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The map label for this gene is slyD [C]

Identifier: 15668453

GI number: 15668453

Start: 264807

End: 265280

Strand: Reverse

Name: slyD [C]

Synonym: MJ0278

Alternate gene names: 15668453

Gene position: 265280-264807 (Counterclockwise)

Preceding gene: 15668456

Following gene: 15668452

Centisome position: 15.93

GC content: 33.12

Gene sequence:

>474_bases
TTGATTAACTTGATTAAAAAAGGTGACTATGTCAAAGTAGATTATATATTAGAAGTAGATGGAAAAGTTATTGACACATC
AATTGAAGAAGTAGCTAAAGAAAATAAAATATACTATCCTGAAAGAGAATATGAGCCAATTGGATTTATTGTAGGTAATG
GAGAATTAATCGAAGGTTTTGAAGAGGCTGTTATAGGCATGGAAGTTGGAGAAGAAAAAACTGTAACAATTCCTCCTGAA
AAAGGTTATGGACTTAGAGATGAGAGATTAATCCAAGAAATACCTAAGGAAATGTTTGCTGATGCTGACTTTGAACCACA
GGAGGGAATGTTAATCTTAGCCAGTGGAATTCCTGCAAAGATAATAAAAGTTACTGATGATACTGTAACTTTAGACTTTA
ACCACGAGCTTGCTGGAAAAGAATTAAAATTCACAATAAAAGTAAGAGATGTCCAGCCAGCTGAGTCAGAATAA

Upstream 100 bases:

>100_bases
CTCCATAAAAACCCCCAAATATGACGCTTTTGTCCATAAAAAATAATAACAAAAAACTATTTATATACCCTTCACAAAAA
GTATTTGGAAAGGTTAGGAG

Downstream 100 bases:

>100_bases
TTTCTTTCTTTAATTCTATTTTTTATTTTTAGTCTTTAAGATTAGTAATTAAATATTAAATACCAACACTTTTTTATATC
AAACTTTTTAAAGTTCTTCA

Product: peptidyl-prolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Rotamase

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MINLIKKGDYVKVDYILEVDGKVIDTSIEEVAKENKIYYPEREYEPIGFIVGNGELIEGFEEAVIGMEVGEEKTVTIPPE
KGYGLRDERLIQEIPKEMFADADFEPQEGMLILASGIPAKIIKVTDDTVTLDFNHELAGKELKFTIKVRDVQPAESE

Sequences:

>Translated_157_residues
MINLIKKGDYVKVDYILEVDGKVIDTSIEEVAKENKIYYPEREYEPIGFIVGNGELIEGFEEAVIGMEVGEEKTVTIPPE
KGYGLRDERLIQEIPKEMFADADFEPQEGMLILASGIPAKIIKVTDDTVTLDFNHELAGKELKFTIKVRDVQPAESE
>Mature_157_residues
MINLIKKGDYVKVDYILEVDGKVIDTSIEEVAKENKIYYPEREYEPIGFIVGNGELIEGFEEAVIGMEVGEEKTVTIPPE
KGYGLRDERLIQEIPKEMFADADFEPQEGMLILASGIPAKIIKVTDDTVTLDFNHELAGKELKFTIKVRDVQPAESE

Specific function: PPIases accelerate the folding of proteins

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1789748, Length=116, Percent_Identity=40.5172413793103, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786211, Length=159, Percent_Identity=30.188679245283, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FKBP1_METJA (Q57726)

Other databases:

- EMBL:   L77117
- PIR:   G64334
- RefSeq:   NP_247251.1
- ProteinModelPortal:   Q57726
- SMR:   Q57726
- GeneID:   1451133
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0278
- NMPDR:   fig|243232.1.peg.288
- TIGR:   MJ0278
- HOGENOM:   HBG731200
- OMA:   NHELAGE
- ProtClustDB:   CLSK2749865
- BioCyc:   MJAN243232:MJ_0278-MONOMER
- BRENDA:   5.2.1.8
- InterPro:   IPR001179
- PANTHER:   PTHR10516

Pfam domain/function: PF00254 FKBP_C

EC number: =5.2.1.8

Molecular weight: Translated: 17680; Mature: 17680

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLIKKGDYVKVDYILEVDGKVIDTSIEEVAKENKIYYPEREYEPIGFIVGNGELIEGF
CCCCCCCCCEEEEEEEEEECCEEECHHHHHHHHCCCEECCCCCCCCEEEEEECCHHHHHH
EEAVIGMEVGEEKTVTIPPEKGYGLRDERLIQEIPKEMFADADFEPQEGMLILASGIPAK
HHHEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEE
IIKVTDDTVTLDFNHELAGKELKFTIKVRDVQPAESE
EEEEECCEEEEEECCCCCCCEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MINLIKKGDYVKVDYILEVDGKVIDTSIEEVAKENKIYYPEREYEPIGFIVGNGELIEGF
CCCCCCCCCEEEEEEEEEECCEEECHHHHHHHHCCCEECCCCCCCCEEEEEECCHHHHHH
EEAVIGMEVGEEKTVTIPPEKGYGLRDERLIQEIPKEMFADADFEPQEGMLILASGIPAK
HHHEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEE
IIKVTDDTVTLDFNHELAGKELKFTIKVRDVQPAESE
EEEEECCEEEEEECCCCCCCEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087