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The map label for this gene is mtrE

Identifier: 15669037

GI number: 15669037

Start: 773703

End: 774614

Strand: Direct

Name: mtrE

Synonym: MJ0847

Alternate gene names: 15669037

Gene position: 773703-774614 (Clockwise)

Preceding gene: 15669036

Following gene: 15669038

Centisome position: 46.47

GC content: 38.49

Gene sequence:

>912_bases
ATGGATGCAACACTGATAGCCCTTGGGGCTTTAGCGTTGAGTGGTGCATTGGCAACAGTTGCTGGATGTGCAGAAGATTT
GGAATCTGATGTAGGGTCTCAGTCAAACCCAAACTCACAGGTTCAGTTAGCTCCACAGATGGGGAATATACACAGATACT
TTAACAAGGCTATATCTGGGGAGCCAGTTTCTTATGGTTTGTATGTTGCAGTTGCGGGGACAGTTGCTTATGCTATTATG
CAAATGGGATTAAACCCAATTTTAGCGTTAATTTTAGGAGCAGGAGTAGCTGCTTTTGTTCATGGGGCTTATGCTATTTC
AGCATATTTAGGTAGAATTGTGGGTCAATCAAAGAACTTTGGTCAGCCAGTTTATTGGGATGTTGTAATGAGCCATCTTG
GCCCAATTGTTGGACATGGTTTTATTGCAGTCTTTTGTATGGTTTTAATGGCTTATTTAGCTAACACTATATTAGGAAAC
CCATTCCCACTGCCATTGATTGCATTGATATTTGGGATTACTGTTGGTGCAATTGGTTCATCAACTGGAGACGTTCATTA
TGGTGCTGAAAGAGAATATCAAAAATATCCATTTGGAGGAGGAGTTCCAGTTGCTAACCATGGAGATATTGACATTAAAG
CAGAATATGGTTTAAGAAACGGTATGGACTCCTCATACTTCTGTTCAAGATTAGGAGGAGTTTTAACTGGTTTATGCTTT
GGTTTAATTGTATTTTTAGATGGTTGGAGAGGTGTTTTGGGAGATATATTAAAAGGAGGTCAGGGAGGAAGTGTAATAAC
TGCTTCAATAATATCAATTGTTATTGGTTTGATAATCGTAGCTATATTGGCAATAATAAATAGAAAGGTTGAGGTCTTTG
CAAGAAATAAGTATGGACCATACACAAAATAA

Upstream 100 bases:

>100_bases
AAAAGTTAAATAAAAATTAAGTGAATTTTAACAGAATCAAATAGAAAACCTTATATATTAACCTAATAAAACTAAGTCTT
ATGTAAAATGAGGTGATAGG

Downstream 100 bases:

>100_bases
AAGGTGATAATGTATGGATATTGTTAGCGCAATTGTTCCATTAATTGAGATGACTATTGCAGGGGCAATAATTAATGCAA
GTGTTCATTTTATCCCTGTT

Product: tetrahydromethanopterin S-methyltransferase subunit E

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDATLIALGALALSGALATVAGCAEDLESDVGSQSNPNSQVQLAPQMGNIHRYFNKAISGEPVSYGLYVAVAGTVAYAIM
QMGLNPILALILGAGVAAFVHGAYAISAYLGRIVGQSKNFGQPVYWDVVMSHLGPIVGHGFIAVFCMVLMAYLANTILGN
PFPLPLIALIFGITVGAIGSSTGDVHYGAEREYQKYPFGGGVPVANHGDIDIKAEYGLRNGMDSSYFCSRLGGVLTGLCF
GLIVFLDGWRGVLGDILKGGQGGSVITASIISIVIGLIIVAILAIINRKVEVFARNKYGPYTK

Sequences:

>Translated_303_residues
MDATLIALGALALSGALATVAGCAEDLESDVGSQSNPNSQVQLAPQMGNIHRYFNKAISGEPVSYGLYVAVAGTVAYAIM
QMGLNPILALILGAGVAAFVHGAYAISAYLGRIVGQSKNFGQPVYWDVVMSHLGPIVGHGFIAVFCMVLMAYLANTILGN
PFPLPLIALIFGITVGAIGSSTGDVHYGAEREYQKYPFGGGVPVANHGDIDIKAEYGLRNGMDSSYFCSRLGGVLTGLCF
GLIVFLDGWRGVLGDILKGGQGGSVITASIISIVIGLIIVAILAIINRKVEVFARNKYGPYTK
>Mature_303_residues
MDATLIALGALALSGALATVAGCAEDLESDVGSQSNPNSQVQLAPQMGNIHRYFNKAISGEPVSYGLYVAVAGTVAYAIM
QMGLNPILALILGAGVAAFVHGAYAISAYLGRIVGQSKNFGQPVYWDVVMSHLGPIVGHGFIAVFCMVLMAYLANTILGN
PFPLPLIALIFGITVGAIGSSTGDVHYGAEREYQKYPFGGGVPVANHGDIDIKAEYGLRNGMDSSYFCSRLGGVLTGLCF
GLIVFLDGWRGVLGDILKGGQGGSVITASIISIVIGLIIVAILAIINRKVEVFARNKYGPYTK

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4059

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit E

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRE_METJA (Q58257)

Other databases:

- EMBL:   L77117
- PIR:   G64405
- RefSeq:   NP_247841.1
- ProteinModelPortal:   Q58257
- GeneID:   1451735
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0847
- NMPDR:   fig|243232.1.peg.878
- TIGR:   MJ0847
- HOGENOM:   HBG539646
- OMA:   SNPNSQV
- ProtClustDB:   PRK00972
- BioCyc:   MJAN243232:MJ_0847-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0005737
- GO:   GO:0015948
- HAMAP:   MF_01098
- InterPro:   IPR005780
- PIRSF:   PIRSF016509
- TIGRFAMs:   TIGR01113

Pfam domain/function: PF04206 MtrE

EC number: =2.1.1.86

Molecular weight: Translated: 31635; Mature: 31635

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd2993a4)-; HASH(0xd5e0d98)-; HASH(0xd54c9ac)-; HASH(0xc645d90)-; HASH(0xd4cb528)-; HASH(0xda93690)-; HASH(0xda9b884)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATLIALGALALSGALATVAGCAEDLESDVGSQSNPNSQVQLAPQMGNIHRYFNKAISG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHCCC
EPVSYGLYVAVAGTVAYAIMQMGLNPILALILGAGVAAFVHGAYAISAYLGRIVGQSKNF
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GQPVYWDVVMSHLGPIVGHGFIAVFCMVLMAYLANTILGNPFPLPLIALIFGITVGAIGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
STGDVHYGAEREYQKYPFGGGVPVANHGDIDIKAEYGLRNGMDSSYFCSRLGGVLTGLCF
CCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
GLIVFLDGWRGVLGDILKGGQGGSVITASIISIVIGLIIVAILAIINRKVEVFARNKYGP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCC
YTK
CCH
>Mature Secondary Structure
MDATLIALGALALSGALATVAGCAEDLESDVGSQSNPNSQVQLAPQMGNIHRYFNKAISG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHCCC
EPVSYGLYVAVAGTVAYAIMQMGLNPILALILGAGVAAFVHGAYAISAYLGRIVGQSKNF
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GQPVYWDVVMSHLGPIVGHGFIAVFCMVLMAYLANTILGNPFPLPLIALIFGITVGAIGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
STGDVHYGAEREYQKYPFGGGVPVANHGDIDIKAEYGLRNGMDSSYFCSRLGGVLTGLCF
CCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
GLIVFLDGWRGVLGDILKGGQGGSVITASIISIVIGLIIVAILAIINRKVEVFARNKYGP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCC
YTK
CCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087