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The map label for this gene is mtrC

Identifier: 15669039

GI number: 15669039

Start: 775350

End: 776147

Strand: Direct

Name: mtrC

Synonym: MJ0849

Alternate gene names: 15669039

Gene position: 775350-776147 (Clockwise)

Preceding gene: 15669038

Following gene: 15669040

Centisome position: 46.57

GC content: 36.59

Gene sequence:

>798_bases
ATGTCACATGGTGGAGGAGGTCATGCAGCTGAACTTTATCCTGAAGAGCAAATATTTGCTGTAGGTATTGCTTTATCATT
GGTTGGATGCTATTTAGCAAACTTTTTGTCACCTTATGGATTGGGAATGTTAATTGGCGGTTTATTGGCATCTGCAGCAT
GTGTTGCTGGAGCAAATACTGTTAGGAAAGTAGCTGCTTACGGTCTTGGAACAGGAGTTCCGTCCATTGGTATGGTAAGT
TTAGGTATGGGAACATTGGCGGCAGTTGCAGGTGTTTTAATTCCTGATTACTTCAATCTTCCTTATTTGGTAGCTCCAAT
TATAACATTGATAGTTTCAGCAGTTATTGGATATATCGTTGGAAGATTAACAGTAAATCCAGTAGGTATGAAGATTCCAA
TTATGGTTAGAAGTATGACATTTTTATCAATTGCAGGAGCCATGGCTTTATTAGGATTTACTGTTGCCTATGTGGGTAGT
TTAGAACCACAAAAATACATTGATTATGCATTAAATAATGGTATGATGGCCTTGGCATTTATTGCTGCGGGTATGGCAAT
ATTACATCCATTTAACGCATGTTTGGGTCCAAATGAAAGCCATAAGAGAACATTAACATTAGCAGTTGCTTGTGGTTTTA
TAACATGGTTTGTATTCTCAGTAGTTAAATTAGATATAGTATCTATAATTGTTTCAATAATATTATGGGCAATTGTCTAT
GTGAAGTTTGTTAAGATGTCATTTAAAGATGCCTGTGCAGTTCTTCACGTTCCAGAGATTCCTAAGAAGGAGGAATAA

Upstream 100 bases:

>100_bases
CTAATGGAGTTATTGCATCAACAGTAGCTTCATTATTGTTTGGTATAATTTCAGTATTGATGGTTTTATAAATTTAACAA
TATAGAATGGGTGATTAATT

Downstream 100 bases:

>100_bases
GGTGATAATATGGCAACTTATGTATTTATAGACCAGAATATTCCTTTAGTATATACTGTTGAAACAGGAGTAATTACAAA
AGGATTTGGAGATTTGTTAT

Product: tetrahydromethanopterin S-methyltransferase subunit C

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSHGGGGHAAELYPEEQIFAVGIALSLVGCYLANFLSPYGLGMLIGGLLASAACVAGANTVRKVAAYGLGTGVPSIGMVS
LGMGTLAAVAGVLIPDYFNLPYLVAPIITLIVSAVIGYIVGRLTVNPVGMKIPIMVRSMTFLSIAGAMALLGFTVAYVGS
LEPQKYIDYALNNGMMALAFIAAGMAILHPFNACLGPNESHKRTLTLAVACGFITWFVFSVVKLDIVSIIVSIILWAIVY
VKFVKMSFKDACAVLHVPEIPKKEE

Sequences:

>Translated_265_residues
MSHGGGGHAAELYPEEQIFAVGIALSLVGCYLANFLSPYGLGMLIGGLLASAACVAGANTVRKVAAYGLGTGVPSIGMVS
LGMGTLAAVAGVLIPDYFNLPYLVAPIITLIVSAVIGYIVGRLTVNPVGMKIPIMVRSMTFLSIAGAMALLGFTVAYVGS
LEPQKYIDYALNNGMMALAFIAAGMAILHPFNACLGPNESHKRTLTLAVACGFITWFVFSVVKLDIVSIIVSIILWAIVY
VKFVKMSFKDACAVLHVPEIPKKEE
>Mature_264_residues
SHGGGGHAAELYPEEQIFAVGIALSLVGCYLANFLSPYGLGMLIGGLLASAACVAGANTVRKVAAYGLGTGVPSIGMVSL
GMGTLAAVAGVLIPDYFNLPYLVAPIITLIVSAVIGYIVGRLTVNPVGMKIPIMVRSMTFLSIAGAMALLGFTVAYVGSL
EPQKYIDYALNNGMMALAFIAAGMAILHPFNACLGPNESHKRTLTLAVACGFITWFVFSVVKLDIVSIIVSIILWAIVYV
KFVKMSFKDACAVLHVPEIPKKEE

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4061

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit C

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRC_METJA (Q58259)

Other databases:

- EMBL:   L77117
- PIR:   A64406
- RefSeq:   NP_247843.1
- ProteinModelPortal:   Q58259
- GeneID:   1451737
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0849
- NMPDR:   fig|243232.1.peg.880
- TIGR:   MJ0849
- HOGENOM:   HBG542041
- OMA:   ILHPFNA
- ProtClustDB:   PRK01030
- BioCyc:   MJAN243232:MJ_0849-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0015948
- HAMAP:   MF_01096
- InterPro:   IPR005865
- PIRSF:   PIRSF006530
- ProDom:   PD013899
- TIGRFAMs:   TIGR01148

Pfam domain/function: PF04211 MtrC

EC number: =2.1.1.86

Molecular weight: Translated: 27805; Mature: 27674

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcf12e74)-; HASH(0xd4ff3e4)-; HASH(0xd9b2920)-; HASH(0xc3b2548)-; HASH(0xd9ac4ec)-; HASH(0xcfa25e8)-; HASH(0xd9af598)-; HASH(0xd9af928)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHEEECCCCCCCCH
>Mature Secondary Structure 
SHGGGGHAAELYPEEQIFAVGIALSLVGCYLANFLSPYGLGMLIGGLLASAACVAGANT
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VRKVAAYGLGTGVPSIGMVSLGMGTLAAVAGVLIPDYFNLPYLVAPIITLIVSAVIGYIV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GRLTVNPVGMKIPIMVRSMTFLSIAGAMALLGFTVAYVGSLEPQKYIDYALNNGMMALAF
HHHEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHH
IAAGMAILHPFNACLGPNESHKRTLTLAVACGFITWFVFSVVKLDIVSIIVSIILWAIVY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKFVKMSFKDACAVLHVPEIPKKEE
HHHHHHHHHHHHHEEECCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087