGR:   MJ0848
- HOGENOM:   HBG551221
- OMA:   HFVPVGG
- ProtClustDB:   PRK00968
- BioCyc:   MJAN243232:MJ_0848-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0005737
- GO:   GO:0015948
- HAMAP:   MF_01097
- InterPro:   IPR005779
- PIRSF:   PIRSF016552
- ProDom:   PD013594
- TIGRFAMs:   TIGR01112

Pfam domain/function: PF04207 MtrD

EC number: =2.1.1.86

Molecular weight: Translated: 22880; Mature: 22880

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdabff90)-; HASH(0xd1bedf4)-; HASH(0xc76882c)-; HASH(0xd8dc1c8)-; HASH(0xd4c60d0)-; HASH(0x406bd9a8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVSAIVPLIEMTIAGAIINASVHFIPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLMG
CCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCCCCCCHHHHHHCCCHHHHHH
AAVMASNVGLSPIGMALIMISGAVSSMIMLGVTMLIGQLIYVFGVGVVPAADKCEIDPIT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
KDPQKPYVTPGTTGHGVPTVCFVSGLIGAALGGIGGALAYIALRKLGLDPGVAGMLAVGF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FFINAVLASYNIGGTIEGFHDPKFKKMPNGVIASTVASLLFGIISVLMVL
HHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MDIVSAIVPLIEMTIAGAIINASVHFIPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLMG
CCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCCCCCCHHHHHHCCCHHHHHH
AAVMASNVGLSPIGMALIMISGAVSSMIMLGVTMLIGQLIYVFGVGVVPAADKCEIDPIT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
KDPQKPYVTPGTTGHGVPTVCFVSGLIGAALGGIGGALAYIALRKLGLDPGVAGMLAVGF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FFINAVLASYNIGGTIEGFHDPKFKKMPNGVIASTVASLLFGIISVLMVL
HHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087